KEGG   Pan troglodytes (chimpanzee): 450898
Entry
450898            CDS       T01005                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X4
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04010  MAPK signaling pathway
ptr04020  Calcium signaling pathway
ptr04022  cGMP-PKG signaling pathway
ptr04114  Oocyte meiosis
ptr04218  Cellular senescence
ptr04310  Wnt signaling pathway
ptr04360  Axon guidance
ptr04370  VEGF signaling pathway
ptr04380  Osteoclast differentiation
ptr04625  C-type lectin receptor signaling pathway
ptr04650  Natural killer cell mediated cytotoxicity
ptr04658  Th1 and Th2 cell differentiation
ptr04659  Th17 cell differentiation
ptr04660  T cell receptor signaling pathway
ptr04662  B cell receptor signaling pathway
ptr04720  Long-term potentiation
ptr04724  Glutamatergic synapse
ptr04728  Dopaminergic synapse
ptr04921  Oxytocin signaling pathway
ptr04922  Glucagon signaling pathway
ptr04924  Renin secretion
ptr05010  Alzheimer disease
ptr05014  Amyotrophic lateral sclerosis
ptr05020  Prion disease
ptr05022  Pathways of neurodegeneration - multiple diseases
ptr05031  Amphetamine addiction
ptr05152  Tuberculosis
ptr05163  Human cytomegalovirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05167  Kaposi sarcoma-associated herpesvirus infection
ptr05170  Human immunodeficiency virus 1 infection
ptr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    450898 (PPP3CB)
   04310 Wnt signaling pathway
    450898 (PPP3CB)
   04370 VEGF signaling pathway
    450898 (PPP3CB)
   04020 Calcium signaling pathway
    450898 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    450898 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    450898 (PPP3CB)
   04218 Cellular senescence
    450898 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    450898 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    450898 (PPP3CB)
   04660 T cell receptor signaling pathway
    450898 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    450898 (PPP3CB)
   04659 Th17 cell differentiation
    450898 (PPP3CB)
   04662 B cell receptor signaling pathway
    450898 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    450898 (PPP3CB)
   04921 Oxytocin signaling pathway
    450898 (PPP3CB)
   04924 Renin secretion
    450898 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    450898 (PPP3CB)
   04728 Dopaminergic synapse
    450898 (PPP3CB)
   04720 Long-term potentiation
    450898 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    450898 (PPP3CB)
   04380 Osteoclast differentiation
    450898 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    450898 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    450898 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    450898 (PPP3CB)
   05163 Human cytomegalovirus infection
    450898 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    450898 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    450898 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    450898 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    450898 (PPP3CB)
   05020 Prion disease
    450898 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    450898 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    450898 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    450898 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ptr01009]
    450898 (PPP3CB)
Enzymes [BR:ptr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     450898 (PPP3CB)
Protein phosphatases and associated proteins [BR:ptr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     450898 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 450898
NCBI-ProteinID: XP_001142940
Ensembl: ENSPTRG00000002631
VGNC: 7858
UniProt: K7CSU4
LinkDB
Position
8:complement(85680735..85739804)
AA seq 524 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDGSAAARKEIIRNKIRAIGKMARVFS
VLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFE
EAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHTAQ
NT seq 1575 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgtccctttccccccaacacatcgcttgacatct
gaagaagtatttgatttggatgggatacccagggttgatgttctgaagaaccacttggtg
aaagaaggtcgagtagatgaagaaattgcgcttagaattatcaatgagggtgctgccatc
cttcggagagagaaaaccatgatagaagtagaagctccaatcacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggcgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggttctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaagtattcg
gaaagagtctatgaagcttgcatggaagcttttgatagtttgcctcttgctgcactttta
aaccaacagtttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgtta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcctaattttatggatgtcttcacg
tggtctttaccgtttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactaatgactgaaggtgaagaccagtttgatggttcagctgcagcc
cggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagagtcttctct
gttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacagggatg
ttgcctagtggagtgttagctggaggacggcagaccctgcaaagtgccacagttgaggct
attgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagttttgaa
gaggcaaagggtttggataggatcaatgagagaatgccacctcggaaagatgctgtacag
caagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggacgggcaac
catactgcccagtga

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