Pan troglodytes (chimpanzee): 107966703
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Entry
107966703 CDS
T01005
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00760
Nicotinate and nicotinamide metabolism
ptr01100
Metabolic pathways
ptr04068
FoxO signaling pathway
ptr04148
Efferocytosis
ptr04152
AMPK signaling pathway
ptr04211
Longevity regulating pathway
ptr04213
Longevity regulating pathway - multiple species
ptr04218
Cellular senescence
ptr04310
Wnt signaling pathway
ptr04922
Glucagon signaling pathway
ptr04936
Alcoholic liver disease
ptr05031
Amphetamine addiction
ptr05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
107966703 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
107966703 (SIRT1)
04068 FoxO signaling pathway
107966703 (SIRT1)
04152 AMPK signaling pathway
107966703 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
107966703 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
107966703 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
107966703 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
107966703 (SIRT1)
04213 Longevity regulating pathway - multiple species
107966703 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
107966703 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
107966703 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
107966703 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ptr03036
]
107966703 (SIRT1)
03029 Mitochondrial biogenesis [BR:
ptr03029
]
107966703 (SIRT1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
107966703 (SIRT1)
Chromosome and associated proteins [BR:
ptr03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
107966703 (SIRT1)
Mitochondrial biogenesis [BR:
ptr03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
107966703 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
107966703
NCBI-ProteinID:
XP_003312628
Ensembl:
ENSPTRG00000002548
ENSPTRG00000051532
VGNC:
12502
UniProt:
H2Q1Z0
A0A6D2Y7I3
LinkDB
All DBs
Position
8:80102786..80136843
Genome browser
AA seq
751 aa
AA seq
DB search
MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGESGGAAPEREV
PAAARGCPGAAAAALWREAEAETAATAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPL
ADNFYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDW
TPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKK
RKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAM
FDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGI
QRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGE
NLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDV
ELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSE
DSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQME
NPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISKRLDGNQYLFLPPNRYIFHGAE
VYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAG
FGTDGDDQEAINEAISVKQEVTDMNYPSNKS
NT seq
2256 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggccctcgcccttcagcccggcggctccccctcggcggcgggggcc
gacagggaggccgcgtcgtcccccgccggggagccgctccgcaagaggccgcggagagat
ggtcccggcctcgagcggagcccgggcgagtccggtggggcggccccagagcgtgaggtg
ccggcggcggccaggggctgcccgggtgcggcggcggcggcgctgtggcgggaggcggag
gcagagacggcggcgacggcggcggcggcgggcggggagcaagaggcccaggcgactgcg
gcggctggggaaggagacaatgggccgggcctgcagggcccatctcgggagccaccgctg
gccgacaacttctacgacgaagacgacgacgacgagggcgaggaggaggaagaggcggcg
gcggcggcgattgggtaccgagataaccttctgttcggtgatgaaattatcactaatggt
tttcattcctgtgaaagtgatgaggaggatagagcctcacatgcaagctctagtgactgg
actccaaggccacggataggtccatatacttttgttcagcaacatcttatgattggcaca
gatcctcgaacaattcttaaagatttattgccggaaacaatacctccacctgagttggat
gatatgacactgtggcagattgttattaatatcctttcagaaccaccaaaaaggaaaaaa
agaaaagatattaatacaattgaagatgctgtgaaattactgcaagagtgcaaaaaaatt
atagttctaactggagctggggtgtctgtttcatgtggaatacctgacttcaggtcaagg
gatggtatttatgctcgccttgctgtagacttcccagatcttccagatcctcaagcgatg
tttgatattgaatatttcagaaaagatccaagaccattcttcaagtttgcaaaggaaata
tatcctggacaattccagccatctctctgtcacaaattcatagccttgtcagataaggaa
ggaaaactacttcgcaactatacccaaaacatagacacgctggaacaggttgcgggaatc
caaaggataattcagtgtcatggttcctttgcaacagcatcttgcctaatttgtaaatac
aaagttgactgtgaagctgtacgaggagatatttttaatcaggtagttcctcgatgtcct
aggtgcccagctgatgaaccgcttgctatcatgaaaccagagattgtgttttttggtgaa
aatttaccagaacagtttcatagagccatgaagtatgacaaagatgaagttgacctcctc
attgttattgggtcttccctcaaagtaagaccagtagcactaattccaagttccataccc
catgaagtgcctcagatattaattaatagagaacctttgcctcatctgcattttgatgta
gagcttcttggagactgtgatgtcataattaatgaattgtgtcataggttaggtggtgaa
tatgccaaactatgctgtaaccctgtaaagctttcagaaattactgaaaaacctccacga
acacagaaagaattggcttatttgtcagagttgccacccacacctcttcatgtttcagaa
gactcaagttcaccagaaagaacttcaccaccagattcttcagtgattgtcacactttta
gaccaagcagctaagagtaatgatgatttagatgtgtctgaatcaaaaggttgtatggaa
gaaaaaccacaggaagtacaaacttctaggaatgttgaaagtattgctgaacagatggaa
aatccggatttgaagaatgttggttctagtactggggagaaaaatgaaagaacttcagtg
gctggaacagtgagaaaatgctggcctaatagagtggcaaaggagcagattagtaagcgg
cttgatggtaatcagtatctgtttttgccaccaaatcgttacattttccatggcgctgag
gtatattcagactctgaagatgacgtcttatcctctagttcttgtggcagtaacagtgat
agtgggacatgccagagtccaagtttagaagaacccatggaggatgaaagtgaaattgaa
gaattctacaatggcttagaagatgagcctgatgttccagaaagagctggaggagctgga
tttgggactgatggagatgatcaagaggcaattaatgaagctatatctgtgaaacaggaa
gtaacagacatgaactatccatcaaacaaatcatag
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