KEGG T07491: 111542428

Piliocolobus tephrosceles (Ugandan red Colobus): 111542428

Entry

111542428         CDS       T07491

Symbol

GRB2

Name

(RefSeq) growth factor receptor-bound protein 2

K04364

growth factor receptor-bound protein 2

Organism

pteh Piliocolobus tephrosceles (Ugandan red Colobus)

Pathway

pteh01521

EGFR tyrosine kinase inhibitor resistance

pteh01522

Endocrine resistance

pteh04010

MAPK signaling pathway

pteh04012

ErbB signaling pathway

pteh04014

Ras signaling pathway

pteh04062

Chemokine signaling pathway

pteh04068

FoxO signaling pathway

pteh04072

Phospholipase D signaling pathway

pteh04150

mTOR signaling pathway

pteh04151

PI3K-Akt signaling pathway

pteh04380

Osteoclast differentiation

pteh04510

Focal adhesion

pteh04540

Gap junction

pteh04550

Signaling pathways regulating pluripotency of stem cells

pteh04630

JAK-STAT signaling pathway

pteh04650

Natural killer cell mediated cytotoxicity

pteh04660

T cell receptor signaling pathway

pteh04662

B cell receptor signaling pathway

pteh04664

Fc epsilon RI signaling pathway

pteh04714

Thermogenesis

pteh04722

Neurotrophin signaling pathway

pteh04910

Insulin signaling pathway

pteh04912

GnRH signaling pathway

pteh04915

Estrogen signaling pathway

pteh04917

Prolactin signaling pathway

pteh04926

Relaxin signaling pathway

pteh04935

Growth hormone synthesis, secretion and action

pteh05034

Alcoholism

pteh05160

Hepatitis C

pteh05161

Hepatitis B

pteh05163

Human cytomegalovirus infection

pteh05165

Human papillomavirus infection

pteh05200

Pathways in cancer

pteh05203

Viral carcinogenesis

pteh05205

Proteoglycans in cancer

pteh05206

MicroRNAs in cancer

pteh05207

Chemical carcinogenesis - receptor activation

pteh05208

Chemical carcinogenesis - reactive oxygen species

pteh05210

Colorectal cancer

pteh05211

Renal cell carcinoma

pteh05213

Endometrial cancer

pteh05214

Glioma

pteh05215

Prostate cancer

pteh05220

Chronic myeloid leukemia

pteh05221

Acute myeloid leukemia

pteh05223

Non-small cell lung cancer

pteh05224

Breast cancer

pteh05225

Hepatocellular carcinoma

pteh05226

Gastric cancer

pteh05231

Choline metabolism in cancer

Brite

KEGG Orthology (KO) [BR:pteh00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111542428 (GRB2)
   04012 ErbB signaling pathway
    111542428 (GRB2)
   04014 Ras signaling pathway
    111542428 (GRB2)
   04630 JAK-STAT signaling pathway
    111542428 (GRB2)
   04068 FoxO signaling pathway
    111542428 (GRB2)
   04072 Phospholipase D signaling pathway
    111542428 (GRB2)
   04151 PI3K-Akt signaling pathway
    111542428 (GRB2)
   04150 mTOR signaling pathway
    111542428 (GRB2)
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    111542428 (GRB2)
   04540 Gap junction
    111542428 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    111542428 (GRB2)
09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    111542428 (GRB2)
   04660 T cell receptor signaling pathway
    111542428 (GRB2)
   04662 B cell receptor signaling pathway
    111542428 (GRB2)
   04664 Fc epsilon RI signaling pathway
    111542428 (GRB2)
   04062 Chemokine signaling pathway
    111542428 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    111542428 (GRB2)
   04912 GnRH signaling pathway
    111542428 (GRB2)
   04915 Estrogen signaling pathway
    111542428 (GRB2)
   04917 Prolactin signaling pathway
    111542428 (GRB2)
   04926 Relaxin signaling pathway
    111542428 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    111542428 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    111542428 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111542428 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    111542428 (GRB2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111542428 (GRB2)
   05206 MicroRNAs in cancer
    111542428 (GRB2)
   05205 Proteoglycans in cancer
    111542428 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    111542428 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    111542428 (GRB2)
   05203 Viral carcinogenesis
    111542428 (GRB2)
   05231 Choline metabolism in cancer
    111542428 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    111542428 (GRB2)
   05225 Hepatocellular carcinoma
    111542428 (GRB2)
   05226 Gastric cancer
    111542428 (GRB2)
   05214 Glioma
    111542428 (GRB2)
   05221 Acute myeloid leukemia
    111542428 (GRB2)
   05220 Chronic myeloid leukemia
    111542428 (GRB2)
   05211 Renal cell carcinoma
    111542428 (GRB2)
   05215 Prostate cancer
    111542428 (GRB2)
   05213 Endometrial cancer
    111542428 (GRB2)
   05224 Breast cancer
    111542428 (GRB2)
   05223 Non-small cell lung cancer
    111542428 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    111542428 (GRB2)
   05160 Hepatitis C
    111542428 (GRB2)
   05163 Human cytomegalovirus infection
    111542428 (GRB2)
   05165 Human papillomavirus infection
    111542428 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    111542428 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    111542428 (GRB2)
   01522 Endocrine resistance
    111542428 (GRB2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pteh04131]
    111542428 (GRB2)
Membrane trafficking [BR:pteh04131]
Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    111542428 (GRB2)

SSDB

Motif

Pfam:

SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

16:complement(68959585..69046379)

AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV

NT seq 654 nt +upstreamnt +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgatgagctgagcttcaaa
aggggggacatcctcaaggttttgaacgaagaatgtgatcagaactggtacaaggcagag
ctcaatggaaaagacggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagtgagagcgctcctggggacttctccctctctgtcaag
tttggaaacgatgtgcagcacttcaaggtgctccgagacggagccggcaagtacttcctc
tgggtggtgaagttcaattctttgaatgagctggtggattatcacagatctacatctgtc
tccagaaaccagcagatattcctgcgggacatagaacaggtgccacagcagccgacatac
gtccaggccctctttgactttgatccccaggaggatggagagctgggcttccgccgggga
gattttatccatgtcatggataactcagaccccaactggtggaaaggagcttgccacggg
cagaccggcatgtttccccgcaattacgtcacccctgtgaaccggaacgtctaa

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