Pan troglodytes (chimpanzee): 451866 Help Entry 451866            CDS       T01005                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr00230   Purine metabolism ptr01100   Metabolic pathways ptr01522   Endocrine resistance ptr04015   Rap1 signaling pathway ptr04022   cGMP-PKG signaling pathway ptr04024   cAMP signaling pathway ptr04062   Chemokine signaling pathway ptr04072   Phospholipase D signaling pathway ptr04081   Hormone signaling ptr04082   Neuroactive ligand signaling ptr04114   Oocyte meiosis ptr04211   Longevity regulating pathway ptr04213   Longevity regulating pathway - multiple species ptr04261   Adrenergic signaling in cardiomyocytes ptr04270   Vascular smooth muscle contraction ptr04371   Apelin signaling pathway ptr04540   Gap junction ptr04611   Platelet activation ptr04713   Circadian entrainment ptr04714   Thermogenesis ptr04723   Retrograde endocannabinoid signaling ptr04724   Glutamatergic synapse ptr04725   Cholinergic synapse ptr04727   GABAergic synapse ptr04742   Taste transduction ptr04750   Inflammatory mediator regulation of TRP channels ptr04911   Insulin secretion ptr04912   GnRH signaling pathway ptr04913   Ovarian steroidogenesis ptr04914   Progesterone-mediated oocyte maturation ptr04915   Estrogen signaling pathway ptr04916   Melanogenesis ptr04918   Thyroid hormone synthesis ptr04921   Oxytocin signaling pathway ptr04923   Regulation of lipolysis in adipocytes ptr04924   Renin secretion ptr04925   Aldosterone synthesis and secretion ptr04926   Relaxin signaling pathway ptr04927   Cortisol synthesis and secretion ptr04928   Parathyroid hormone synthesis, secretion and action ptr04934   Cushing syndrome ptr04935   Growth hormone synthesis, secretion and action ptr04961   Endocrine and other factor-regulated calcium reabsorption ptr04962   Vasopressin-regulated water reabsorption ptr04970   Salivary secretion ptr04971   Gastric acid secretion ptr04972   Pancreatic secretion ptr04976   Bile secretion ptr05032   Morphine addiction ptr05163   Human cytomegalovirus infection ptr05166   Human T-cell leukemia virus 1 infection ptr05200   Pathways in cancer ptr05207   Chemical carcinogenesis - receptor activation ptr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ptr00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     451866 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     451866 (ADCY6)    04371 Apelin signaling pathway     451866 (ADCY6)    04072 Phospholipase D signaling pathway     451866 (ADCY6)    04024 cAMP signaling pathway     451866 (ADCY6)    04022 cGMP-PKG signaling pathway     451866 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     451866 (ADCY6)    04081 Hormone signaling     451866 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     451866 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     451866 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     451866 (ADCY6)    04062 Chemokine signaling pathway     451866 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     451866 (ADCY6)    04923 Regulation of lipolysis in adipocytes     451866 (ADCY6)    04912 GnRH signaling pathway     451866 (ADCY6)    04913 Ovarian steroidogenesis     451866 (ADCY6)    04915 Estrogen signaling pathway     451866 (ADCY6)    04914 Progesterone-mediated oocyte maturation     451866 (ADCY6)    04921 Oxytocin signaling pathway     451866 (ADCY6)    04926 Relaxin signaling pathway     451866 (ADCY6)    04935 Growth hormone synthesis, secretion and action     451866 (ADCY6)    04918 Thyroid hormone synthesis     451866 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     451866 (ADCY6)    04916 Melanogenesis     451866 (ADCY6)    04924 Renin secretion     451866 (ADCY6)    04925 Aldosterone synthesis and secretion     451866 (ADCY6)    04927 Cortisol synthesis and secretion     451866 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     451866 (ADCY6)    04270 Vascular smooth muscle contraction     451866 (ADCY6)   09154 Digestive system    04970 Salivary secretion     451866 (ADCY6)    04971 Gastric acid secretion     451866 (ADCY6)    04972 Pancreatic secretion     451866 (ADCY6)    04976 Bile secretion     451866 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     451866 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     451866 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     451866 (ADCY6)    04727 GABAergic synapse     451866 (ADCY6)    04725 Cholinergic synapse     451866 (ADCY6)    04723 Retrograde endocannabinoid signaling     451866 (ADCY6)   09157 Sensory system    04742 Taste transduction     451866 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     451866 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     451866 (ADCY6)    04213 Longevity regulating pathway - multiple species     451866 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     451866 (ADCY6)    04714 Thermogenesis     451866 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     451866 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     451866 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     451866 (ADCY6)    05163 Human cytomegalovirus infection     451866 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     451866 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     451866 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     451866 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     451866 (ADCY6) Enzymes [BR:ptr01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      451866 (ADCY6) SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom HNOBA GBR2_CC TBK1_ULD Motif Other DBs NCBI-GeneID:  451866 NCBI-ProteinID:  XP_016779005 Ensembl:  ENSPTRG00000004885 VGNC:  12756 UniProt:  K7DS66 A0A6D2X1T8 LinkDB All DBs Position 10:47077573..47100460 Genome browser AA seq 1168 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGP PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGRSCWR RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTVVLLAFHAAPARPHPAY VALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLW CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKK YSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLIAVLICAVYSC GSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLT PADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLA MIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG YQLECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3507 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggcctcctggtccctaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgttcgcggcgccgtggcactcgggcaggtggcttctgcacg ccccgctatatgagctgcctccgggatgcagagccacccagccccacccctgcgggcccc cctcggtgcccctggcaggatgacgccttcatccggaggggcggcccaggcaagggcaag gagctggggctgcgggcagtggccctgggcttcgaggataccgaggtgacaacgacagcg ggcgggacggctgaggtggcgcccgacgcggtgcccaggagtgggcgatcctgctggcgc cgtctggtgcaggtgttccagtcgaagcagttccgttcggccaagctggagcgcctgtac cagcggtacttcttccagatgaaccagagcagcctgacgctgctgatggcggtgctggtg ctgctcacagtggtgctgctggctttccacgccgcacccgcccgccctcaccctgcctat gtggcactgttggcctgtgccgccgccctgttcgtggggctcatggtggtgtgtaaccgg catagcttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcg gcagtgcaggtcgggggcgctctcgcagcagacccgcgcagcccctctgcgggcctctgg tgccctgtgttctttgtctacatcgcctacacgctcctccccatccgcatgcgggctgcc gtcctcagcggcctgggcctctccaccttgcatttgatcttggcctggcaacttaaccgt ggtgatgccttcctctggaagcagctcggtgccaatgtgctgctgttcctctgcaccaac gtcattggcatctgcacacactatccagcagaggtgtctcagcgccaggcctttcaggag acccgcggttacatccaggcccggctccacctgcagcatgagaatcggcagcaggagcgg ctgctgctgtcggtattgccccagcacgttgccatggagatgaaagaagacatcaacaca aaaaaagaagacatgatgttccacaagatctacatacagaagcatgacaatgtcagcatc ctgtttgcagacattgagggcttcaccagcctggcatcccagtgcaccgcgcaggagctg gtcatgaccctgaatgagctctttgcccggtttgacaagctggctgcggagaatcactgc ctgaggatcaagatcttgggggactgttactactgtgtgtcagggctgccggaggcccgg gccgaccatgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctg gtacgtgaggtgacaggtgtgaatgtgaacatgcgcgtgggcatccacagcgggcgcgtg cactgcggcgtccttggcttgcggaaatggcagttcgatgtgtggtccaatgatgtgacc ctggccaaccacatggaggcaggaggccgggctggccgcatccacatcactcgggcaaca ctgcagtacctgaacggggactacgaggtggagccaggccgtggtggcgagcgcaacgcg tacctcaaggagcagcacattgagactttcctcatcctgggcgccagccagaaacggaaa gaggagaaggccatgctggccaagctgcagcggactcgggccaactccatggaagggctg atgccgcgctgggtgcctgatcgtgccttctcccggaccaaggactccaaggccttccgc cagatgggcattgatgattccagcaaagacaaccggggcacccaagatgccctgaaccct gaggatgaggtggatgagttcctgagccgtgccatcgatgcccgcagcattgatcagctg cggaaggaccatgtgcgccggtttctgctcaccttccagagagaggatcttgagaagaag tactcccggaaggtggatccccgcttcggagcctacgttgcctgtgccctgttggtcttc tgcttcatctgcttcatccagcttctcatcttcccacactccaccctgatgcttgggatc tatgccagcatcttcctgctgctgctaatcgccgtgctgatctgtgccgtgtactcctgt ggttctctgttccctaaggccctgcaacgtctgtcccgcagcattgtccgctcacgggca catagcaccgcagttggcatcttttccgtcctgcttgtgtttacttctgccattgccaac atgttcacctgtaaccacacccccatacggacctgtgcagcccggatgctgaatttaaca cctgctgacatcactgcctgccacctgcagcagctcaattactctctgggcctggatgct cccctgtgtgagggcaccatgcccacctgcagctttcctgagtacttcatcgggaacatg ctgctgagtctcttggccagctctgtcttcctacacatcagcagcatcgggaagttggcc atgatctttgtcttggggctcatctatttggtgctgcttctgctgggtcccccagccacc atctttgacaactatgacctactgcttggcgtccatggcttggcttcttccaatgagacc tttgatgggctggactgtccagctgcagggagggtggccctcaaatatatgacccctgtg attctgctggtgtttgcgctggcgctgtatctgcatgctcagcaggtggagtcgactgcc cgcctagacttcctctggaaactacaggcaacaggggagaaggaggagatggaggagcta caggcatacaaccggaggctgctgcataacattctgcccaaggacgtggcggcccacttc ctggcccgggagcgccgcaatgatgaactctactatcagtcgtgtgagtgtgtggctgtt atgtttgcctccattgccaacttctctgagttctatgtggagctagaggcaaacaatgag ggtgtcgagtgcctgcggctgctcaacgagatcatcgctgactttgatgagattatcagc gaggagcggttccggcagctggaaaagatcaagacgattggtagcacctacatggctgcc tcagggctgaacgccagcacctacgatcaggtgggccgctcccacatcactgccctggct gactacgccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaat ttccagatgaagattgggctgaacatgggcccagtcgtggcaggtgtcatcggggctcgg aagccacagtatgacatctgggggaacacagtgaatgtctctagtcgtatggacagcacg ggggtccccgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggc taccagctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctac ttcctcaatgggggccccagcagttaa

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