Panthera tigris altaica (Amur tiger): 102963505
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Entry
102963505 CDS
T02988
Symbol
ITCH
Name
(RefSeq) itchy E3 ubiquitin protein ligase
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04120
Ubiquitin mediated proteolysis
ptg04144
Endocytosis
ptg04330
Notch signaling pathway
ptg04668
TNF signaling pathway
ptg04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102963505 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102963505 (ITCH)
04668 TNF signaling pathway
102963505 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102963505 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102963505 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ptg04131
]
102963505 (ITCH)
04121 Ubiquitin system [BR:
ptg04121
]
102963505 (ITCH)
Enzymes [BR:
ptg01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102963505 (ITCH)
Membrane trafficking [BR:
ptg04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102963505 (ITCH)
Ubiquitin system [BR:
ptg04121
]
Ubiquitin ligases (E3)
HECT type E3
102963505 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102963505
NCBI-ProteinID:
XP_007073651
UniProt:
A0A8C9J2R5
LinkDB
All DBs
Position
Un
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETMGDLSVCLDGLQLESEVVTNGETTCSESASQNDDGSRPKDEARTNPNGS
DEPEDSGTGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNTVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcgcagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcacccctgtgagtaaattgcat
tttcgcgtgtggagtcatcagacactgaaatctgatgttttgttgggaactgcagcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagagacaatgggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctctagacccaaggatgaagcaagaacaaatccaaatggatca
gatgaacctgaggattcagggactggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctccg
cctaccccacgtagaccagcatctgtcaatggttcaccatctgctacttctgaaagtgat
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
actgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcatgggcga
gtttactacgtagatcatattgaaaaaagaacaacgtgggacagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccgacattggaatctgtccggaactatgaacagtggcaa
ctccaacgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaggatttgtttactacatcgcaaaataaagaatttgatccccttggtcccctgcct
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaggaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtagatggaattccatattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgctctagacaatggaccacag
atagcctacgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggcaatgccacagcacataaagattacagtgacaagaaaaacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
cacgaggtgttgaaccccatgtattgcctgtttgaatatgcaggaaaggataactactgc
ctgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctttgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacttgtcgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaactggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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