Panthera tigris altaica (Amur tiger): 102956490 Help Entry 102956490         CDS       T02988                                  Symbol PRKCG Name (RefSeq) protein kinase C gamma   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism ptg  Panthera tigris altaica (Amur tiger) Pathway ptg01521   EGFR tyrosine kinase inhibitor resistance ptg04010   MAPK signaling pathway ptg04012   ErbB signaling pathway ptg04014   Ras signaling pathway ptg04015   Rap1 signaling pathway ptg04020   Calcium signaling pathway ptg04066   HIF-1 signaling pathway ptg04070   Phosphatidylinositol signaling system ptg04071   Sphingolipid signaling pathway ptg04082   Neuroactive ligand signaling ptg04150   mTOR signaling pathway ptg04270   Vascular smooth muscle contraction ptg04310   Wnt signaling pathway ptg04370   VEGF signaling pathway ptg04510   Focal adhesion ptg04540   Gap junction ptg04613   Neutrophil extracellular trap formation ptg04650   Natural killer cell mediated cytotoxicity ptg04666   Fc gamma R-mediated phagocytosis ptg04670   Leukocyte transendothelial migration ptg04713   Circadian entrainment ptg04720   Long-term potentiation ptg04723   Retrograde endocannabinoid signaling ptg04724   Glutamatergic synapse ptg04725   Cholinergic synapse ptg04726   Serotonergic synapse ptg04727   GABAergic synapse ptg04728   Dopaminergic synapse ptg04730   Long-term depression ptg04750   Inflammatory mediator regulation of TRP channels ptg04911   Insulin secretion ptg04916   Melanogenesis ptg04918   Thyroid hormone synthesis ptg04919   Thyroid hormone signaling pathway ptg04921   Oxytocin signaling pathway ptg04925   Aldosterone synthesis and secretion ptg04928   Parathyroid hormone synthesis, secretion and action ptg04929   GnRH secretion ptg04935   Growth hormone synthesis, secretion and action ptg04960   Aldosterone-regulated sodium reabsorption ptg04961   Endocrine and other factor-regulated calcium reabsorption ptg04970   Salivary secretion ptg04971   Gastric acid secretion ptg04972   Pancreatic secretion ptg05017   Spinocerebellar ataxia ptg05022   Pathways of neurodegeneration - multiple diseases ptg05031   Amphetamine addiction ptg05032   Morphine addiction ptg05143   African trypanosomiasis ptg05146   Amoebiasis ptg05161   Hepatitis B ptg05163   Human cytomegalovirus infection ptg05170   Human immunodeficiency virus 1 infection ptg05171   Coronavirus disease - COVID-19 ptg05200   Pathways in cancer ptg05205   Proteoglycans in cancer ptg05206   MicroRNAs in cancer ptg05207   Chemical carcinogenesis - receptor activation ptg05214   Glioma ptg05223   Non-small cell lung cancer ptg05225   Hepatocellular carcinoma ptg05231   Choline metabolism in cancer ptg05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ptg00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102956490 (PRKCG)    04012 ErbB signaling pathway     102956490 (PRKCG)    04014 Ras signaling pathway     102956490 (PRKCG)    04015 Rap1 signaling pathway     102956490 (PRKCG)    04310 Wnt signaling pathway     102956490 (PRKCG)    04370 VEGF signaling pathway     102956490 (PRKCG)    04066 HIF-1 signaling pathway     102956490 (PRKCG)    04020 Calcium signaling pathway     102956490 (PRKCG)    04070 Phosphatidylinositol signaling system     102956490 (PRKCG)    04071 Sphingolipid signaling pathway     102956490 (PRKCG)    04150 mTOR signaling pathway     102956490 (PRKCG)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102956490 (PRKCG)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102956490 (PRKCG)    04540 Gap junction     102956490 (PRKCG)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     102956490 (PRKCG)    04650 Natural killer cell mediated cytotoxicity     102956490 (PRKCG)    04666 Fc gamma R-mediated phagocytosis     102956490 (PRKCG)    04670 Leukocyte transendothelial migration     102956490 (PRKCG)   09152 Endocrine system    04911 Insulin secretion     102956490 (PRKCG)    04929 GnRH secretion     102956490 (PRKCG)    04921 Oxytocin signaling pathway     102956490 (PRKCG)    04935 Growth hormone synthesis, secretion and action     102956490 (PRKCG)    04918 Thyroid hormone synthesis     102956490 (PRKCG)    04919 Thyroid hormone signaling pathway     102956490 (PRKCG)    04928 Parathyroid hormone synthesis, secretion and action     102956490 (PRKCG)    04916 Melanogenesis     102956490 (PRKCG)    04925 Aldosterone synthesis and secretion     102956490 (PRKCG)   09153 Circulatory system    04270 Vascular smooth muscle contraction     102956490 (PRKCG)   09154 Digestive system    04970 Salivary secretion     102956490 (PRKCG)    04971 Gastric acid secretion     102956490 (PRKCG)    04972 Pancreatic secretion     102956490 (PRKCG)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102956490 (PRKCG)    04961 Endocrine and other factor-regulated calcium reabsorption     102956490 (PRKCG)   09156 Nervous system    04724 Glutamatergic synapse     102956490 (PRKCG)    04727 GABAergic synapse     102956490 (PRKCG)    04725 Cholinergic synapse     102956490 (PRKCG)    04728 Dopaminergic synapse     102956490 (PRKCG)    04726 Serotonergic synapse     102956490 (PRKCG)    04720 Long-term potentiation     102956490 (PRKCG)    04730 Long-term depression     102956490 (PRKCG)    04723 Retrograde endocannabinoid signaling     102956490 (PRKCG)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102956490 (PRKCG)   09159 Environmental adaptation    04713 Circadian entrainment     102956490 (PRKCG)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102956490 (PRKCG)    05206 MicroRNAs in cancer     102956490 (PRKCG)    05205 Proteoglycans in cancer     102956490 (PRKCG)    05207 Chemical carcinogenesis - receptor activation     102956490 (PRKCG)    05231 Choline metabolism in cancer     102956490 (PRKCG)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     102956490 (PRKCG)    05214 Glioma     102956490 (PRKCG)    05223 Non-small cell lung cancer     102956490 (PRKCG)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102956490 (PRKCG)    05161 Hepatitis B     102956490 (PRKCG)    05171 Coronavirus disease - COVID-19     102956490 (PRKCG)    05163 Human cytomegalovirus infection     102956490 (PRKCG)   09174 Infectious disease: parasitic    05146 Amoebiasis     102956490 (PRKCG)    05143 African trypanosomiasis     102956490 (PRKCG)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     102956490 (PRKCG)    05022 Pathways of neurodegeneration - multiple diseases     102956490 (PRKCG)   09165 Substance dependence    05031 Amphetamine addiction     102956490 (PRKCG)    05032 Morphine addiction     102956490 (PRKCG)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102956490 (PRKCG)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102956490 (PRKCG)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ptg01001]     102956490 (PRKCG) Enzymes [BR:ptg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      102956490 (PRKCG) Protein kinases [BR:ptg01001]  Serine/threonine kinases: AGC group   PKC family [OT]    102956490 (PRKCG) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C2 C1_1 Pkinase_C ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  102956490 NCBI-ProteinID:  XP_015395251 LinkDB All DBs Position Un AA seq 675 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCEYSTLAAPGRTWPYTPSLPLSVGEARNLIPMDPNGLSDPYVKLKLIP DPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFG VSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQKFEACNYPLELYERVRMGPSSS PIPSPSPSPTDSKRCFFGTSPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKIL KKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDL MYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMC KENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEE LFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGSGPDGEPAIRAHGFFRWMDWERL ERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFVH PDARSPVSPPPVPVM NT seq 2028 nt NT seq  +upstreamnt  +downstreamnt atggcaggcctgggccccggcggaggcgattcagaggggggaccccggcccctgttttgc agaaagggggccctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgcc cgcttcttcaagcagccaaccttctgcagccactgcacagacttcatctggggcattggg aaacaaggcctgcaatgtcaagtttgcagctttgtggttcatcgacgatgccacgaattt gtgaccttcgagtgtccaggcgctgggaagggcccccagacggatgacccccggaacaag cacaagttccgtctgcacagctacagcagccccaccttctgcgaccactgtggctccctt ctttatgggctggtgcaccagggcatgaaatgctcctgtgagtactccacgcttgctgct cctggccgaacctggccctacaccccttcacttcctctctcagttggcgaggcccgtaac cttatcccaatggaccccaatggtctgtctgacccctacgtgaagctgaagctcatccca gaccctcggaacttgacaaagcaaaagacccggaccgtgaaagccacgctaaaccctgtg tggaacgagacctttgtgttcaacctgaagccaggagacgtggagcgcaggcttagcgtg gaggtgtgggactgggaccggacttcccgcaacgatttcatgggcgccatgtccttcggg gtctcggagctgctcaaggcacctgtggacggctggtacaagttactgaaccaggaggag ggcgaatattacaatgtgccagtggctgatgctgacaactgcagcctcctccagaagttt gaggcctgtaactaccccctggaactgtacgagcgggtgcggatgggtccctcttcctct cccatcccctccccatcccctagtcccacggactccaaacgctgtttctttgggacaagc cctggacgtctgcacatctctgacttcagcttcctcatggttctaggaaaaggcagcttt gggaaggtgatgctggctgagcgcaggggctctgatgagctctacgccatcaagatcctg aagaaagacgtgatcgtccaggatgatgatgtggactgcaccctggtggagaagcgcgtg ctggccctggggggccgaggcccgggaggccggccccactttctcacccagctgcactcc accttccagaccccggaccgtctgtattttgtgatggagtatgtcaccgggggcgacctg atgtaccacatccagcaattgggcaagtttaaggagccccatgcagcgttctacgcagca gaaatcgccatcggcctcttcttccttcacaatcagggcatcatctaccgggacctgaaa ttagacaacgtgatgctggatgctgaaggacacatcaaaatcactgactttggcatgtgt aaggagaacgtcttccctgggaccaccacccgcaccttctgtgggaccccagactacata gctcctgagatcattgcctaccaaccctatggaaagtctgttgattggtggtcctttggg gttctgttgtatgagatgttggcaggacagccccctttcgatggggaggatgaggaagag ctgtttcaggctatcatggaacaaaccgtcacttaccccaagtcactttcccgggaagct gtggccatctgcaaggggttcctaactaagcacccagcgaaacgcctgggctcagggccg gacggggagcccgccatccgtgctcatggctttttccgctggatggactgggagcggctg gaacgactggagatcgcgcctccgttcagaccccgtccgtgtggacgcagcggcgagaac ttcgacaagttctttacgcgggcggcgccagcgttgacccccccagaccgccttgttctg gccagcatcgaccaggccgatttccaaggcttcacctacgtgaacccggatttcgtgcac cccgacgcccgcagccccgtcagcccgccgccggtgccagtcatgtaa

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