Panthera tigris altaica (Amur tiger): 102952189 Help Entry 102952189         CDS       T02988                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg04022   cGMP-PKG signaling pathway ptg04068   FoxO signaling pathway ptg04081   Hormone signaling ptg04140   Autophagy - animal ptg04152   AMPK signaling pathway ptg04211   Longevity regulating pathway ptg04213   Longevity regulating pathway - multiple species ptg04910   Insulin signaling pathway ptg04920   Adipocytokine signaling pathway ptg04923   Regulation of lipolysis in adipocytes ptg04930   Type II diabetes mellitus ptg04935   Growth hormone synthesis, secretion and action ptg05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102952189 (IRS4)    04022 cGMP-PKG signaling pathway     102952189 (IRS4)    04152 AMPK signaling pathway     102952189 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     102952189 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102952189 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102952189 (IRS4)    04923 Regulation of lipolysis in adipocytes     102952189 (IRS4)    04920 Adipocytokine signaling pathway     102952189 (IRS4)    04935 Growth hormone synthesis, secretion and action     102952189 (IRS4)   09149 Aging    04211 Longevity regulating pathway     102952189 (IRS4)    04213 Longevity regulating pathway - multiple species     102952189 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102952189 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102952189 (IRS4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS Motif Other DBs NCBI-GeneID:  102952189 NCBI-ProteinID:  XP_007091119 LinkDB All DBs Position Un AA seq 1000 aa AA seqDB search MSEQAAETYREQLQSQDSLIIHTHSVSESLFQKPRMFRAPPPFYKDVWQVIVKPRGLGHR KELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGEL WMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLDTLPLE PGGWLRRSRFEQFCHLRAIGDGEDEMLLTRRYLTPSEPVLPSRRGRLHLPRARRSKRAIS VPASFFRRLTPSPVRVPHPVEAPNHGSCLSSEASRPGNSGEEDSPQGKEDQEGNEGDYMP MNNWGSGNGRGSGGGQGSSGQGSSSQSSGGSQCSGGGQGSGGGQGSSGGQGSSGGQGSGG QGAGGNQRAGDGQGTAGGHGSGSGQGAGGGHGSGSGQGSGDGHGSGGGKNSGGGKGPGGG KTPDGSGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPPGATGGKGKSGGRFRLYF CADRGATKERKEAKEVKEADTPEGAARGPHRARAFDEDEDDPYVPMRPGVAAPLASSSDY MLMAPQNFSASKRHSRSPFEDTRGYMMMFPRVSPAPATSSPKEPDPDKDDEARDNDSDSD YMFMAPGAGAIPKNPPNPQGGSSSKSWSSYFSLPNPFQGSPLGQSDHSEYVPMLPGKFLG KGLDKESASNRGPKDAVSKPSVEGSFSKPGDNGPPKNKAKRPNRLSFITKGNKIKPKSQK PTREQREADSSGDYVNIDFTKRDTNMPAPFIQGLPGSWSIIAGPRPSAFSNYVNVEFRVP FPNPAHSLSNLLRAFPGANPLFLEGARWPFVPLPPSATGGNANEEEGDYIEVIFNPAMPP AVPFADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEDGLERRRPQS RSQSFFASARAAVSAFPTDSLETVRGAPGVARGSNPRAPNPDADLARGENGAAAAAPPPP PPRRRVPIPREREDYDDDDDDTYVRMDFARPDNKKFDSPH NT seq 3003 nt NT seq  +upstreamnt  +downstreamnt atgtctgagcaggcagctgaaacatatagggagcagctccagagtcaggactctctgatc atccacactcattctgtctctgagagcctgtttcagaaaccacggatgttccgagcacct ccacccttctataaagatgtgtggcaggtaatagtcaaacccagggggctggggcacaga aaagagctgagcggcgtgttccggctctgtcttaccgacgaggaggttgtctttgtgagg ttgaacaccgaagtggccagcgtggtagtccagctcctgagcatccgtcgctgcgggcac tcagagcagtatttcttcttggaagtcggtaggtccaccgtcatcggtccgggggaactc tggatgcaggtcgatgactgcgtggtggcccaaaacatgcacgagctgtttctggagaag atgagagccctgtgtgcagacgaatacagagcccgctgccgcagctacagcatcagcatc ggcgcccacctgttaaccctgctgtccgctaggaggcacctggacacgctcccactggag cccggtggctggctgagaaggtcccgctttgagcagttttgccacctcagggccatcggt gacggggaagacgagatgctcctcaccaggcgctacctaacacccagcgagcccgtgctc ccctccaggcgaggaagactgcacctgcccagagcgcgcaggtccaagagagcgatttca gtgccagccagcttttttcgccgcttaacacccagtccggtgcgtgtcccgcatcctgta gaagcccccaaccacggatcttgcctgtcctctgaagcatctcgccctggcaactctggg gaagaagacagtcctcagggcaaagaggatcaggaaggaaacgaaggtgactacatgccc atgaacaactggggctcaggaaatggccggggttccggaggtggccagggctcaagtggc caaggctccagtagccagagttcaggaggaagtcagtgctcaggcggagggcagggctcc ggaggtggccagggttcaagtggtggccagggctcaagcggtggccaaggctcagggggc cagggggcaggaggaaaccagcgtgcaggagatggccagggcactgcgggtgggcacggt tcaggcagtggccagggagccggtggtggacacggctcaggcagtgggcagggatctgga gatggtcatggctcaggtggtggcaagaactctggagggggcaaaggcccaggaggtggg aagacccccgatggcagtggtgaacgtggaaaatctctgaagaaaagatcctactttggc aaattaactcaaagcaagcagcagcaaatgccaccacctccacctcctccacctccaccc cctccacctggagcaactggtggtaaagggaagtctgggggaaggttccgactctacttt tgtgccgacagaggagccacaaaagaacgcaaagaagccaaagaagtcaaagaggcagat accccagaaggtgcagctcgggggccccacagagccagagcttttgatgaagatgaagat gacccatatgtgccaatgaggccaggggtggccgcccctctggcaagctccagcgattat atgctgatggctcctcaaaacttctctgcttcaaaacgccactctcgatcaccttttgaa gatacaagagggtacatgatgatgtttcccagagtgagcccagcccctgccacaagttct ccaaaagagcctgatcctgataaggacgacgaggcaagggacaatgacagtgacagtgac tatatgtttatggctcccggagccggcgcaattccaaaaaatcccccaaaccctcagggt ggttcttcctctaaaagttggagctcttacttttctctgccaaatccctttcagggctcc ccattgggacagagtgaccacagtgagtatgtaccaatgttacctggaaaattcctgggg aagggcctagacaaagaatctgcatctaacaggggccccaaagacgcagtttcaaagcct tcagttgaggggtcgttctcaaagcctggagataacggcccccccaagaacaaggctaag agacctaaccgcctttcttttattacaaaaggaaataaaatcaagcccaaatcacaaaaa cccacacgtgagcagagagaagctgacagttctggtgactacgtcaacattgacttcact aagagagatactaatatgccagccccctttattcaaggactgccaggttcgtggagtatc attgctggccccagaccgtcagccttttctaattatgtgaatgttgagttcagagtgcca tttccgaacccagcacacagcctctcgaatctattaagagcttttccaggtgccaacccc ctctttctggaaggtgctaggtggccatttgtgcctcttcctcccagtgctacaggtggc aatgctaatgaggaagagggtgactacatcgaagtgattttcaatccagcaatgccccca gccgtgccttttgctgacagtgccattcgctatgatgctgaaacaggtcgaatctatgtg gtcgacccattttctgagtgctgtatggacatttctctttcccccagccgctgctctgaa ccaccacctgtggctaggctgctgcaggaagacgggctggagcgcagacgcccgcagagc cgttcgcaaagtttctttgcctccgctagagccgctgtctcggctttccccaccgacagc cttgagacggtaaggggggccccaggcgttgcccgtggctcgaacccgagggccccaaac ccagatgcagacctggcccgaggtgagaacggggctgcagcggccgcccccccaccgcca ccaccccgccgccgggtgccgattccccgggagcgagaggattacgacgacgacgacgac gacacatacgtgagaatggactttgccagacctgacaacaagaagttcgactctccccac tga

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