KEGG   Phaeodactylum tricornutum: PHATRDRAFT_23399
Entry
PHATRDRAFT_23399  CDS       T01075                                 
Symbol
METH
Name
(RefSeq) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
pti  Phaeodactylum tricornutum
Pathway
pti00270  Cysteine and methionine metabolism
pti00450  Selenocompound metabolism
pti00670  One carbon pool by folate
pti01100  Metabolic pathways
pti01110  Biosynthesis of secondary metabolites
pti01230  Biosynthesis of amino acids
pti04980  Cobalamin transport and metabolism
pti04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:pti00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    PHATRDRAFT_23399 (METH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    PHATRDRAFT_23399 (METH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    PHATRDRAFT_23399 (METH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    PHATRDRAFT_23399 (METH)
   04980 Cobalamin transport and metabolism
    PHATRDRAFT_23399 (METH)
Enzymes [BR:pti01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     PHATRDRAFT_23399 (METH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding MtrH
Other DBs
NCBI-GeneID: 7198319
NCBI-ProteinID: XP_002184461
JGI: 23399
UniProt: B7GBG7
LinkDB
Position
23:complement(421969..428366)
AA seq 1245 aa
MGTMIQNYAKKNRLDEEEYRGERFRDWNCAVKGNNDMLSISQPHIIKGIYMQYLEEGGSN
MIGTNTFSSTTIAMADYQMEAYAYELNYVGARLAREACDEVTAKDPSKPRFVVGAIGPTN
RTCSISPSVEDPAARNVTFDELVETYLEQVVGLVDGGADVLMVETIFDTLNAKAALYAIG
EFLEFSGLDIPVFVSGTLVDQSGRTLSGQTGEAFYVSIRHAKPMCVGLNCALGAKHMVPF
VERLSKAAECFVHVYSNAGLPNAMGGYDDTPEDMARENEVFFENGWLNMVGGCCGSTPPH
IKAIRETAERYQPRKLPDVGRPKMWLSGLEDLKVEDVHNQLGLPFLNVGERCNIAGSIKF
KKLMMKGDYGAAMDIAKQQVEDGAHVIDINVDDGMLDGLAAMQKFVKIAVTEPEIAKVPF
MLDASKFDIVMAGLKWCQGKCIVNSISLKVGEELFMEQATLLKKHGAAVVVMAFDEQGQA
ATEDEKIRICKRSYDVLVNKVGFPPEDIVFDPNVLTIGTGMEEHANYGVDFINSVKRIKE
ECPYVKISGGISNLSFGFRGVTKIRESIHAVFLHHAITESGMDVGIVNSHELLSVDDLEP
DMKLLCENLVFNKTPDATDDMLERTNFERSKGGVVDEVKKSSWRDLEPSKRLEHSLVNGI
SEFVDSDVEEARVLATKPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAY
LLPFMDAEKRENMIAAGLDPDDVDPDDDSNYAGKVLMATVKGDVHDIGKNIVAVVLGCNN
YKVYDIGVMCSCEKILAKAKEYNVDVIGLSGLITPSLDEMVDVAKEMSKQGFKQPLLIGG
ATTSKMHTSVKIAPSYTTPEHPTIHVLDASRSVTVVNSLLGENKGEFVEDIMEEYEEMRE
DYYAGLEDRNFLTFEKAKEQKITINFDQSPVADTPNKIGITVIDTVKISAVVPYIDWNPF
FQTWELRGRYPNRGYPKIFNDEAVGGEAKKLFHDAQTMLNQICEDGSMTLKGVVGIFPAN
RSEDGEDVHVYETEADRESGNVSTTFCMLRQQAEKESDDPYLSQADFVAPAGYKDHLGMF
AVSCFGCDALVKKFESENDDYSKIMAQALADRFVEAFAEYVHREMRLDLWGYAAGEQLNE
SDLLKVKYDGIRPAPGYPSQPDHTEKRTMWNLLQAQELAGIELSESLSMMPASSVSALVF
AHPESEYFAVGQVGKDQVTNYASRKQMDLALCERWLSPILNYERD
NT seq 3738 nt   +upstreamnt  +downstreamnt
atgggcaccatgatccagaactacgccaagaagaaccgactagacgaggaagagtaccgg
ggcgagcgattccgcgactggaactgcgccgtcaagggcaacaacgacatgctcagcatc
tcgcagccccacatcatcaagggtatctacatgcagtacctggaagagggcggcagcaac
atgattgggaccaacacgttttcctccaccaccattgctatggcggactaccagatggaa
gcgtacgcgtacgagctgaactacgtgggcgctcggttggcgcgggaggcctgcgatgaa
gtgacggccaaagaccctagtaagccgcgtttcgtggtgggagccattggacccacgaat
cgtacgtgttcgatctcgccgtcggtggaggaccccgcggcacgcaacgtgacgtttgac
gagctggtagagacgtacctggagcaggtggtgggtctggtggacggcggtgccgacgtg
ctcatggtggagaccatcttcgacacgttgaacgccaaggcggcgttgtacgcgatcgga
gagtttctggagtttagcgggttggacattcccgtgtttgtgagcggcacactggtggac
cagtcgggtcgtacactgtcgggacagacgggcgaggccttttacgtttcgatccggcac
gccaagccgatgtgtgtgggcttgaactgtgcgttgggcgccaagcacatggtacccttt
gtggagcgcttgagcaaggcggccgagtgttttgtgcacgtgtactcgaacgcgggtctg
cccaacgccatgggcgggtacgacgacacgccggaagacatggcgcgcgagaacgaggtg
tttttcgagaacggctggttgaacatggtcggagggtgctgcgggtccacgccgccgcac
atcaaggccatccgcgagacggcagagcggtaccagccccgcaagctgccggatgtgggc
cggcccaagatgtggctgtcggggctggaggacctgaaggtggaggacgtgcacaaccag
ctgggtttgccgtttctgaacgtgggcgagcggtgcaacatagccgggtcgatcaagttc
aaaaagctcatgatgaagggcgattacggcgcggccatggacattgcgaagcagcaggtg
gaggacggcgcgcacgtgatcgacatcaacgtggacgacggtatgctggatggcctagcg
gcgatgcaaaagtttgtgaagatcgcggtgacggaaccggagattgccaaggtgccgttc
atgctggacgcgtccaagtttgacattgtcatggcgggtctcaagtggtgtcagggcaag
tgcattgtgaactcgatttcgctcaaggtgggcgaggagctgtttatggagcaggccacg
ttgctgaagaagcacggcgccgcggtggttgtcatggcctttgatgagcagggtcaagcg
gccacggaagacgagaagatccgtatctgcaagcggtcgtacgacgttctggtgaacaag
gtgggtttcccaccggaggacattgtgttcgacccgaacgtactgacgattggtacgggt
atggaagagcacgcgaactacggtgtggattttatcaattctgtgaagcgcatcaaggag
gagtgtccgtacgtgaagattagtgggggtatctcgaacttgtcgtttggcttccggggt
gtgacgaagatccgggaatcgatccacgcggtgttcttgcaccacgctattaccgagtcg
ggcatggatgttggcatcgtgaactcgcacgagctactgtccgttgatgacttggaaccc
gatatgaagcttttgtgcgaaaaccttgtattcaataagactcccgatgccacagatgat
atgcttgaacgtacaaacttcgagcgatccaaaggtggagttgtggacgaggtcaaaaag
tcttcctggcgcgatcttgaaccgtccaagcgactggagcattcattggtgaacggtatt
tccgaatttgtcgattcagacgtcgaagaagctcgcgtgttggccaccaagccactagat
gtaattgagggacccttaatggacggcatgaacgttgtcggggacttgtttggagcggga
aagatgtttctaccacaagtcatcaagtctgcacgggtcatgaaaaaggcagtcgcctat
ctgttaccgtttatggatgcagagaagagggaaaatatgattgcggctggcttggatcca
gatgacgttgatcctgatgacgactcgaattacgctggcaaagtgctgatggccacagtc
aagggagatgttcatgacattggaaagaatatcgtcgctgttgtccttggatgcaacaac
tataaagtttacgacattggtgtaatgtgctcgtgtgaaaaaattctcgccaaggctaaa
gaatacaatgtcgatgtgattggtctctctggattaattactccttccttggacgagatg
gttgatgttgccaaagaaatgtccaagcaaggtttcaagcaacccttgctgattggtggc
gccactacttccaagatgcacacatccgtgaagattgctccgagctacacaacccccgag
cacccaacaattcatgttctggatgcgtctcgttccgtaacggtggtcaactctcttttg
ggagagaacaagggagagtttgtggaggatattatggaggagtacgaagaaatgcgtgaa
gattactatgcagggctcgaggaccgcaactttttaacttttgagaaggccaaggagcaa
aagattacgatcaactttgatcaatcaccggttgcagacactccaaacaaaatcggcata
accgtcattgatacggtcaagatttcggcggttgttccttacattgattggaatccattc
tttcagacgtgggagctgcgtggtcgatacccgaatcgaggctatcccaagatttttaac
gacgaagcggtcggaggcgaagccaagaaacttttccatgatgcgcagacgatgctgaat
caaatctgcgaggacggctccatgacgttgaagggagttgtcggtatcttcccggcgaac
cgtagtgaggatggcgaggatgtgcacgtttatgagacggaagccgatcgcgaatcagga
aatgtgtcgactacgttctgtatgttgcgccagcaagccgagaaggagtccgacgacccg
tatttgtcccaagccgactttgtcgcccccgcgggttacaaggatcacttgggtatgttt
gctgtttcttgttttggttgtgacgctctagtgaagaagttcgaatccgagaacgacgac
tattccaagattatggcacaagctttggcggatcgtttcgtcgaggcgtttgccgagtac
gtgcaccgcgagatgcgtctggatctctggggatacgcggctggcgaacaattgaacgag
tccgatttgctcaaggtgaaatacgacggtattcgccccgctccgggttacccgtcgcag
ccggaccatacggaaaaacgcacaatgtggaatctcctgcaggcgcaggaactggccggc
attgaattgtcggaatcgctgagcatgatgccggcgtcgtccgtttcggcgttggtcttt
gcgcaccccgagtccgagtactttgccgtgggccaagtgggtaaagatcaggtaacgaat
tacgcgtcacgcaaacagatggatttggcactctgcgaacgatggctgtctcctattctt
aattacgaacgagattaa

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