KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111547169
Entry
111547169         CDS       T07491                                 
Symbol
CASP8
Name
(RefSeq) caspase-8 isoform X1
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh01524  Platinum drug resistance
pteh04115  p53 signaling pathway
pteh04210  Apoptosis
pteh04215  Apoptosis - multiple species
pteh04217  Necroptosis
pteh04620  Toll-like receptor signaling pathway
pteh04621  NOD-like receptor signaling pathway
pteh04622  RIG-I-like receptor signaling pathway
pteh04623  Cytosolic DNA-sensing pathway
pteh04625  C-type lectin receptor signaling pathway
pteh04657  IL-17 signaling pathway
pteh04668  TNF signaling pathway
pteh04932  Non-alcoholic fatty liver disease
pteh04936  Alcoholic liver disease
pteh05010  Alzheimer disease
pteh05016  Huntington disease
pteh05022  Pathways of neurodegeneration - multiple diseases
pteh05132  Salmonella infection
pteh05134  Legionellosis
pteh05142  Chagas disease
pteh05145  Toxoplasmosis
pteh05152  Tuberculosis
pteh05160  Hepatitis C
pteh05161  Hepatitis B
pteh05162  Measles
pteh05163  Human cytomegalovirus infection
pteh05164  Influenza A
pteh05165  Human papillomavirus infection
pteh05167  Kaposi sarcoma-associated herpesvirus infection
pteh05168  Herpes simplex virus 1 infection
pteh05169  Epstein-Barr virus infection
pteh05170  Human immunodeficiency virus 1 infection
pteh05200  Pathways in cancer
pteh05203  Viral carcinogenesis
pteh05416  Viral myocarditis
pteh05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    111547169 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    111547169 (CASP8)
   04215 Apoptosis - multiple species
    111547169 (CASP8)
   04217 Necroptosis
    111547169 (CASP8)
   04115 p53 signaling pathway
    111547169 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111547169 (CASP8)
   04621 NOD-like receptor signaling pathway
    111547169 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    111547169 (CASP8)
   04623 Cytosolic DNA-sensing pathway
    111547169 (CASP8)
   04625 C-type lectin receptor signaling pathway
    111547169 (CASP8)
   04657 IL-17 signaling pathway
    111547169 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111547169 (CASP8)
   05203 Viral carcinogenesis
    111547169 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111547169 (CASP8)
   05161 Hepatitis B
    111547169 (CASP8)
   05160 Hepatitis C
    111547169 (CASP8)
   05164 Influenza A
    111547169 (CASP8)
   05162 Measles
    111547169 (CASP8)
   05168 Herpes simplex virus 1 infection
    111547169 (CASP8)
   05163 Human cytomegalovirus infection
    111547169 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    111547169 (CASP8)
   05169 Epstein-Barr virus infection
    111547169 (CASP8)
   05165 Human papillomavirus infection
    111547169 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111547169 (CASP8)
   05134 Legionellosis
    111547169 (CASP8)
   05152 Tuberculosis
    111547169 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111547169 (CASP8)
   05142 Chagas disease
    111547169 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111547169 (CASP8)
   05016 Huntington disease
    111547169 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    111547169 (CASP8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111547169 (CASP8)
   05416 Viral myocarditis
    111547169 (CASP8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    111547169 (CASP8)
   04932 Non-alcoholic fatty liver disease
    111547169 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    111547169 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pteh01002]
    111547169 (CASP8)
Enzymes [BR:pteh01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     111547169 (CASP8)
Peptidases and inhibitors [BR:pteh01002]
 Cysteine peptidases
  Family C14: caspase family
   111547169 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED DUF8196 PYRIN
Other DBs
NCBI-GeneID: 111547169
NCBI-ProteinID: XP_023074580
Ensembl: ENSPTEG00000028833
LinkDB
Position
11:87536096..87595289
AA seq 496 aa
MVPGKGGADYILLPFEEMDFSRNLYDIGEQLDSEDLASLKFLSLDCIPQRKQEPIKDALM
LFQRLQEKRMLEENNLSFLKELLFRINRLDLLTTYLNTRKEEMERELRAPGRAQISAYRV
MLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRV
CAQVNKRLLKIINDYEEFSRERTRSLEGSPDEGSNGEELCGLMTISDSPREQDSESQTLD
KVYQMKSKPRGYCLIINNYDFTKAREKVPKLHSIRDRNGTQLDAEALTATFEELHFEIKH
HNDCTVEKIYKILKTYQLMDHSNKDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGL
KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQLYLEMDLSSPQTRYIPDEADFLLGM
ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQM
PQPTFTLRKKLVFPSD
NT seq 1491 nt   +upstreamnt  +downstreamnt
atggtgccaggaaagggtggagcggattatattctcctgccttttgaagagatggacttc
agcagaaatctttatgatattggggaacaactggacagtgaagatctggcctccctcaag
ttcctgagcctggactgcatcccacaaaggaagcaagaacccatcaaggatgccttgatg
ttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtccttcctcaag
gagctgctcttccgaattaatagactggatttgctcactacttacctaaacactagaaag
gaggagatggaaagggaacttcgggcaccaggcagggctcagatttctgcctacagggtc
atgctctatcagatttcagaagaggtgagcagatcagaattgaggtcttttaagtttctt
ttgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctggatattttc
atagagatggagaagagggtcatcctgggagaaggaaagttggacatcctgaaaagagtc
tgtgcccaagtcaacaagaggctgctgaagataatcaatgactatgaagaattcagcaga
gagagaacaaggagccttgaaggaagtcctgatgaaggttcaaatggggaggagttgtgt
gggctaatgacaatctcggactctccaagagaacaggatagtgaatcacagactttggac
aaagtttaccaaatgaaaagcaaacctcggggatactgtctgatcatcaacaactacgat
tttacaaaagcacgggagaaagtgcccaaacttcacagcattagggacaggaatggaaca
caattggacgcagaggctttgaccgcgacctttgaagagcttcattttgagatcaagcac
cacaatgactgcacagtagagaaaatctataagattttgaaaacctaccaactcatggac
cacagtaacaaggattgctttatctgctgtatcctctcccatggagacaagggcatcatc
tatggcactgatggacaggaggcccccatctatgagctgacatctcagttcactggtttg
aagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcagggggat
aactatcagaaaggtatacctgttgagactgattcagaggagcaactctatttggaaatg
gatttatcatcacctcaaacgagatatatcccggatgaagctgactttctgctggggatg
gccactgtgaataactgtgtgtcctaccgaaaccctgcagagggaacctggtacatccag
tcactttgccagagcctgagagaacgatgtcctcgaggcgatgatattctcaccatcctg
actgaagtgaactatgaagtaagcaacaaggatgacaaaaaaaacatggggaaacagatg
ccacagccaactttcacactaagaaaaaaacttgtcttcccttctgattga

DBGET integrated database retrieval system