KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111549589
Entry
111549589         CDS       T07491                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like isoform X1
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00140  Steroid hormone biosynthesis
pteh01100  Metabolic pathways
pteh04913  Ovarian steroidogenesis
pteh04925  Aldosterone synthesis and secretion
pteh04927  Cortisol synthesis and secretion
pteh04934  Cushing syndrome
Module
pteh_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pteh_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pteh_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pteh_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    111549589
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    111549589
   04925 Aldosterone synthesis and secretion
    111549589
   04927 Cortisol synthesis and secretion
    111549589
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    111549589
Enzymes [BR:pteh01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     111549589
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     111549589
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd Polysacc_synt_2 NAD_binding_10 RmlD_sub_bind NmrA Sacchrp_dh_NADP KR Ldh_1_N Semialdhyde_dh adh_short
Other DBs
NCBI-GeneID: 111549589
NCBI-ProteinID: XP_023078510
Ensembl: ENSPTEG00000033798
LinkDB
Position
1:complement(101750677..101759016)
AA seq 373 aa
MTGWSCLVTGAGGFVGQRIVRLLVEEKELKEIRVLDKAFRPELREEFSKLQNKTKLTVLE
GDILDEPFLKRACQDVSVVIHTACIIDVFGVTHTESIMDVNVKGTQLLLEACVQASVPIF
IYTSTLEVAGPNSYKEIIQNGHEEEPLENTWSAPYPYSKKLAEKAVLAANGWTLKNGDTL
YTCALRPMYIYGEGGPFLSATINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
RDPKKAPSVRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSLPLFLMYWIGFLLEI
VRLLLRPVCTYRPPFSRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTMEWVGSL
VDRHKETLKSKTQ
NT seq 1122 nt   +upstreamnt  +downstreamnt
atgacgggctggagctgccttgtgacaggagcaggagggtttgtgggtcagaggatcgtc
cgcctcttggtggaggagaaggagctgaaggagatcagggtcttggacaaggccttcaga
ccagagctgagggaggaattttccaagctccagaacaagaccaagctgacagtgctggaa
ggagacattctggatgagccattcctgaagagagcctgccaggacgtctcagtcgtcatc
cacaccgcctgtatcattgatgtctttggtgtcactcacacagagtccatcatggatgtc
aatgtgaaaggtacccagctcctgttggaggcctgtgtccaagctagtgtgccaatcttc
atctacaccagtaccctagaggtagccgggcccaactcctacaaggaaatcatccagaac
ggccacgaagaagagcctctggaaaacacatggtctgctccatacccatacagcaaaaag
cttgctgagaaggctgtgctggcagctaatgggtggactctgaaaaatggtgatactttg
tacacttgtgccttaagacccatgtatatctatggggaaggaggcccattcctttctgcc
actataaatgaggccctgaacaacaatgggatcctgtcaagtgttggcaagttctccact
gtcaacccagtctatgttggcaacgtggcctgggcccacattctggccttgagggccctg
cgggaccccaagaaggccccaagtgtccgaggacagttctactatatctcagatgacacg
cctcaccaaagctatgataaccttaattacaccctgagcaaagagttcggcctccgcctt
gattccagatggagccttcctttattcctgatgtactggattggcttcctgctggaaata
gtgaggctcctgctcaggccagtttgcacctatcgaccgcccttcagtcgtcacacagtg
acattgtcaaatagcgtgttcaccttctcttacaagaaggctcagagagatctggcatat
aagccgctctacagctgggaggaagccaagcagaaaaccatggagtgggttggttccctt
gtggaccggcacaaggagaccctgaagtccaagactcagtga

DBGET integrated database retrieval system