Pan troglodytes (chimpanzee): 453676
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Entry
453676 CDS
T01005
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01521
EGFR tyrosine kinase inhibitor resistance
ptr01522
Endocrine resistance
ptr04010
MAPK signaling pathway
ptr04014
Ras signaling pathway
ptr04015
Rap1 signaling pathway
ptr04066
HIF-1 signaling pathway
ptr04068
FoxO signaling pathway
ptr04081
Hormone signaling
ptr04114
Oocyte meiosis
ptr04140
Autophagy - animal
ptr04144
Endocytosis
ptr04150
mTOR signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr04152
AMPK signaling pathway
ptr04211
Longevity regulating pathway
ptr04213
Longevity regulating pathway - multiple species
ptr04510
Focal adhesion
ptr04520
Adherens junction
ptr04550
Signaling pathways regulating pluripotency of stem cells
ptr04730
Long-term depression
ptr04913
Ovarian steroidogenesis
ptr04914
Progesterone-mediated oocyte maturation
ptr05200
Pathways in cancer
ptr05202
Transcriptional misregulation in cancer
ptr05205
Proteoglycans in cancer
ptr05214
Glioma
ptr05215
Prostate cancer
ptr05218
Melanoma
ptr05224
Breast cancer
ptr05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
453676 (IGF1R)
04014 Ras signaling pathway
453676 (IGF1R)
04015 Rap1 signaling pathway
453676 (IGF1R)
04066 HIF-1 signaling pathway
453676 (IGF1R)
04068 FoxO signaling pathway
453676 (IGF1R)
04151 PI3K-Akt signaling pathway
453676 (IGF1R)
04152 AMPK signaling pathway
453676 (IGF1R)
04150 mTOR signaling pathway
453676 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
453676 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
453676 (IGF1R)
04140 Autophagy - animal
453676 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
453676 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
453676 (IGF1R)
04520 Adherens junction
453676 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
453676 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
453676 (IGF1R)
04914 Progesterone-mediated oocyte maturation
453676 (IGF1R)
09156 Nervous system
04730 Long-term depression
453676 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
453676 (IGF1R)
04213 Longevity regulating pathway - multiple species
453676 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
453676 (IGF1R)
05202 Transcriptional misregulation in cancer
453676 (IGF1R)
05205 Proteoglycans in cancer
453676 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
453676 (IGF1R)
05214 Glioma
453676 (IGF1R)
05218 Melanoma
453676 (IGF1R)
05215 Prostate cancer
453676 (IGF1R)
05224 Breast cancer
453676 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
453676 (IGF1R)
01522 Endocrine resistance
453676 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
453676 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ptr04090
]
453676 (IGF1R)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
453676 (IGF1R)
Protein kinases [BR:
ptr01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
453676 (IGF1R)
CD molecules [BR:
ptr04090
]
Proteins
453676 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
453676
NCBI-ProteinID:
XP_016782981
Ensembl:
ENSPTRG00000007489
VGNC:
11907
UniProt:
H2QA49
A0A6D2WGH0
LinkDB
All DBs
Position
16:90467150..90781823
Genome browser
AA seq
1364 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASLPLPDRHSGH
KAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4095 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccaggcatcgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
attaccgagtacttgctgctgttccgagtggctggcctcgagagcctcggagacctcttc
cccaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcggtgtccaataactacattgtggggaataagcccccaaaggaatgtggggac
ctgtgtccagggaccatggaggagaagccgatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcacgtgtggg
aagcgggcgtgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgtgtagcttgccgccactactactatgccggtgtctgt
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactccgaggggtttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgcccgaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaacatccgacgggggaataacattgcttcagagctggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattctcatgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tacgtcctcgacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattatgtgtttccgaaatttac
cgcatggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacg
tcgaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaagaatgtcacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctcccgcccaacaag
gacgtggagcccggcatcttactacatgggctgaagccctggactcagtacgccgtttac
gtcaaggctgtgaccctcaccatggtggagaatgaccatatccgtggggccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagca
tcgaactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaac
ctgagttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacatt
gaggaggtcacagagaaccccaagactgaggtgtgtggtggggagaaagggccttgctgc
gcctgccccaaaactgaagctgagaagcaggccgagaaggaggaggctgaataccgcaaa
gtctttgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggccgca
gacacctacaacatcaccgacccggaagagctggagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtgatttctaaccttcggcctttcacattgtaccgc
atcgatatccacagctgcaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaaggactatgcccgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaagtatggaggggccaagctaaaccggctaaacccggggaac
tacacagcccggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctg
cccgtcgctgtcctgttgatcgtgggagggttggtgattatgctgtacgtcttccataga
aagagaaataacagcaggctggggaatggagtgctgtatgcctctgtgaacccggagtac
ttcagcgctgctgatgtgtacgttcccgatgagtgggaggtggctcgggagaagatcacc
atgagccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagatgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcaagc
atgcgtgaaaggattgagtttctcaacgaagcttctgtgatgaaggagttcaattgtcac
catgtggtgcgattgctgggtgtggtgtcccaaggccagccaacactggtcatcatggaa
ctgatgacacggggcgatctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctgagcaagatgattcagatggccggagagattgca
gacggcatggcatacctcaacgccaataagttcgtccacagagaccttgctgcccggaat
tgcatggtagccgaagatttcacagtcaaaatcggagattttggtatgacgcgagatatc
tatgagacagactattaccggaaaggagggaaagggctgctgcccgtgcgctggatgtct
cccgagtccctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtc
gtcctctgggagatcgccacactggccgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccagacaactgtcccgacatg
ctgtttgaactgatgcgcatgtgctggcagtataaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaagaggagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagctgcccgagccggaggagctggacctggagccagagaacatg
gagagcgtccccctggacccctcggcctccctgccactgcccgacagacactcaggacac
aaggccgagaacggccccggccctggggtgctggtcctccgcgccagcttcgacgagaga
cagccgtacgcacacatgaacgggggccgcaagaacgagcgggccttgccgctgccccag
tcttcgacctgctga
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integrated database retrieval system
