Providencia stuartii 2017-45-35: OI982_14725
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Entry
OI982_14725 CDS
T09168
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ptha
Providencia stuartii 2017-45-35
Pathway
ptha00270
Cysteine and methionine metabolism
ptha00450
Selenocompound metabolism
ptha00670
One carbon pool by folate
ptha01100
Metabolic pathways
ptha01110
Biosynthesis of secondary metabolites
ptha01230
Biosynthesis of amino acids
ptha04981
Folate transport and metabolism
Module
ptha_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ptha00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
OI982_14725 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
OI982_14725 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
OI982_14725 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
OI982_14725 (metH)
04980 Cobalamin transport and metabolism
OI982_14725 (metH)
Enzymes [BR:
ptha01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
OI982_14725 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
WIJ76078
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Position
3043908..3047573
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AA seq
1221 aa
AA seq
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MLEQELQKRILVLDGAMGTMIQRHKLTEEQFRGERFADWPCDLKGNNDLLVLTQPEIIRD
IHDQYFAAGADIVETNTFNSTTIAMADYKMESLSAEINEAAARIARECADEWTRKTPEQP
RYVAGVLGPTNRTASISPDVNDPAFRNINFDQLVEAYRESTRALIKGGVDLIMIETIFDT
LNAKAAIFAVETEFEALGVTLPVMISGTITDASGRTLSGQTTEAFYNSLRHARPLSFGLN
CALGPNELRQYVSELSRIAECYVSAHPNAGLPNAFGEYDLDAQNMAEQIREWAQAGFLNI
VGGCCGTTPLHIKKIVEAVKGIAPRALPKLPVECRLSGLEPLNIGKDSLFVNVGERTNVT
GSAKFKRLIKEGNYQEALDIARQQVENGAQIIDINMDEGMLDSEAAMVRFLNLIAGEPDI
ARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGESAFIEHAKLVRKYGAAVIVMAFD
EVGQADTRERKIEICRRAYHVLTDTVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEVC
QDIKQQLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYD
DLPKELKDAVEDVILNRREDSTERLLELAEKYRASGSEEQQVQQAEWRSWAVEKRLEYAL
VKGITEFIIPDTEEARQLAASPIEVIEGPLMNGMNVVGDLFGEGKMFLPQVVKSARVMKQ
AVAYLEPYIQALKQSGSSAGKILLATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPCE
TILKTAREQNVDVIGLSGLITPSLDEMVHVAKEMERQGFTIPLMIGGATTSKAHTAVKIE
PNYSHSVTYVQNASRTVGVVSALLSATQKAEFVARTRREYEIVREQHGRKKPKTPPVSLE
IARANSVKIDWQNYQPPVPRFLGVKEVKASIETLRHYIDWTPFFMTWSLAGKYPRILEDE
VVGEEARKLLKDANNMLDQLAKDNALTPRGIFGLFPANSVGDDIEIYRSSARDSADVIAL
NLRQQTEKKEFPNYCLSDFVAPKASGKADYIGAFAVTGGLEEDALADGYEQQHDDYNKIM
LKALADRLAEAFAEYLHQQVRKEYWGYAPDEDLPNDELIREKYQGIRPAPGYPACPEHTE
KAKIWQLLDVENQVGMQLTSSYAMWPGASVSGWYFSHPESKYFAVAQVQRDQVEDYAKRK
GMSVSELERWLAPNLGYDPED
NT seq
3666 nt
NT seq
+upstream
nt +downstream
nt
atgttagaacaagaattacaaaaaaggatcttagtactggatggcgcaatggggacgatg
atccagcgccataagctaaccgaagaacaattccgtggtgaacgctttgcggattggcct
tgtgacctcaaaggaaacaacgacctccttgttttgactcagcctgaaattatccgcgat
attcatgatcaatactttgcggctggggcagatattgttgagacaaacacatttaactca
acaacgattgcgatggcagactacaaaatggaatcgttgtctgccgaaataaatgaagcc
gctgcacgtatcgcccgtgaatgtgccgatgagtggacacgtaaaacaccggaacagcca
cgctatgttgctggtgtgttgggaccgactaaccgcacagcctcgatctcccctgatgtt
aacgaccccgcatttcggaatatcaattttgatcaattagttgaagcctatcgtgaatca
acgcgcgccttgatcaaaggaggtgtcgatctgatcatgatcgaaacaatttttgatacg
ttaaatgcaaaagcggcgatctttgcggttgaaacagaatttgaagccttgggagtgact
ctgccagttatgatttcggggacgatcaccgatgcgtctgggcgtaccctatcggggcaa
actaccgaagctttctataactcattgcgtcatgctagacctttatcctttggtctcaac
tgtgctttagggccaaatgaattgcgccaatatgtgtctgaactatcgcgtattgcggag
tgctatgtcagtgcacaccctaacgcaggcttacccaatgcttttggcgaatatgatctc
gatgcacaaaatatggcggaacaaattcgtgaatgggcacaagcaggctttttgaatatt
gtcgggggatgttgtggtacgacaccgttgcacatcaaaaaaattgttgaagccgttaaa
ggaattgcgccgcgcgccttaccaaagttacctgtagagtgccgtttatcagggctagaa
ccacttaatattggcaaagactcgttatttgttaacgtcggcgaacgtacgaatgtgacg
ggatcggcgaagtttaaacgtctcattaaggaaggaaactaccaagaggcattagatatt
gctcgccagcaagtggaaaacggcgcacagattatcgatatcaacatggatgaagggatg
ttggattcggaagcggcgatggtgcgttttcttaatttaattgctggcgaacctgatatt
gcccgtgttcccattatgatcgactcttcaaaatgggatgttatcgaaaaagggctgaaa
tgcattcaaggcaaaggcattgtgaactcaatttcgatgaaggagggggaaagtgccttt
atcgaacatgccaaattggtgcgtaaatatggtgccgcagtcattgtgatggcatttgat
gaggtaggccaagccgacacccgtgaacgaaaaatcgaaatttgtcgtcgtgcctatcac
gtattgactgacacggtcggtttccctccagaagatattatttttgatccaaatattttt
gccgtcgcgacaggtattgaagaacataataactatgctgtcgattttattgaagtttgt
caggatattaagcagcagcttccacatgcgatgatctctggtggtgtctctaacgtgtcg
ttttcattcagaggcaatgatcccgttcgtgaagcgatccatgctgtgttcctctattat
gctatccgtaatggcatggatatggggatcgtcaatgcggggcagttagctatctatgat
gatctgcctaaagagttaaaagatgcggtcgaagatgtgatcttaaaccgccgtgaggat
agcactgaacgcctgttggaattagcggaaaaatatcgtgcatcaggcagtgaggagcag
caagttcaacaggctgaatggcgctcttgggctgtcgaaaagcgtttagaatatgcgtta
gttaaagggatcaccgaatttatcatcccagatacggaggaggcgcgccaactcgcagca
agccctattgaagtgattgaaggaccattgatgaatgggatgaatgtcgtgggtgacttg
tttggtgaagggaaaatgtttttaccacaggttgttaaatccgctcgagtgatgaaacaa
gcagttgcctacttagaaccttatattcaggcacttaaacaatcaggtagcagcgcgggt
aaaattttattagcgaccgttaaaggtgatgttcacgatataggtaaaaatattgtcggc
gtcgttttacagtgtaataactatgagattgttgacttgggcgtgatggtaccttgtgaa
accatcttaaaaacagcccgtgagcagaatgttgatgttattggcctttctgggttaatt
acgccttcgttggatgagatggtccatgtggctaaagagatggagcgccaaggctttaca
atccctttgatgattgggggagcgacaacatcaaaagctcacacggcagtaaaaatagaa
cccaattacagccactcagtgacatatgtacaaaatgcatcgcgcactgtaggcgtggtt
tccgcgctactttccgcaacacaaaaagcggagttcgttgctcgaactcgccgtgaatat
gaaatcgttcgtgagcaacatggacgtaaaaaacccaaaaccccgccagtctcccttgaa
attgctcgcgctaactcagtgaaaattgattggcaaaattaccagccacctgtgccacgt
ttccttggtgtgaaagaggtcaaagcatcgattgagacattacgtcattatattgattgg
acgcctttctttatgacatggtcgctcgcggggaaatatccacgcatcctagaagatgag
gtggtcggtgaagaggcgcgtaaattactaaaagacgcgaacaacatgctagatcaactc
gcgaaggataatgccctgacgccaagaggcatatttggtctatttcctgcaaacagtgta
ggggatgatattgaaatatatcgttcctcggctcgtgatagtgcagatgttatcgctctc
aacctacgtcaacaaacagagaagaaagagtttcctaactactgtttatctgactttgtc
gcccctaaagccagtggaaaagcggattatattggtgcttttgcggttacgggggggtta
gaagaagatgcccttgcagatggatatgaacagcaacatgatgactataataaaattatg
ttgaaggcgttagctgataggcttgcggaggcatttgcggaatacttgcaccagcaggtg
agaaaagagtattggggttatgcccctgacgaggatttgccgaatgatgagctgatccgt
gaaaaatatcaggggatccgaccggcgccggggtatccagcttgccctgaacataccgaa
aaagccaaaatttggcagttattagatgtggaaaatcaagtcggtatgcaattaaccagt
tcttatgcaatgtggcctggagcgtcggtttcaggttggtatttcagccaccctgaaagt
aaatattttgccgtcgctcaggtgcagcgggatcaggtcgaggactatgcaaaacgtaag
ggaatgtcagtcagtgaacttgaaagatggctcgcaccaaatttaggctatgacccagag
gattga
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