Panthera tigris altaica (Amur tiger): 102955273 Help Entry 102955273         CDS       T02988                                  Symbol FLT1 Name (RefSeq) fms related tyrosine kinase 1   KO K05096   FMS-like tyrosine kinase 1 [EC:2.7.10.1] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg04010   MAPK signaling pathway ptg04014   Ras signaling pathway ptg04015   Rap1 signaling pathway ptg04020   Calcium signaling pathway ptg04066   HIF-1 signaling pathway ptg04151   PI3K-Akt signaling pathway ptg04510   Focal adhesion ptg05202   Transcriptional misregulation in cancer ptg05323   Rheumatoid arthritis Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102955273 (FLT1)    04014 Ras signaling pathway     102955273 (FLT1)    04015 Rap1 signaling pathway     102955273 (FLT1)    04066 HIF-1 signaling pathway     102955273 (FLT1)    04020 Calcium signaling pathway     102955273 (FLT1)    04151 PI3K-Akt signaling pathway     102955273 (FLT1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102955273 (FLT1)  09160 Human Diseases   09161 Cancer: overview    05202 Transcriptional misregulation in cancer     102955273 (FLT1)   09163 Immune disease    05323 Rheumatoid arthritis     102955273 (FLT1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ptg01001]     102955273 (FLT1) Enzymes [BR:ptg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102955273 (FLT1) Protein kinases [BR:ptg01001]  Receptor tyrosine kinases (RTK)   VEGFR family [OT]    102955273 (FLT1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Ig_3 I-set Pkinase VEGFR-1-like_Ig-like Ig_2 ig Ig_VEGFR-1-like_5th V-set VEGFR-2_TMD VEGFR1-3_N_Ig-like C1-set Ig_4 Ig_5 Haspin_kinase Herpes_gE C2-set_2 Motif Other DBs NCBI-GeneID:  102955273 NCBI-ProteinID:  XP_015395764 LinkDB All DBs Position Un AA seq 1377 aa AA seqDB search MELPYRDDADNCLPPTPLAQDLIVFRLAIVLASRGLGPAPSKKGKDCLGRSNSTWEKGKL GSSSGSKLKGPELSLKGSQHIMQAGQTLYLKCRGEAAHSWSLPETVRKESKRLSITKSAC GRNDKQFCSTLTLNMAQANHTGFYSCKYLSTPTSKKKKTESTIYIFINDTDRPFLEMHSE IPEIIYMTEGREVVIPCRVTSPNVTVTLKKFPHDTLIPDGKRITWDSRKGFIIANATYRE IGLLACETTVNGHLYKTNYLTYRQTNTIIDAQISTPSPVKLLRGRTLTLNCTTTTALNTR VQMTWSYPGETKKRASIRQRIGRRSSDANVFYSVLMIDNVQNRDKGLYTCHVKSGPSFKS VNTSVHVYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVLWLKDGFPVTEKSA RYLVLGYSLIIKDVAAEDAGDYTILLAIKQSNVFKNLTTTLIVNVKPQIYEKAVSSFPDP TLYPLGSRQTLTCTIYGIPQPTVRWFWRPCHHNHSKARYDFCSSNDEPLILDPDSNVGNR IESITQRTAIIEGKNKTASTLVVADARISGIYSCVASNKVGTVERNINFYITDVPNGFHV NLEKMPTEGEDLKLSCTVNKFLYTDITWLLLRTVKNRTMHHSISKQKMAITKEYSVTLDL TVKNASLEDSGTYACRARNIYTGEEILQKKEVTIRDQEAPRLLTSLSDRTVAISSSSTFR CLVTGVPEPQITWFKNNHQIQQAPGIILGPGSSTLFLERVTEDDEGAYHCRATNQKGSVE SSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFIRKLKRSSSEIKTDYLSIIMDP DEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVK MLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYL KSKRDLFFLNKDAALHMEPKKEKMEPDPEQDKKQRLDSVTSSESFASSGFQEDKSLSDVE EEEDSDDFYKQPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDF GLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYP GVQMDEDFCSRLKEGIRMRAPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQAN VQQDGKDYIPLNAILTGNSGFSYSSRAFSDDFFKEDISAPQFNSGSSDNVRYVNAFNFLS LERIKTFEELSPNATSIFDDYQMDSGSLLASPLLKRFTWAESKPKASLKIDLRVTSKSKE SGLSDLMRPTVCHPRCGHTSKGRRRFTYDNSELEKKISSCSPPPDYNSVVLYSTPPV NT seq 4134 nt NT seq  +upstreamnt  +downstreamnt atggaactaccataccgcgatgatgctgataactgcttgccacccacgcccttggctcag gacctcatcgtctttcgcctggccattgtcctagcctcccgaggcctgggcccagctccc tccaagaagggaaaagactgccttgggcgctccaactccacatgggagaaaggcaagctg ggatctagttcaggttcgaaattaaaaggtcctgaactgagtttaaaaggctcccagcac atcatgcaagcaggccagacactgtatctcaaatgtagaggggaagcagcccattcatgg tctttgcctgaaacagtgagaaaggaaagcaaaaggctgagcataactaaatctgcctgt ggaaggaatgataaacagttctgcagtactttgaccttgaacatggctcaagcaaaccac actggcttctatagctgcaaatatctatctacacccacttcaaagaagaagaaaacagaa tctacaatctatatatttattaatgatacagatagacctttcttagagatgcacagtgaa atacctgaaattatatatatgactgaaggaagggaggtcgtcatcccctgccgggtcacg tcacctaacgtcactgttactttaaaaaagtttccacatgatacgctgatccctgatgga aaacgaataacctgggacagcaggaagggtttcataatagcaaatgccacatacagagaa atagggcttctggcatgtgaaacaacagtcaacggacatctgtacaagacaaactatctt acctatcgacaaaccaatacaatcatagatgcccaaataagcactccaagcccagtcaag ttgctacgaggtcgcactcttactctcaactgtacaactaccactgccttgaacacaaga gttcaaatgacctggagttatcccggtgaaacaaagaagagagcttctataaggcaacga attggccgacgcagttccgacgctaacgtgttctacagtgttcttatgattgacaatgtg cagaacagagacaaaggactttatacttgtcatgtgaagagtggcccgtcattcaaatct gttaacacctcagtgcacgtatatgataaagcgttcatcactgtgaaacatcgaaaacag caagtgttggaaactgttgctggcaagcggtcttacaggctgtctatgaaagtgaaggca tttccctcgccagaagtcctgtggttaaaagatgggttccctgtgaccgagaaatcggct cgctatttggttcttggctactcattaatcatcaaagacgttgctgcagaagatgcaggg gattacacaatcttgctggccataaagcagtcaaatgtgtttaaaaaccttaccaccacc ttaattgtaaatgtgaaaccccagatttatgaaaaggccgtgtcgtcctttccagacccg accctctaccccttgggcagcagacagaccctgacttgtaccatttatggtatccctcag cctacagtcaggtggttctggcgtccctgtcaccataatcattccaaagcaagatatgac ttctgctccagtaatgatgagcccctgatcctggatcctgacagcaacgtaggaaacagg attgagagcatcacgcagcgcacggcaataatagaaggaaagaataagacggcgagtacc ttggttgtggcggacgctaggatttctggaatctacagttgcgtggcttctaataaagta gggactgtggaaagaaacataaacttttatatcacagacgtgcccaacggatttcacgtt aacttggaaaaaatgccgacggaaggagaggacctgaaactgtcttgcacagttaacaag ttcttatacacagacattacttggcttttgctgcggacagttaaaaaccgcacaatgcat cacagtatcagcaagcaaaaaatggccatcactaaagaatactctgttactctcgatctc accgtcaagaatgcttccctggaagattcaggcacgtatgcctgcagagccaggaacata tacacaggggaagaaatcctccagaagaaagaagttacaattagagatcaggaagcacca cgcctcctgacaagcctcagtgatcgcacagtggccatcagcagctccagcacgttccgc tgtcttgttaccggcgtcccagagcctcagataacctggtttaaaaacaaccaccagata cagcaggcacccggaattatcttaggaccgggaagcagcacgctgtttcttgaaagagtc acagaagacgacgaaggtgcatatcactgcagggccaccaaccagaaggggtctgtggaa agttcggcgtacctcactgttcaaggaacctcggacaagtctaacctggagctaatcact ctgacgtgcacctgtgtggctgcaaccctcttctggctcctgttaacgctctttatccga aaactgaaaaggtcttcctcggaaataaagactgactacctatcgattataatggaccca gacgaagtccccctggacgagcagtgtgagcggctcccttatgatgccagcaagtgggag tttgcccgggagagactcaaactgggcaagtcactcggaagaggggctttcggaaaagtg gttcaagcatccgcatttggcattaagaaatcccccacgtgccggactgtggctgtaaaa atgctgaaagagggggccacggccagcgagtacaaagctctgatgactgagctcaagatc ttgacccacattggccaccatctgaatgtggtcaacctgctgggagcctgtaccaagcaa ggagggcctctgatggtgatcgttgaatattgcaaatacggaaatctgtccaactacctc aagagcaaacgagacttattctttctcaacaaggatgcagcattacacatggagcccaaa aaagaaaaaatggagccagacccggagcaagacaagaaacaaagactagatagtgtcacc agcagtgagagcttcgcaagctctgggtttcaggaagataaaagtctgagtgatgttgag gaagaggaggattccgatgatttctacaagcagcccatcactatggaagatctgatttct tacagttttcaagtggccagaggcatggagttcttgtcttccagaaagtgcattcatcgg gacctggcagcaagaaatattcttttatctgagaacaacgtggtgaagatttgcgatttt ggccttgcccgggatatttataagaaccccgattatgtgagaaaaggagatactcgactt cctctgaaatggatggctcccgaatctatcttcgacaaaatctacagcaccaagagtgac gtgtggtcttacggagtgctgctgtgggaaatcttctccttaggtgggtccccgtacccg ggcgtacaaatggacgaggacttctgcagccgtctgaaggaaggcataaggatgagggcc cccgaatacgcgactcctgaaatctatcagatcatgttggactgctggcacaaagaccca aaagaaaggccaagatttgcagaacttgtggaaaaactaggcgatttgctccaggcaaat gtacaacaggatggtaaagactatatcccactaaatgccatactgacaggaaatagcggg ttttcatactcgtctcgtgccttctctgatgacttcttcaaggaagatatttcagctcca cagtttaattcaggaagttctgataatgtcagatatgtaaatgctttcaatttcttgagc ttggagagaatcaaaacctttgaagaactttcgccaaacgccacctcgatctttgatgat taccagatggacagtggctctctgctggcctcccccttgctgaagcgcttcacctgggct gagagcaaacccaaggcctcactgaagattgacttgagagtaaccagtaaaagtaaggag tcggggctttccgacctcatgcggcctactgtctgccatcccaggtgtgggcacaccagc aaaggcaggcgcaggttcacatacgacaactcagagctggagaagaagatttcgtcctgt tctcctcccccagactacaactcggtggtcctatattccaccccgcctgtctaa

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