KEGG   Pan troglodytes (chimpanzee): 450720
Entry
450720            CDS       T01005                                 
Symbol
GSTO2
Name
(RefSeq) glutathione S-transferase omega-2 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00480  Glutathione metabolism
ptr00980  Metabolism of xenobiotics by cytochrome P450
ptr00982  Drug metabolism - cytochrome P450
ptr00983  Drug metabolism - other enzymes
ptr01100  Metabolic pathways
ptr01524  Platinum drug resistance
ptr05200  Pathways in cancer
ptr05204  Chemical carcinogenesis - DNA adducts
ptr05207  Chemical carcinogenesis - receptor activation
ptr05208  Chemical carcinogenesis - reactive oxygen species
ptr05225  Hepatocellular carcinoma
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    450720 (GSTO2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    450720 (GSTO2)
   00982 Drug metabolism - cytochrome P450
    450720 (GSTO2)
   00983 Drug metabolism - other enzymes
    450720 (GSTO2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    450720 (GSTO2)
   05204 Chemical carcinogenesis - DNA adducts
    450720 (GSTO2)
   05207 Chemical carcinogenesis - receptor activation
    450720 (GSTO2)
   05208 Chemical carcinogenesis - reactive oxygen species
    450720 (GSTO2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    450720 (GSTO2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    450720 (GSTO2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    450720 (GSTO2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptr02000]
    450720 (GSTO2)
Enzymes [BR:ptr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     450720 (GSTO2)
Transporters [BR:ptr02000]
 Other transporters
  Pores ion channels [TC:1]
   450720 (GSTO2)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_N Glutaredoxin GST_C_2 GST_C_3 CLIC-like_N GST_C
Other DBs
NCBI-GeneID: 450720
NCBI-ProteinID: XP_001138494
Ensembl: ENSPTRG00000002926
VGNC: 12341
UniProt: A0A2I3TA14 A0A6D2X5Z2
LinkDB
Position
8:116383559..116413784
AA seq 243 aa
MSEDATRTLGKGSQPPGPVPEGLIRIYSMRFCPFSHRTRLVLKAKNIRHEVVNINLRNKP
EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF
CKVPHLTKECLVALRCGRECTDLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP
WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF
GLC
NT seq 732 nt   +upstreamnt  +downstreamnt
atgtctgaggatgcgaccaggaccctggggaaaggaagccagcccccagggccagtcccg
gaggggctgatccgcatctacagcatgaggttctgccccttttctcacaggacccgcctc
gtcctcaaggccaaaaacatcagacatgaagtggtcaacattaacctgagaaacaagcct
gaatggtactatacaaagcacccttttggccacattcctgtcctggagaccagccaatgc
caactgatctatgaatctgttattgcttgtgagtacctggatgacgcttatccaggaagg
aagctgtttccatatgacccttatgaacgagctcgccaaaagatgttattggagctattt
tgtaaggtcccacatttgaccaaggagtgcctggtagcgttgagatgtgggagagaatgc
actgatctgaaggcagccctgcgtcaggaattcagcaacctggaagagattcttgagtat
cagaacaccaccttctttggtggaacctgtatatccatgattgattacctcctctggccc
tggtttgagcggctggatgtgtatgggatactggactgtgtgagccacacgccagccctg
cggctctggatatcagccatgaagtgggaccccacagtctgtgctcttctcatggataag
agcattttccagggcttcttgaatctctattttcagaacaaccctaatgcctttgacttt
gggctgtgctga

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