Pan troglodytes (chimpanzee): 107970128
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Entry
107970128 CDS
T01005
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X2
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00230
Purine metabolism
ptr00670
One carbon pool by folate
ptr01100
Metabolic pathways
ptr01523
Antifolate resistance
Module
ptr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107970128 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
107970128 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
107970128 (GART)
Enzymes [BR:
ptr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
107970128 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
107970128 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
107970128 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
Sacchrp_dh_NADP
CPSase_L_D2
RimK
Motif
Other DBs
NCBI-GeneID:
107970128
NCBI-ProteinID:
XP_016802637
Ensembl:
ENSPTRG00000013871
ENSPTRG00000044236
LinkDB
All DBs
Position
22:complement(34213406..34251616)
Genome browser
AA seq
987 aa
AA seq
DB search
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQ
FCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQCLCF
TDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQ
QEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCT
SLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHG
GRVLAVTAIRENLVSALEEAKKGLAAIKFEGAIYRKDIGFRAIAFLQQPRSLTYKESGVD
IAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIA
QLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAG
CALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNG
FSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITG
GGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSK
EQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSF
GKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVI
NHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFK
GSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLVEHKI
FPAALQLVASGTVQLGENGKICWVKEE
NT seq
2964 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttataattggcagtggaggaagggaacatacgctggcctggaaa
cttgcgcagtctcatcatgtcaaacaagtgttggttgccccaggaaacgcaggcactgcc
tgctctgaaaagatttcaaataccgccatctcaatcagtgaccacactgcccttgctcaa
ttctgcaaagagaagaaaattgaatttgtagttgttggaccagaagcacctctggctgct
gggattgttgggaacctgaggtctgcaggagtgcgatgctttggcccaacagcagaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacagacatggaatccca
actgcacaatggaaggctttcaccaaacctgaagaagcctgcagcttcattttgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcagtgtctgtgtttc
actgatggcaagactgtggcccccatgcccccagcacaggaccataagcgattactggag
ggagatggtggccctaacacagggggaatgggagcctattgtccagcccctcaggtttct
aatgatctattactaaaaattaaagatactgttcttcagaggacagtggatggcatgcag
caagagggtactccatatacaggtattctctatgctggaataatgctgaccaaggatggc
ccaaaagttctagagtttaattgccgttttggtgatccagagtgccaagtaatcctccca
cttcttaaaagtgatctttatgaagtgattcagtccaccttagatggactgctctgcaca
tctctgcctgtttggctagaaaaccacaccgccctaactgttgtcatggcaagtaaaggt
tatcctggagactacaccaagggtgtagagataacagggtttcctgaggctcaagctcta
ggactggaggtgttccatgcaggcactgccctcaaaaatggcaaagtagtaactcatggg
ggtagagttcttgcagtcacagccatccgggaaaatctcgtatcagccctcgaggaagcc
aagaaaggactagctgctataaagtttgagggagcaatttataggaaagacatcggcttt
cgtgccatagctttcctccagcagcccaggagtttgacttacaaggaatctggagtagat
atcgcagctggaaatatgctggtcaagaaaattcagcctttagcaaaagccacttccaga
tcaggctgtaaagttgatcttggaggttttgctggtctttttgatttaaaagcagctggt
ttcaaagatccccttctggcctctggaacagatggcgttggaactaaactaaagattgcc
cagctatgcaataaacatgataccattggtcaagatttggtagcaatgtgtgttaatgat
attctggcacaaggagcagagcccctcttcttccttgattacttttcctgtggaaaactt
gacctcagtgtaactgaagctgttgttgctggaattgctaaagcttgtggaaaagctgga
tgtgctctccttggaggtgaaacagcagaaatgcctgacatgtatccccctggagagtat
gacctagctgggtttgccgttggtgccatggagcgagatcagaaactccctcacctggaa
agaatcactgagggtgatgttgttgttggaatagcttcatctggtcttcatagcaatgga
tttagccttgtgaggaaaatcgtggcaaaatcttccctccagtactcctctccagcacct
gatggttgtggtgaccagactttaggggacttacttctcacgcctaccagaatctatagc
cattcactgttacctgtcctacgttcaggacatgtcaaagcctttgcccatattactggt
ggaggattactagagaacatccccagagtcctccctgagaaacttggggtagatttagat
gcccagacctggaggatccccagggtcttctcatggttacagcaggaaggacacctctct
gaggaagagatggccagaacatttaactgtggggttggcgctgtccttgtggtatcaaag
gagcagacagagcagattctgagggatatccagcagcacaaggaagaagcctgggtgatt
ggcagtgtggttgcacgagctgaaggttccccacgtgtgaaagtcaagaatctgattgaa
agcatgcaaataaatgggtcagtgttgaagaatggctccctgacaaatcatttctctttt
ggaaaaaaaaaggccagagtggctgtcttaatatctggaacaggatcgaacctgcaagca
cttatagacagtactcgggaaccaaatagctctgcacaaattgatattgttatctccaac
aaagccgcagtggctgggttagataaagcggaaagagctggtattcccactagagtaatt
aatcataaactgtataaaaatcgtgtagaatttgacagtgcaattgacctagtccttgaa
gagttctccatagacatagtctgtcttgcaggattcatgagaattctttctggccccttt
gtccaaaagtggaatggaaaaatgctcaatatccacccatccttgctcccttcttttaag
ggttcgaatgcccatgagcaagccctggaaaccggagtcacagttactgggtgcactgta
cactttgtagctgaagatgtggatgctggacaaattattttgcaagaagctgttcccgtg
aagaggggtgatactgtcgcaactctttctgaaagagtaaaattagtagaacataaaata
tttcctgcagcccttcagctggtggccagtggaactgtacagcttggagaaaatggcaag
atctgttgggttaaagaggaatga
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