Polyodon spathula (Mississippi paddlefish): 121320746
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Entry
121320746 CDS
T07273
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pspa
Polyodon spathula (Mississippi paddlefish)
Pathway
pspa00140
Steroid hormone biosynthesis
pspa01100
Metabolic pathways
Module
pspa_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pspa_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pspa_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pspa00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121320746 (hsd3b1)
Enzymes [BR:
pspa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
121320746 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
121320746 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
KR
RmlD_sub_bind
NmrA
Sacchrp_dh_NADP
adh_short
Motif
Other DBs
NCBI-GeneID:
121320746
NCBI-ProteinID:
XP_041115270
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Position
9:36192774..36195986
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AA seq
377 aa
AA seq
DB search
MSLAGEVCLITGAFGFLGQRIIQLLLQEDELAEIRLLDRHVRPDKLESLEEFRGQTKLTV
FEGDIRDAELLKKACQHVSLVIHTASLIDVIGVIDERELEEVNVKGTKFLLEACVQENVK
SFIYTSSIEVAGPNTRGDPMINGNEDTVYSCSLKFPYSKTKFQAEQLVLQFNGEGLRSQD
KIVTCALRPMYIYGEGCNFLLGHMDAGIRNGDILLRSSKKESVVNPVYVGNVAWAHILAA
KAMRDPKKATLIGGKFYYISDDTPHVSYSDFNHVVLKPLGFGIQERLALPLPLLLFLTLL
LEMVQVFLKPFVKYTPKMNRQLLIMLNTQFSFTYEKAQRAFGYTPKYSWEDARTFTTTWL
ESVLPQHRALLKTHSQH
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtctcttgctggtgaagtttgtctcattactggagcatttggattcctgggacaaaga
attatccagcttctgctgcaggaggatgagcttgcagagatcaggcttcttgacaggcat
gtcaggcctgataaacttgaatctttggaagagtttcggggccaaaccaagctgactgtg
tttgagggggacatcagagatgcagagctcctcaagaaagcttgccagcacgtcagcctt
gtgatccacacagcttccctcattgatgtcattggagttatagatgaaagggaactagaa
gaagtgaatgttaaaggtaccaagttcttgctggaagcttgtgttcaagagaacgtgaag
tccttcatctacaccagtagcattgaggtggcaggtccaaacacccggggagaccctatg
atcaatgggaatgaagatacagtttattcatgctccttgaaatttccctacagcaagacc
aagttccaagctgaacagttggttctacagttcaatggggagggtcttagaagtcaagac
aaaatagtgacatgtgccttgcggcccatgtatatctatggggaaggttgtaacttcctt
ttaggccacatggatgccggaatcagaaatggggacatattgttacgtagctccaaaaag
gagtctgttgtgaacccagtgtatgtaggcaacgtagcctgggcacatattttagcagcc
aaagctatgagggatcccaagaaagccaccttgataggtggtaaattctactacatctca
gatgacactccacatgtaagctactcagatttcaaccacgtggtgttaaagcccttggga
ttcggtattcaggagaggctcgctctccctctgccactgctgctgttcctcacactcctt
ctggagatggtgcaggtctttctgaaaccttttgtgaagtacactcccaaaatgaaccgc
cagcttctcatcatgctcaacacgcagtttagcttcacctatgaaaaggcccaaagggct
tttggttacactccaaagtacagctgggaggatgctaggacctttactaccacctggctt
gaatctgttttgccacagcaccgtgcacttctgaaaacacattctcagcattag
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