Pan troglodytes (chimpanzee): 452007
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Entry
452007 CDS
T01005
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X2
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00260
Glycine, serine and threonine metabolism
ptr00630
Glyoxylate and dicarboxylate metabolism
ptr00670
One carbon pool by folate
ptr01100
Metabolic pathways
ptr01200
Carbon metabolism
ptr01230
Biosynthesis of amino acids
ptr01240
Biosynthesis of cofactors
ptr01523
Antifolate resistance
ptr04981
Folate transport and metabolism
Module
ptr_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
452007 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
452007 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
452007 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
452007 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
452007 (SHMT2)
Enzymes [BR:
ptr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
452007 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
452007
NCBI-ProteinID:
XP_009423356
Ensembl:
ENSPTRG00000005124
VGNC:
8532
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Position
10:complement(38798450..38803942)
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AA seq
506 aa
AA seq
DB search
MRSPNGLLPTACCPRPELVAGPPATSELRCCTSLCFGRLGLCRDVGSWSGWPFGLSTATQ
PRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEVVDEIELL
CQHRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMS
DVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMR
EVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKA
VDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNA
RAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSA
ITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSET
SQRLANLRQRVEQFARAFPMPGFDEH
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
atgcgttctccgaacggtcttcttccgacagcttgctgccctagaccagagttggtggct
ggacctcctgcgacttccgagttgcgatgctgtacttctctttgtttcgggcggctcggc
ctctgcagagatgtgggcagctggtcaggatggccattcgggctcagcacagcaacgcag
cccagactcagactggggaagcaaacaggggctggacaggccaggagagcctgtcggaca
gtgatcctgagatgtgggagttgctgcagagggagaaggacaggcagtgtcgtggcctgg
agctcattgcctcagagatactatgggggagcagaggtggtggatgaaattgagcttctg
tgccagcaccgggccttggaagcctttgacctggatcctgcacagtggggagtcaatgtc
cagccctactccgggtccccagccaacctggccgtctacacagcccttctgcaacctcac
gaccggatcatggggctggacctgcccgatgggggccatcttacccacggctacatgtct
gacgtcaagcggatatcagccacgtccatcttcttcgagtctatgccctataagctcaac
cccaaaactggcctcattgactatgaccagctggcactgactgctcgacttttccggcca
cggctcatcatagctggcaccagcgcctatgctcgcctcattgactacgcccgcatgaga
gaggtgtgtgatgaagtcaaagcacacctgctggcagacatggcccacatcagtggcctg
gtggctgccaaggtgattccctcgcctttcaagcacgcggacatcgtcaccaccactact
cacaagactcttcgaggggccaggtcagggctcatcttctaccggaaaggggtgaaggct
gtggaccccaagactggccgggagatcccttacacatttgaggaccgaatcaactttgcc
gtgttcccatccctacaggggggcccccacaatcatgccattgctgcagtagctgtggcc
ctaaagcaggcctgcacccccatgttccgggagtactccctgcaggttctgaagaatgct
cgggccatggcagatgccctgctagagcgaggctactcactggtatcaggtggtactgac
aaccacctggtgctggtggacctgcggcccaagggcctggatggagctcgggctgagcgg
gtgctagagcttgtatccatcactgccaacaagaacacctgtcctggagaccgaagtgcc
atcacaccgggcggcctgcggcttggggccccagccttaacttctcgacagttccgtgag
gatgacttccggagagttgtggactttatagatgaaggggtcaacattggcttagaggtg
aagagcaagactgccaagctccaggatttcaaatccttcctgcttaaggactcagaaaca
agtcagcgtctggccaacctcaggcaacgggtggagcagtttgccagggccttccccatg
cctggttttgatgagcattga
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