Panthera tigris altaica (Amur tiger): 102966280
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Entry
102966280 CDS
T02988
Symbol
JAK3
Name
(RefSeq) Janus kinase 3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04062
Chemokine signaling pathway
ptg04151
PI3K-Akt signaling pathway
ptg04217
Necroptosis
ptg04550
Signaling pathways regulating pluripotency of stem cells
ptg04630
JAK-STAT signaling pathway
ptg04658
Th1 and Th2 cell differentiation
ptg04659
Th17 cell differentiation
ptg05161
Hepatitis B
ptg05162
Measles
ptg05166
Human T-cell leukemia virus 1 infection
ptg05169
Epstein-Barr virus infection
ptg05200
Pathways in cancer
ptg05203
Viral carcinogenesis
ptg05223
Non-small cell lung cancer
ptg05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102966280 (JAK3)
04151 PI3K-Akt signaling pathway
102966280 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102966280 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102966280 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102966280 (JAK3)
04659 Th17 cell differentiation
102966280 (JAK3)
04062 Chemokine signaling pathway
102966280 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102966280 (JAK3)
05203 Viral carcinogenesis
102966280 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
102966280 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102966280 (JAK3)
05161 Hepatitis B
102966280 (JAK3)
05162 Measles
102966280 (JAK3)
05169 Epstein-Barr virus infection
102966280 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
102966280 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102966280 (JAK3)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102966280 (JAK3)
Protein kinases [BR:
ptg01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102966280 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F1
SH2_1
Motif
Other DBs
NCBI-GeneID:
102966280
NCBI-ProteinID:
XP_007088709
LinkDB
All DBs
Position
Un
AA seq
815 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSYWYPPSHIFSVEDASTQVLLYRLRFYFPNWFGLEKCHRFGL
RKDLASAVLDLPGLEHLFAQGGVRMGLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTV
CVQTPLGPDYKGCLIRCDPSGTFSLAGLGRPHSSLRELLAACWDAGLHVDGVALNLTSCC
APRPKEKSNLIVVRRGCSAPTSSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKI
YRGCRHEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGD
SVMVQEFVRLGALDTYLRKSGPLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLL
AREGADGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATV
WEVFSGIPMPISTLDPAKKLQFYEERQHLPAPKWMELATLIQQCMAYEPGQRPSFRAIIR
DLNSLITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGS
VELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPDH
GLPISRPSLPHNLVPPRSAPLSWPLSLEPRLSALSPPRPPFGYAPESLSDNIFSRQSDVW
SFGVVLYELFTYGSKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVH
ELMKLCWAPSPQDRPTFSALGPQLDTLWSGSRGVA
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctccaagtgaggagacacccctgatccctcagcgttcctgcagcctctcatct
tcagaggctggtgccctgcacgtgctgctgccccctcggggacccggacccccacaacgc
ctgtccttctcctttggggaccattcagctgaagagctatgtgtttgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctac
tggtaccccccgagccacatcttctccgtggaggatgcaagcacccaagtcctgctctac
aggctccgcttttacttccccaactggtttgggttggagaaatgccaccgcttcgggctg
cggaaggacttggccagtgccgtccttgacctgccaggcctggagcatctcttcgcccag
ggaggggtccgcatgggcctggattttgccatcaacaagctcaagaccgggggctccctt
cccggctcctatgttctccgccgcagcccccaggatttcgacagcttcctcctcactgtc
tgcgtccagacccccctgggtcctgattacaagggctgcctcatccggtgtgacccctcg
ggaaccttctccctggctggcctcggccggccccacagcagtcttcgagagctcttggca
gcctgctgggatgctgggctgcacgtggatggggttgcgctgaacctcacctcctgctgc
gcccccagacccaaagaaaagtccaacctgatcgtggtgcggagaggttgcagcgctccc
acgtcatcccttgtttggccccaatcccagtgccagctgagtcagatgacgtttcacaag
atccctgctgacagcctggagtggcatgagaacctgggtcatgggtccttcaccaagatt
taccgaggttgtcgccatgaggctgtggacggggaagcccgggagacagaggtgctactc
aaagtgatggatgccaagcacagaaactgcatggagtccttcctggaagcagcgagcctg
atgagccaagtgtcgtatcagcacctcgtgttgctccacggcgtgtgcatggctggagac
agtgtcatggtgcaggaattcgtgcgcctgggagccctggatacatatctgcgcaagtct
ggccccctggtaccagccagctggaagctgcaggtgatcaaacagctggcctatgccctc
aactatctggaagacaaaggcctcccccatggcaatgtctcagcccggaaggtgctcttg
gctcgggagggggctgacgggaacctgcccttcatcaagttgagtgaccctggtgtcagc
cccactgtgctgagcctggagatgctcactgacaggatcccctgggtggcccctgagtgt
ctccaggaggcccggacccttggcttggaagctgacaagtggggtttcggtgccacagtc
tgggaagtgttcagcgggatcccgatgcccatcagtaccctggatcctgccaagaagctc
cagttttacgaggaacggcagcaccttcctgcccccaagtggatggagctggctacactg
atccaacagtgcatggcctatgagccaggccagaggccctccttccgcgccatcatccgt
gacctgaacagcctcatcacttcagattatgagctcctctcagaccccacacctggtgcc
ttggcgccccgtgatgggctgtggaatggcgcccagctctacgcctgccaggaccctacc
atttttgaggagaggcatctcaagtacatctcacagctgggcaagggcaactttggcagt
gtggagctgtgccgctatgacccgctgggcgacaacacgggcgccctagtggctgtgaag
cagcttcagcacagcgggccagaccagcagagggacttccagcgggagatccagatcctc
aaagccctccacagcgacttcattgtcaagtaccgcggtgtcagctatggcccggaccac
ggccttcctatcagcagaccctcccttccgcacaacctggtcccacctcgctccgcccct
ctgtcctggcccctctccctggagccacggctctccgccctgagcccgcccagacccccc
tttgggtatgccccagagtccctctctgacaacatcttctcgcgccagtcggacgtctgg
agcttcggggtcgtcctgtacgagcttttcacctacggcagcaagaactgcagcccctca
gccgagttcctccgtatgatgggatgtgagcgagacgtccccgccctctgccgcctcctg
gagctgctggctgagggccagaggctgcccgcgcctcccgcctgccccggtgaggttcat
gagctcatgaagctgtgctgggccccgagcccgcaagaccggccaacattcagtgccctg
ggcccccagctggatacactgtggagtggaagccggggggtagcatag
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