KEGG   Phocoena sinus (vaquita): 116760381
Entry
116760381         CDS       T07759                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu01522  Endocrine resistance
psiu04110  Cell cycle
psiu04115  p53 signaling pathway
psiu04151  PI3K-Akt signaling pathway
psiu04218  Cellular senescence
psiu04530  Tight junction
psiu04660  T cell receptor signaling pathway
psiu04933  AGE-RAGE signaling pathway in diabetic complications
psiu04934  Cushing syndrome
psiu05160  Hepatitis C
psiu05162  Measles
psiu05163  Human cytomegalovirus infection
psiu05164  Influenza A
psiu05165  Human papillomavirus infection
psiu05166  Human T-cell leukemia virus 1 infection
psiu05167  Kaposi sarcoma-associated herpesvirus infection
psiu05169  Epstein-Barr virus infection
psiu05200  Pathways in cancer
psiu05203  Viral carcinogenesis
psiu05212  Pancreatic cancer
psiu05214  Glioma
psiu05218  Melanoma
psiu05219  Bladder cancer
psiu05220  Chronic myeloid leukemia
psiu05222  Small cell lung cancer
psiu05223  Non-small cell lung cancer
psiu05224  Breast cancer
psiu05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    116760381 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    116760381 (CDK4)
   04115 p53 signaling pathway
    116760381 (CDK4)
   04218 Cellular senescence
    116760381 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    116760381 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    116760381 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116760381 (CDK4)
   05203 Viral carcinogenesis
    116760381 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    116760381 (CDK4)
   05225 Hepatocellular carcinoma
    116760381 (CDK4)
   05214 Glioma
    116760381 (CDK4)
   05220 Chronic myeloid leukemia
    116760381 (CDK4)
   05218 Melanoma
    116760381 (CDK4)
   05219 Bladder cancer
    116760381 (CDK4)
   05224 Breast cancer
    116760381 (CDK4)
   05222 Small cell lung cancer
    116760381 (CDK4)
   05223 Non-small cell lung cancer
    116760381 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116760381 (CDK4)
   05160 Hepatitis C
    116760381 (CDK4)
   05164 Influenza A
    116760381 (CDK4)
   05162 Measles
    116760381 (CDK4)
   05163 Human cytomegalovirus infection
    116760381 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116760381 (CDK4)
   05169 Epstein-Barr virus infection
    116760381 (CDK4)
   05165 Human papillomavirus infection
    116760381 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    116760381 (CDK4)
   04934 Cushing syndrome
    116760381 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    116760381 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:psiu01001]
    116760381 (CDK4)
Enzymes [BR:psiu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     116760381 (CDK4)
Protein kinases [BR:psiu01001]
 Serine/threonine kinases: CMGC group
  CDK family
   116760381 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 116760381
NCBI-ProteinID: XP_032501097
Ensembl: ENSPSNG00000007800
UniProt: A0A8C9BL24
LinkDB
Position
10:58183765..58186785
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacccctcgatatgagccagtggctgagattggtgttggtgcctatgggacggtg
tataaggcccgtgatccccacagtggccactttgtggccctcaagagcgtaagagtcccc
aatggaggaggtgctggagggggcctgcccatcagcacagtccgtgaggtggctttactg
cggcggctggaggcttttgagcatcccaatgttgtgcggctgatggacgtctgtgccaca
gcccgaactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagaccta
aggacatatctggacaaggcacccccgccaggcctgccagtggagaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaactgcatcgttcatcgagac
ttgaagccagagaacattctggtgacaagtggtgggacagttaagctggccgactttggc
ctggccagaatctacagctaccagatggcacttacccctgtggttgttacactctggtac
cgtgctccagaagttcttttgcagtctacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgatcggactgcccccagaggatgactggccccga
gatgtgtctctaccccgaggagccttttcccccagagggccccgccccgtgcagtcggtg
gtacctgagatggaagagtctggggcacagctgctgctggagatgctgacttttaaccca
cacaagcggatctctgccttccgagccctgcagcactcctatctacataaggcagaaggt
aacccagagtga

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