KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111541790
Entry
111541790         CDS       T07491                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh01522  Endocrine resistance
pteh04110  Cell cycle
pteh04115  p53 signaling pathway
pteh04151  PI3K-Akt signaling pathway
pteh04218  Cellular senescence
pteh04530  Tight junction
pteh04660  T cell receptor signaling pathway
pteh04933  AGE-RAGE signaling pathway in diabetic complications
pteh04934  Cushing syndrome
pteh05160  Hepatitis C
pteh05162  Measles
pteh05163  Human cytomegalovirus infection
pteh05164  Influenza A
pteh05165  Human papillomavirus infection
pteh05166  Human T-cell leukemia virus 1 infection
pteh05167  Kaposi sarcoma-associated herpesvirus infection
pteh05169  Epstein-Barr virus infection
pteh05200  Pathways in cancer
pteh05203  Viral carcinogenesis
pteh05212  Pancreatic cancer
pteh05214  Glioma
pteh05218  Melanoma
pteh05219  Bladder cancer
pteh05220  Chronic myeloid leukemia
pteh05222  Small cell lung cancer
pteh05223  Non-small cell lung cancer
pteh05224  Breast cancer
pteh05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    111541790 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    111541790 (CDK4)
   04115 p53 signaling pathway
    111541790 (CDK4)
   04218 Cellular senescence
    111541790 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    111541790 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    111541790 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111541790 (CDK4)
   05203 Viral carcinogenesis
    111541790 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    111541790 (CDK4)
   05225 Hepatocellular carcinoma
    111541790 (CDK4)
   05214 Glioma
    111541790 (CDK4)
   05220 Chronic myeloid leukemia
    111541790 (CDK4)
   05218 Melanoma
    111541790 (CDK4)
   05219 Bladder cancer
    111541790 (CDK4)
   05224 Breast cancer
    111541790 (CDK4)
   05222 Small cell lung cancer
    111541790 (CDK4)
   05223 Non-small cell lung cancer
    111541790 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111541790 (CDK4)
   05160 Hepatitis C
    111541790 (CDK4)
   05164 Influenza A
    111541790 (CDK4)
   05162 Measles
    111541790 (CDK4)
   05163 Human cytomegalovirus infection
    111541790 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111541790 (CDK4)
   05169 Epstein-Barr virus infection
    111541790 (CDK4)
   05165 Human papillomavirus infection
    111541790 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    111541790 (CDK4)
   04934 Cushing syndrome
    111541790 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    111541790 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pteh01001]
    111541790 (CDK4)
Enzymes [BR:pteh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     111541790 (CDK4)
Protein kinases [BR:pteh01001]
 Serine/threonine kinases: CMGC group
  CDK family
   111541790 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 111541790
NCBI-ProteinID: XP_023066417
Ensembl: ENSPTEG00000027518
UniProt: A0A8C9I1L8
LinkDB
Position
10:complement(54866273..54870569)
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgggaggtggccttactg
aggcgactggaggcttttgaacatcccaatgttgtccggctgatggatgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaagaccta
aggacgtatctggacaaggcacccccaccaggcttgccagctgagaccatcaaggatttg
atgcgccagtttctaagaggcctagatttccttcatgcaaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctggccagaatctacagctaccagatggcacttacacccgtggttgttacgctgtggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagtcgggagcacagctgctgctggaaatgctgacttttaaccca
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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