| Entry |
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| Symbol |
LRP5
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| Name |
(RefSeq) low-density lipoprotein receptor-related protein 5 isoform X1
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| KO |
| K03068 | low density lipoprotein receptor-related protein 5/6 |
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| Organism |
ptr Pan troglodytes (chimpanzee)
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| Pathway |
| ptr04928 | Parathyroid hormone synthesis, secretion and action |
| ptr05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:ptr00001]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
451380 (LRP5)
04150 mTOR signaling pathway
451380 (LRP5)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
451380 (LRP5)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
451380 (LRP5)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
451380 (LRP5)
05226 Gastric cancer
451380 (LRP5)
05224 Breast cancer
451380 (LRP5)
09164 Neurodegenerative disease
05010 Alzheimer disease
451380 (LRP5)
05022 Pathways of neurodegeneration - multiple diseases
451380 (LRP5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:ptr04131]
451380 (LRP5)
Membrane trafficking [BR:ptr04131]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
451380 (LRP5)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
9:70356251..70493914
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| AA seq |
1614 aa
MEAAPPGPPWPLLLLLLLLALCGCPAPAAASPLLLFANRRDVRLVDAGGVKLESTIVVSG
LEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKK
LYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDPAHGYMYWTDWGETPRIERAGM
DGSTRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPF
ALTLSGDTLYWTDWQTRSIHACNKRTGGKRKEILSALYSPMDIQVLSQERQPFFHTRCEE
DNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGRTCKAGAEEVLLLARRTDLRRISLDTPD
FTDIVLQVDDIRHAIAIDYDPLEGYVYWTDDEVRAIRRAYLDGSGAQTLVNTEINDPDGI
AVDWVARNLYWTDTGTDRIEVTRLNGTSRKILVSEDLDEPRAIALHPVMGLMYWTDWGEN
PKIECANLDGQERRVLVNASLGWPNGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLL
EDKLPHIFGFTLLGDFIYWTDWQRRSIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVVG
TNPCADRNGGCSHLCFFTPHATRCGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLE
TNNNDVAIPLTGVKEASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPE
GMAVDWMGKNLYWADTGTNRIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWG
GKPRIVRAFMDGTNCMTLVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVI
ADDLPHPFGLTQYSDYIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQD
GLNDCMHNNGQCGQLCLAIPGGHRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIP
DDQHSPDLILPLHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGTQPFVLTSLSQGQN
PDRQPHDLSIDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVNAERGYL
YFTNMQDRAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDL
SGANRLTLEDANIVQPLGLTVLGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGI
HAVEEVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSP
DQFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGEA
DCQDRSDEADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSDDSP
AHSSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLNFIAPG
GSQHGPFTGIACGKSMMSSVSLMGGRGGVPLYDRNHVTGASSSSSSSTKATLYPPILNPP
PSPATDPSLYNMDMFYSSNIPATARPYRPYIIRGMAPPTTPCSTDVCDSDYSASRWKASK
YYLDLNSDSDPYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPPPPSPCTDSS |
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| NT seq |
4845 nt +upstreamnt +downstreamnt
atggaggcagcgccgcccgggccgccgtggccgctgctgctgctgctgctgctgctggcg
ctgtgcggctgcccggcccccgccgcggcctcgccgctcctgctatttgccaaccgccgg
gacgtacggctggtggacgccggcggagtcaagctggagtccaccatcgtggtcagcggc
ctggaggatgcggccgcagtggacttccagttttccaagggagccgtgtactggacagac
gtgagcgaggaggccatcaagcagacctacctgaaccagacgggggccgccgtgcagaac
gtggtcatctccggcctggtctctcccgacggcctcgcctgcgactgggtgggcaagaag
ctgtactggacggactcagagaccaaccgcatcgaggtggccaacctcaatggcacatcc
cggaaggtgctcttctggcaggaccttgaccagccgagggccatcgccttggaccccgct
cacgggtacatgtactggacagactggggtgagacgccccggattgagcgggcagggatg
gatggcagcacccggaagatcattgtggactcggacatttactggcccaatggactgacc
atcgacctggaggagcagaagctctactgggctgacgccaagctcagcttcatccaccgt
gccaacctggatggctcgttccggcagaaggtggtggagggcagcctgacgcaccccttc
gccctgacgctctccggggacactctgtactggacagactggcagacccgctccatccat
gcctgcaacaagcgcactggggggaagaggaaggagatcctgagtgccctctactcaccc
atggacatccaggtgctgagccaggagcggcagcctttcttccatactcgctgtgaggag
gacaatggcggctgctcccacctgtgcctgctgtccccaagcgagcctttctacacatgc
gcctgccccacgggtgtgcagctgcaggacaacggcaggacgtgtaaggcaggagccgag
gaagtgctgctgctggcccggcggacggacctacggaggatctcgctggacacgccggac
ttcaccgacatcgtgctgcaggtggacgacatccggcacgccattgccatcgactacgac
ccgctagagggctatgtctactggacagatgacgaggtgcgggccatccgcagggcgtac
ctggacgggtctggggcgcagacgctggtcaacaccgagatcaacgaccccgatggcatc
gcggtcgactgggtggcccgaaacctctactggaccgacacgggcacggaccgcatcgag
gtgacgcgcctcaacggcacctcccgcaagatcctggtgtcggaggacctggacgagccc
cgagccatcgcactgcaccccgtgatgggcctcatgtactggacagactggggagagaac
cctaaaatcgagtgtgccaacttggacgggcaggagcggcgtgtgctggtcaatgcctcc
ctcgggtggcccaacggcctggccctggacctgcaggaggggaagctgtactggggagac
gccaagacagacaagatcgaggtgatcaatgttgatgggacgaagaggcggaccctcctg
gaggacaagctcccgcacattttcgggttcacgctgctgggggacttcatctactggact
gactggcagcgccgcagcatcgagcgggtgcacaaggtcaaggccagccgggacgtcatc
attgaccagctgcctgacctgatggggctcaaagctgtgaatgtggccaaggtcgttgga
accaacccgtgtgcggacaggaacggggggtgcagccacctgtgcttcttcacaccccac
gcaacccggtgtggctgccccatcggcctggagctgctgagtgacatgaagacctgcatc
gtgcctgaggccttcttggtcttcaccagcagagccgccatccacaggatctccctcgag
accaataacaatgacgtggccatcccgcttacgggcgtcaaggaggcctcagccctggac
tttgatgtgtccaacaaccacatctactggacagacgtcagcctgaagaccatcagccgc
gccttcatgaacgggagctcggtggagcacgtggtggagtttggccttgactaccccgag
ggcatggccgttgactggatgggcaagaacctctactgggccgacactgggaccaacaga
atcgaagtggcgcggctggacgggcagttccggcaagtcctcgtgtggagggacttggac
aacccgaggtcgctggccctggatcccaccaagggctacatctactggaccgagtggggc
ggcaagccgaggatcgtgcgggccttcatggacgggaccaactgcatgacgctggtggac
aaggtgggccgggccaacgacctcaccattgactacgctgaccagcgcctctactggacc
gacctggacaccaacatgatcgagtcgtccaacatgctgggtcaggagcgggtcgtgatt
gccgacgatctcccgcacccgttcggtctgacgcagtacagcgattatatctactggaca
gactggaatctgcacagcattgagcgggccgacaagactagcggccggaaccgcaccctc
atccagggccacctggacttcgtgatggacatcctggtgttccactcctcccgccaggat
ggcctcaatgactgtatgcacaacaacgggcagtgtgggcagctgtgccttgccatcccc
ggcggccaccgctgcggctgcgcctcacactacaccctggaccccagcagccgcaactgc
agcccgcccaccaccttcttgctgttcagccagaaatctgccatcagtcggatgatcccg
gacgaccagcacagcccggatctcatcctgcccctgcatggactgaggaacgtcaaagcc
atcgactatgacccactggacaagttcatctactgggtggatgggcgccagaacatcaag
cgagccaaggacgacgggacccagccctttgttttgacctctctgagccaaggccaaaac
ccagacaggcagccccacgacctcagcatcgacatctacagccggacactgttctggacg
tgtgaggccacgaataccatcaacgtccacaggctgagcggggaagccatgggggtggtg
ctgcgtggggaccgcgacaaacccagggccatcgtcgtcaacgcggagcgagggtacctg
tacttcaccaacatgcaggaccgggcagccaagatcgaacgcgcagccctggacggcacc
gagcgcgaggtcctcttcaccaccggcctcatccgccctgtggccctggtggtggacaac
acactgggcaagctgttctgggtggatgcggacctgaagcgcattgagagctgtgacctg
tcaggggccaaccgcctgaccctggaggacgccaacatcgtgcagcctctgggcctgacc
gttcttggcaagcatctctactggatcgaccgccagcagcagatgatcgagcgtgtggag
aagaccaccggggacaagcggactcgcatccagggccgtgtcgcccacctcactggcatc
catgcggtggaggaagtcagcctggaggagttctcagcccacccatgtgcccgtgacaat
ggtggctgctcccacatctgtattgccaagggtgatgggacaccacggtgctcatgccca
gtccacctcgtgctcctgcagaacctgctgacctgtggagagccgcccacctgctccccg
gaccagtttgcatgtgccacaggggagatcgactgtatccccggggcctggcgctgtgac
ggctttcccgagtgcgacgaccagagcgatgaggagggctgccccgtgtgctccgccgcc
cagttcccctgcgcgcggggccagtgtgtggacctgcgcctgcgctgcgacggcgaggca
gactgtcaggaccgctcagacgaggcggactgtgacgccatctgcctgcccaaccagttc
cggtgtgcgagcggccagtgtgtcctcatcaaacagcagtgcgactccttccccgactgt
atcgacggctccgacgagctcatgtgtgaaatcaccaagccgccctcagacgacagcccg
gcccacagcagtgccatcgggcccgtcattggcatcattctctctctcttcgtcatgggt
ggtgtctattttgtgtgccagcgcgtggtgtgccagcgctatgcgggggccaacgggccc
ttcccgcacgagtatgtcagcgggaccccgcacgtgcccctcaatttcatagccccgggc
ggttcccagcatggccccttcacaggcatcgcatgcggaaagtccatgatgagctccgtg
agcctgatggggggccggggcggggtgcccctctacgaccggaaccacgtcacaggggcc
tcgtccagcagctcgtccagcacgaaggccacgctgtacccgccgatcctgaacccgccg
ccctccccggccacggacccctccctgtacaacatggacatgttctactcttcaaacatt
ccggccactgcgagaccgtacaggccctacatcattcgaggaatggcgcccccgacgacg
ccctgcagcaccgacgtgtgtgacagcgactacagcgccagccgctggaaggccagcaag
tactacctggatttgaactcggactcagacccctacccacccccacccacgccccacagc
cagtacctgtcggcggaggacagctgcccgccctcgcctgccaccgagaggagctacttc
catctcttcccgccccctccgtccccctgcacggactcatcctga |
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