KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111520328
Entry
111520328         CDS       T07491                                 
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh04010  MAPK signaling pathway
pteh04020  Calcium signaling pathway
pteh04022  cGMP-PKG signaling pathway
pteh04024  cAMP signaling pathway
pteh04260  Cardiac muscle contraction
pteh04261  Adrenergic signaling in cardiomyocytes
pteh04270  Vascular smooth muscle contraction
pteh04713  Circadian entrainment
pteh04720  Long-term potentiation
pteh04723  Retrograde endocannabinoid signaling
pteh04724  Glutamatergic synapse
pteh04725  Cholinergic synapse
pteh04726  Serotonergic synapse
pteh04727  GABAergic synapse
pteh04728  Dopaminergic synapse
pteh04742  Taste transduction
pteh04911  Insulin secretion
pteh04912  GnRH signaling pathway
pteh04921  Oxytocin signaling pathway
pteh04924  Renin secretion
pteh04925  Aldosterone synthesis and secretion
pteh04927  Cortisol synthesis and secretion
pteh04929  GnRH secretion
pteh04930  Type II diabetes mellitus
pteh04934  Cushing syndrome
pteh04935  Growth hormone synthesis, secretion and action
pteh05010  Alzheimer disease
pteh05020  Prion disease
pteh05022  Pathways of neurodegeneration - multiple diseases
pteh05031  Amphetamine addiction
pteh05207  Chemical carcinogenesis - receptor activation
pteh05410  Hypertrophic cardiomyopathy
pteh05412  Arrhythmogenic right ventricular cardiomyopathy
pteh05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111520328 (CACNA1C)
   04020 Calcium signaling pathway
    111520328 (CACNA1C)
   04024 cAMP signaling pathway
    111520328 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    111520328 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    111520328 (CACNA1C)
   04929 GnRH secretion
    111520328 (CACNA1C)
   04912 GnRH signaling pathway
    111520328 (CACNA1C)
   04921 Oxytocin signaling pathway
    111520328 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    111520328 (CACNA1C)
   04924 Renin secretion
    111520328 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    111520328 (CACNA1C)
   04927 Cortisol synthesis and secretion
    111520328 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    111520328 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    111520328 (CACNA1C)
   04270 Vascular smooth muscle contraction
    111520328 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    111520328 (CACNA1C)
   04727 GABAergic synapse
    111520328 (CACNA1C)
   04725 Cholinergic synapse
    111520328 (CACNA1C)
   04728 Dopaminergic synapse
    111520328 (CACNA1C)
   04726 Serotonergic synapse
    111520328 (CACNA1C)
   04720 Long-term potentiation
    111520328 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    111520328 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    111520328 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    111520328 (CACNA1C)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    111520328 (CACNA1C)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111520328 (CACNA1C)
   05020 Prion disease
    111520328 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    111520328 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    111520328 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    111520328 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    111520328 (CACNA1C)
   05414 Dilated cardiomyopathy
    111520328 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    111520328 (CACNA1C)
   04934 Cushing syndrome
    111520328 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pteh04040]
    111520328 (CACNA1C)
Ion channels [BR:pteh04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   111520328 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans GPHH CAC1F_C Ca_chan_IQ PKD_channel
Other DBs
NCBI-GeneID: 111520328
NCBI-ProteinID: XP_026303583
Ensembl: ENSPTEG00000038165
LinkDB
Position
10:2406764..3046880
AA seq 2323 aa
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKYPLPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK
VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT
CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF
QCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKA
RGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTE
NVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLN
TLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVC
GGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLL
LFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM
AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKK
LARTASPEKKQEMVEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPY
PNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIV
NDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNAD
YVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKIL
RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYT
CSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGW
PELLYRSIDSHTEDRGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEY
KNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLA
MQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIID
VILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFR
LFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALND
TTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGS
SFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAK
GRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTA
LRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGEGTFQRTPDLSKDGCEKGAM
CPSPPATHRLPSMPSSLLDGQVDSSMRGQPSPQFTHRQTFRRVNWLGGGCQGPGGTGLGP
RLWLAGWRMPGPWRDRPWPEAVAGWVEDARALEGQALARGYDWLASLEKREHDPHHPPLG
FQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYY
QSDSRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNA
NNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHALVWEGLELRRD
SGSAGTQAHCPLLRRANSSRCHSGESQPAMAGPEETCQDETCEVKMNHDTEACSEPSLLS
TEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDIS
QKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPIPTLRLE
GAESSEKLNSSFPSIHCGSWAETTPGGGDSSATRRARPVSLMVPGQAGAPGRQFHGSASS
LVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALL
PFVNCRDAGQDRAGGEEDGGCARARGRLSEEELQDSRVYVSSL
NT seq 6972 nt   +upstreamnt  +downstreamnt
atggtcaatgagaatacgaggatgtacattccagaggaaaaccaccaaggttccaactat
gggagcccacgccccgcccatgccaacatgaatgccaatgcggccgcgggactggcccct
gagcacatccccaccccgggggccgccctgtcctggcaggcggccatcgatgcagcccgg
caggctaagctgatgggcagcgctggcaacgcgaccatctccacagtcagctccacgcag
cggaagcggcagcaatacgggaagcccaagaagcagggcagcaccacggccacacgcccg
ccccgagccctgctctgcctgaccctgaagaaccccatccggagggcctgcatcagcatt
gtcgaatggaaatatcctttaccatttgaaataattattttactgactatttttgccaat
tgtgtggccttagcgatctatattccctttccagaagatgattccaacgccactaattcc
aacctggaacgagtggaatatctctttctcataatttttacggtggaagcatttttaaaa
gtcatcgcctatggactcctgtttcaccccaatgcctacctccgcaacggctggaatctg
ctcgattttatcattgtggttgtggggctttttagtgcaattttagaacaagcaaccaaa
gcagacggggcaaatgctctcggagggaaaggggccggatttgatgtgaaagcgctgagg
gccttccgcgtgctgcgacccctgcggctggtgtccggagtcccaagtctccaggtggtc
ctgaattccatcatcaaggccatggtccccctgctgcacatcgccctgctcgtgctgttt
gtcatcatcatctacgccatcatcggcctggagctcttcatggggaagatgcacaagacc
tgctacaaccaggagggcatagcagatgttccagcagaagatgacccttccccttgtgcg
ctggaaacaggccatgggcggcagtgccagaacggcacggtgtgcaagcccggctgggat
ggtcccaagcacggcatcaccaactttgacaactttgccttcgccatgctcacggtgttc
cagtgcatcaccatggagggctggacggacgtgctgtactgggtcaatgatgccgtagga
agggactggccctggatctattttgttacactaatcatcatagggtcattttttgtactt
aacttggttctcggtgtgcttagcggagagttttccaaagagagggagaaggccaaggcc
cggggagatttccagaagctgcgggagaagcagcagctagaagaggatctcaaaggctac
ctggactggatcactcaggccgaagacatcgatcccgagaacgaggacgaaggcatggat
gaggagaagccccgaaacatgagcatgcccaccagtgagaccgagtccgtcaacaccgaa
aacgtggctggaggtgacatcgagggagaaaactgcggggccaggctggcccaccggatc
tccaagtcaaagttcagccgctactggcgccggtggaaccggttctgcagaagaaagtgc
cgtgccgcagtcaagtctaatgtcttctactggctggtgattttcctggtgttcctcaac
actctcaccattgcctctgagcactacaaccagccccactggctcacagaagtccaagac
acggcgaacaaggccctgctggccctgttcacggcagagatgctcctgaagatgtacagc
ctgggcctgcaggcctacttcgtgtccctcttcaaccgctttgactgcttcgtcgtgtgt
ggcggcatcctggagaccatcctggtggagaccaagatcatgtcccccctgggcatctcc
gtgctcagatgtgtccggttgctgaggatattcaagatcacgaggtactggaactccttg
agcaacctggtggcatccttgctgaactctgtgcgctccatcgcctccctgctccttctc
ctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggaggaaagttc
aactttgatgagatgcagacccggaggagcacatttgataacttcccccagtccctcctc
actgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatg
gcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttc
atctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaacctggct
gacgccgagagcctcacatctgcccaaaaggaggaggaagaggagaaggagagaaagaag
ctggccaggactgccagcccagagaagaaacaagagatggtagagaagccggcagtggag
gaatccaaggaggagaagattgagctgaaatccatcacggctgacggagagtctccaccc
accaccaagatcaacatggatgacctccagcctaatgaaaatgaggataagagcccctac
cccaacccagaaactacaggagaagaggatgaggaggagccagagatgcctgtcggccct
cgcccacgaccactctctgagcttcaccttaaggaaaaggcagtgcccatgccagaagcc
agcgcgtttttcatcttcagctctaacaacaggtttcgcctccagtgccaccgcattgtc
aacgacacgatcttcaccaacctgatcctcttcttcattctgctcagcagcatttccctg
gctgctgaggacccggtccagcacacctccttcaggaaccatattctgttttattttgat
attgtttttaccaccattttcaccattgaaattgctctgaagatcctaggcaatgcagac
tatgtcttcactagtatctttacattagaaattatccttaagatgacggcttatggggca
tttctgcacaagggctctttctgccggaactacttcaacatcctggacctgctggtggtc
agcgtgtccctcatctccttcggcatccagtccagtgcaatcaatgtcgtgaagatcttg
cgagtcctgcgagtactccggcccctgagggctatcaacagggccaaggggctaaagcat
gtggttcagtgtgtgtttgtcgctatccggaccatcgggaacatcgtgattgtcaccacc
ctgctgcagttcatgttcgcctgcatcggggtccagctcttcaagggaaagctgtacacc
tgttcagacagttccaagcagacagaggcggaatgcaagggcaactacatcacgtacaaa
gacggggaggttgaccaccccatcatccaaccccgcagctgggagaacagcaagtttgac
tttgacaatgttctggcagccatgatggccctcttcaccgtctccaccttcgaagggtgg
ccagagctgctgtaccgctccatcgactcccacaccgaagacaggggtcccatctacaac
taccgcgtggagatctccatcttcttcatcatctacatcatcatcatcgccttcttcatg
atgaacatctttgtgggcttcgtcattgtcaccttccaggagcagggggagcaggagtac
aagaactgtgagctggacaagaaccagcgacagtgtgtggaatacgccctcaaggcccgg
cccctgcggaggtatatccccaagaaccagcaccagtacaaagtgtggtacgtggtcaac
tccacctacttcgagtacctgatgttcgtcctcatcctgctcaacaccatctgcctggcc
atgcagcactacggccagagctgcctgttcaaaatcgccatgaacatcctcaacatgctc
ttcaccggtctcttcaccgtggagatgatcctgaagctcattgccttcaaacccaagggt
tactttagtgatccctggaatgtttttgacttcctcatcgtaattggcagcataattgac
gtcattctcagtgagactaatcactatttctgtgatgcatggaatacatttgacgccttg
attgttgtgggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacc
caatgctctccctctatgaacgcagaggaaaactcgcgcatctccatcaccttcttccgc
ctattccgggtcatgcgcctggtgaagctgctgagccgcggggagggcatccggacgctg
ctgtggaccttcatcaagtccttccaggccctgccctatgtggctctcctgatcgtgatg
ctgttcttcatctatgcggtgatcgggatgcaggtgtttgggaaaattgccctgaatgat
accacagagatcaaccggaacaacaactttcagaccttcccccaggccgtgctgctcctc
ttcaggtgtgccaccggggaggcctggcaggacatcatgctggcctgcatgccaggcaag
aagtgtgccccggagtccgagcccagcaacagcacggagggtgaaacaccctgtggcagc
agctttgccgtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaac
ctctttgtagctgtcatcatggacaactttgactacctgacaagagactggtccatcctc
ggtccccaccacctggatgagtttaaaagaatctgggccgagtatgaccctgaagccaag
ggtcgtatcaaacacctggatgtggtgaccctcctccggcggattcagcccccactgggt
tttgggaagttgtgccctcaccgcgtggcttgcaaacgcctggtctccatgaacatgcct
ctgaacagcgacgggacagtcatgttcaatgccaccctgtttgccctggtcaggacagcc
ctgaggatcaaaacagaagggaacctcgaacaggccaatgaggagctgcgggccatcatc
aagaagatctggaagcggaccagcatgaagctgctggaccaggtggtgccccctgcgggc
gagggaacctttcagagaactccagacctttccaaagatggctgtgagaagggggcgatg
tgcccttccccacctgccacccaccgactgccctccatgccttcatccctcctggatggg
caagtggattcttccatgagagggcagcccagcccccagttcacacacagacaaaccttc
cggagggtcaactggctgggtggaggatgccagggccctggagggacaggccttggcccg
aggctgtggctggctgggtggaggatgccagggccctggagggacaggccttggcccgag
gctgtggctggctgggtggaggatgccagggccctggagggacaggccttggcccgaggc
tatgactggctggcgagcttggagaaaagggagcacgatcctcaccatcctccgcttggg
ttccaggctggcttgcgcacactgcatgacatcgggcctgagatccgacgggccatctct
ggagatctcaccgctgaggaggagctggacaaggccatgaaggaggctgtgtccgctgct
tctgaagatgacatcttcaggagggccggtggcctgttcggcaaccacgtcagctactac
caaagtgacagccggagcgccttcccccagaccttcaccactcagcgcccgctgcacatc
aacaaggcgggcagcagccagggcgacactgagtcgccgtcccacgagaagctggtggac
tccaccttcacccccagcagctactcgtccaccggctccaacgccaacatcaacaacgcc
aacaacaccgccctgggtcgcctccctcgccccgctggctaccccagcacggtcagcact
gtggagggccatgggccgcctttgtcccctgccatccgggtgcaggaggtggcgtggaag
ctcagctccaacagggaaaggcacgccctggtgtgggagggtctggagctcaggagggat
tcaggctcagcagggactcaggctcactgccctctgctcaggagagcaaactcctctagg
tgccactccggggagagccagccagccatggcgggtccggaggagacgtgtcaggatgag
acctgtgaagtgaagatgaaccacgacacggaggcctgcagtgagcccagcctgctctcc
acagagatgctgtcctaccaggatgacgaaaatcggcaactgacgctcccagaggaggac
aagagggacatccggcaatccccaaagaggggtttcctccgctccgcctcactaggtcga
agggcctccttccacctggaatgtctgaagcgacagaaggaccgagggggagacatctct
cagaagacagtcctgcccttgcatctggtccatcatcaggcattggcagtggcaggcctg
agccccctcctccagagaagccattcccctgcctcattccccaggccttttgccaccccg
ccggccacacctggcagccgaggctggccgccacagcccatccccaccctgcggctggag
ggcgccgagtccagtgagaaactcaacagcagcttcccgtccatccactgcggctcctgg
gctgagaccacccccgggggcggggacagcagcgccacccggagagcccggcccgtctcc
ctcatggtgcccggccaggctggggccccggggaggcagttccacggcagtgccagcagc
ctggtggaagcggtcttgatttctgaaggactggggcagttcgctcaagatcccaagttc
atcgaggtcaccacccaggagctggcggacgcctgcgacatgaccatagaggagatggag
agcgcggccgacaacatcctcagcgggggcgccccacagagccccaatggcgccctctta
ccctttgtgaactgcagggacgcggggcaggaccgagccgggggcgaagaggacgggggc
tgtgcgcgcgcgcgggggcgcctgagcgaggaggagctccaggacagcagggtctacgtc
agcagcctgtag

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