KEGG   Providencia stuartii 2017-45-35: OI982_14725
Entry
OI982_14725       CDS       T09168                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ptha  Providencia stuartii 2017-45-35
Pathway
ptha00270  Cysteine and methionine metabolism
ptha00450  Selenocompound metabolism
ptha00670  One carbon pool by folate
ptha01100  Metabolic pathways
ptha01110  Biosynthesis of secondary metabolites
ptha01230  Biosynthesis of amino acids
ptha04981  Folate transport and metabolism
Module
ptha_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ptha00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    OI982_14725 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    OI982_14725 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    OI982_14725 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    OI982_14725 (metH)
   04980 Cobalamin transport and metabolism
    OI982_14725 (metH)
Enzymes [BR:ptha01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     OI982_14725 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: WIJ76078
LinkDB
Position
3043908..3047573
AA seq 1221 aa
MLEQELQKRILVLDGAMGTMIQRHKLTEEQFRGERFADWPCDLKGNNDLLVLTQPEIIRD
IHDQYFAAGADIVETNTFNSTTIAMADYKMESLSAEINEAAARIARECADEWTRKTPEQP
RYVAGVLGPTNRTASISPDVNDPAFRNINFDQLVEAYRESTRALIKGGVDLIMIETIFDT
LNAKAAIFAVETEFEALGVTLPVMISGTITDASGRTLSGQTTEAFYNSLRHARPLSFGLN
CALGPNELRQYVSELSRIAECYVSAHPNAGLPNAFGEYDLDAQNMAEQIREWAQAGFLNI
VGGCCGTTPLHIKKIVEAVKGIAPRALPKLPVECRLSGLEPLNIGKDSLFVNVGERTNVT
GSAKFKRLIKEGNYQEALDIARQQVENGAQIIDINMDEGMLDSEAAMVRFLNLIAGEPDI
ARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGESAFIEHAKLVRKYGAAVIVMAFD
EVGQADTRERKIEICRRAYHVLTDTVGFPPEDIIFDPNIFAVATGIEEHNNYAVDFIEVC
QDIKQQLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYD
DLPKELKDAVEDVILNRREDSTERLLELAEKYRASGSEEQQVQQAEWRSWAVEKRLEYAL
VKGITEFIIPDTEEARQLAASPIEVIEGPLMNGMNVVGDLFGEGKMFLPQVVKSARVMKQ
AVAYLEPYIQALKQSGSSAGKILLATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPCE
TILKTAREQNVDVIGLSGLITPSLDEMVHVAKEMERQGFTIPLMIGGATTSKAHTAVKIE
PNYSHSVTYVQNASRTVGVVSALLSATQKAEFVARTRREYEIVREQHGRKKPKTPPVSLE
IARANSVKIDWQNYQPPVPRFLGVKEVKASIETLRHYIDWTPFFMTWSLAGKYPRILEDE
VVGEEARKLLKDANNMLDQLAKDNALTPRGIFGLFPANSVGDDIEIYRSSARDSADVIAL
NLRQQTEKKEFPNYCLSDFVAPKASGKADYIGAFAVTGGLEEDALADGYEQQHDDYNKIM
LKALADRLAEAFAEYLHQQVRKEYWGYAPDEDLPNDELIREKYQGIRPAPGYPACPEHTE
KAKIWQLLDVENQVGMQLTSSYAMWPGASVSGWYFSHPESKYFAVAQVQRDQVEDYAKRK
GMSVSELERWLAPNLGYDPED
NT seq 3666 nt   +upstreamnt  +downstreamnt
atgttagaacaagaattacaaaaaaggatcttagtactggatggcgcaatggggacgatg
atccagcgccataagctaaccgaagaacaattccgtggtgaacgctttgcggattggcct
tgtgacctcaaaggaaacaacgacctccttgttttgactcagcctgaaattatccgcgat
attcatgatcaatactttgcggctggggcagatattgttgagacaaacacatttaactca
acaacgattgcgatggcagactacaaaatggaatcgttgtctgccgaaataaatgaagcc
gctgcacgtatcgcccgtgaatgtgccgatgagtggacacgtaaaacaccggaacagcca
cgctatgttgctggtgtgttgggaccgactaaccgcacagcctcgatctcccctgatgtt
aacgaccccgcatttcggaatatcaattttgatcaattagttgaagcctatcgtgaatca
acgcgcgccttgatcaaaggaggtgtcgatctgatcatgatcgaaacaatttttgatacg
ttaaatgcaaaagcggcgatctttgcggttgaaacagaatttgaagccttgggagtgact
ctgccagttatgatttcggggacgatcaccgatgcgtctgggcgtaccctatcggggcaa
actaccgaagctttctataactcattgcgtcatgctagacctttatcctttggtctcaac
tgtgctttagggccaaatgaattgcgccaatatgtgtctgaactatcgcgtattgcggag
tgctatgtcagtgcacaccctaacgcaggcttacccaatgcttttggcgaatatgatctc
gatgcacaaaatatggcggaacaaattcgtgaatgggcacaagcaggctttttgaatatt
gtcgggggatgttgtggtacgacaccgttgcacatcaaaaaaattgttgaagccgttaaa
ggaattgcgccgcgcgccttaccaaagttacctgtagagtgccgtttatcagggctagaa
ccacttaatattggcaaagactcgttatttgttaacgtcggcgaacgtacgaatgtgacg
ggatcggcgaagtttaaacgtctcattaaggaaggaaactaccaagaggcattagatatt
gctcgccagcaagtggaaaacggcgcacagattatcgatatcaacatggatgaagggatg
ttggattcggaagcggcgatggtgcgttttcttaatttaattgctggcgaacctgatatt
gcccgtgttcccattatgatcgactcttcaaaatgggatgttatcgaaaaagggctgaaa
tgcattcaaggcaaaggcattgtgaactcaatttcgatgaaggagggggaaagtgccttt
atcgaacatgccaaattggtgcgtaaatatggtgccgcagtcattgtgatggcatttgat
gaggtaggccaagccgacacccgtgaacgaaaaatcgaaatttgtcgtcgtgcctatcac
gtattgactgacacggtcggtttccctccagaagatattatttttgatccaaatattttt
gccgtcgcgacaggtattgaagaacataataactatgctgtcgattttattgaagtttgt
caggatattaagcagcagcttccacatgcgatgatctctggtggtgtctctaacgtgtcg
ttttcattcagaggcaatgatcccgttcgtgaagcgatccatgctgtgttcctctattat
gctatccgtaatggcatggatatggggatcgtcaatgcggggcagttagctatctatgat
gatctgcctaaagagttaaaagatgcggtcgaagatgtgatcttaaaccgccgtgaggat
agcactgaacgcctgttggaattagcggaaaaatatcgtgcatcaggcagtgaggagcag
caagttcaacaggctgaatggcgctcttgggctgtcgaaaagcgtttagaatatgcgtta
gttaaagggatcaccgaatttatcatcccagatacggaggaggcgcgccaactcgcagca
agccctattgaagtgattgaaggaccattgatgaatgggatgaatgtcgtgggtgacttg
tttggtgaagggaaaatgtttttaccacaggttgttaaatccgctcgagtgatgaaacaa
gcagttgcctacttagaaccttatattcaggcacttaaacaatcaggtagcagcgcgggt
aaaattttattagcgaccgttaaaggtgatgttcacgatataggtaaaaatattgtcggc
gtcgttttacagtgtaataactatgagattgttgacttgggcgtgatggtaccttgtgaa
accatcttaaaaacagcccgtgagcagaatgttgatgttattggcctttctgggttaatt
acgccttcgttggatgagatggtccatgtggctaaagagatggagcgccaaggctttaca
atccctttgatgattgggggagcgacaacatcaaaagctcacacggcagtaaaaatagaa
cccaattacagccactcagtgacatatgtacaaaatgcatcgcgcactgtaggcgtggtt
tccgcgctactttccgcaacacaaaaagcggagttcgttgctcgaactcgccgtgaatat
gaaatcgttcgtgagcaacatggacgtaaaaaacccaaaaccccgccagtctcccttgaa
attgctcgcgctaactcagtgaaaattgattggcaaaattaccagccacctgtgccacgt
ttccttggtgtgaaagaggtcaaagcatcgattgagacattacgtcattatattgattgg
acgcctttctttatgacatggtcgctcgcggggaaatatccacgcatcctagaagatgag
gtggtcggtgaagaggcgcgtaaattactaaaagacgcgaacaacatgctagatcaactc
gcgaaggataatgccctgacgccaagaggcatatttggtctatttcctgcaaacagtgta
ggggatgatattgaaatatatcgttcctcggctcgtgatagtgcagatgttatcgctctc
aacctacgtcaacaaacagagaagaaagagtttcctaactactgtttatctgactttgtc
gcccctaaagccagtggaaaagcggattatattggtgcttttgcggttacgggggggtta
gaagaagatgcccttgcagatggatatgaacagcaacatgatgactataataaaattatg
ttgaaggcgttagctgataggcttgcggaggcatttgcggaatacttgcaccagcaggtg
agaaaagagtattggggttatgcccctgacgaggatttgccgaatgatgagctgatccgt
gaaaaatatcaggggatccgaccggcgccggggtatccagcttgccctgaacataccgaa
aaagccaaaatttggcagttattagatgtggaaaatcaagtcggtatgcaattaaccagt
tcttatgcaatgtggcctggagcgtcggtttcaggttggtatttcagccaccctgaaagt
aaatattttgccgtcgctcaggtgcagcgggatcaggtcgaggactatgcaaaacgtaag
ggaatgtcagtcagtgaacttgaaagatggctcgcaccaaatttaggctatgacccagag
gattga

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