| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
ptr Pan troglodytes (chimpanzee)
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| Pathway |
| ptr04977 | Vitamin digestion and absorption |
| ptr04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:ptr00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
453952 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
453952 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
453952 (ABCC1)
04981 Folate transport and metabolism
453952 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
453952 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
453952 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:ptr02000]
453952 (ABCC1)
Enzymes [BR:ptr01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
453952 (ABCC1)
Transporters [BR:ptr02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
453952 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
18:18418816..18606078
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| AA seq |
1540 aa
MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRH
DRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFS
LLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSD
LWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEAL
IVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPD
WQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPIN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILSGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPT
LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQND
SLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHGMSYLPQVDVIIV
MSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAENGSTVMDEEEAGVTGVSGPGK
EAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEAD
KAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEH
TKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGN
LVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQR
FYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYP
SIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMS
SEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLR
HINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKIT
IIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLS
VGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTI
MDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4623 nt +upstreamnt +downstreamnt
atggcgctccggggcttctgcagcgccgatggctccgacccgctctgggactggaatgtc
acgtggaataccagcaaccccgacttcaccaagtgctttcagaacacggtcctcgtgtgg
gtgccttgtttttacctctgggcctgtttccccttctacttcctctatctctcccgacat
gaccgaggctacattcagatgacacctctcaacaaaaccaaaactgccttgggatttttg
ctgtggatcgtctgctgggcagacctcttctactctttctgggaaagaagtcggggcata
ttcctggccccagtgtttctggtcagcccaactctcttgggcatcaccatgctgcttgct
acctttttaattcagctggagaggaggaagggagttcagtcttcagggatcatgctcact
ttctggctggtagccctagtgtgtgccctcgccatcctgagatccaaaattatgacagcc
ttaaaagaggatgcccaggtggacctgtttcgtgacatcactttctacgtctacttttcc
ctcttactcattcagctcgtcttgtcctgtttctcagatcgctcacccctgttctcggaa
accatccacgaccctaatccctgcccagagtccagcgcttccttcctgtcgaggatcacc
ttctggtggatcacagggttgattgtccggggctaccgccagcccctggagggcagtgac
ctctggtccttaaacaaggaggacacgtcggaacaagtcgtgcctgttttggtaaagaac
tggaagaaggaatgcgccaagactaggaagcagccggtgaaggtcgtgtactcctccaag
gatcctgcccagccgaaagagagttccaaggtggatgcgaatgaggaggtggaggctttg
attgtcaagtccccacagaaggagtggaacccctctctgtttaaggtgttatacaagacc
tttgggccctacttcctcatgagcttcttctttaaggccatccacgacctgatgatgttt
tccgggccgcagatcttaaagttgctcatcaagttcgtgaacgacacgaaggccccagac
tggcagggctacttctacaccgtgctgctgtttgtcactgcctgcctgcagaccctcgtg
ctgcaccagtacttccacatctgcttcgtcagtggcatgagaatcaagaccgctgtcatt
ggggctgtctatcggaaggccctggtgatcaccaattcagccagaaaatcctccacggtc
ggggaaattgtcaacctcatgtctgtggacgctcagaggttcatggacttggccacgtac
attaacatgatctggtcagcccccctgcaagtcatccttgctctctacctcctgtggctg
aacctgggcccttccgtcctggctggagtggcggtgatggtcctcatggtgcccatcaat
gctgtgatggcgatgaagaccaagacttaccaggtggcccacatgaagagcaaagacaat
cggatcaagctgatgaatgaaattctcagtgggatcaaagtgctaaagctttatgcctgg
gagctggcattcaaggacaaggtgctggccatcaggcaggaggagctgaaggtgctgaag
aagtctgcctacctgtcagccgtgggcaccttcacctgggtctgcacgcccttcctggtg
gccctgtgcacgtttgccgtctacgtgaccattgacgagaacaacatcctggatgcccag
acagccttcgtgtctttggccttgttcaacatcctccggtttcccctgaacattctcccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaaacgcctgaggatctttctc
tcccatgaggagctggaacctgacagcatcgagcgacggcctgtcaaagacggcgggggc
acgaacagcatcaccgtgaggaatgccacattcacctgggccaggagcgaccctcccaca
ctgaatggcatcaccttctccatccccgaaggtgctttggtggccgtggtgggccaggtg
ggctgcggaaagtcgtccctgctctcagccctcttggctgagatggacaaagtggagggg
cacgtggctatcaagggctccgtggcctatgtgccacagcaggcctggattcagaatgat
tctctccgagaaaacatcctttttggatgtcagctggaggaaccatattacaggtccgtg
atacaggcctgtgccctcctcccagacctggaaatcctgcccagcggggatcggacagag
attggcgagaagggcgtgaacctgtctgggggccagaagcagcgcgtgagcctggcccgg
gccgtgtactccaacgctgacatttacctcttcgatgatcccctctcagcagtggatgcc
catgtgggaaaacacatctttgaaaatgtgattggccccaaggggatgctgaagaacaag
acgcggatcttggtcacgcacggcatgagctacttgccgcaggtggacgtcatcatcgtc
atgagtggcggcaagatctctgagatgggctcctaccaggagctgctggcccgagacggc
gccttcgctgagttcctgcgtacctatgccagcacagagcaggagcaggacgcagagaac
ggcagcacagtgatggacgaggaggaagcaggggtcacaggcgtcagcggtccagggaag
gaagcaaagcaaatggagaatggcatgctggtgacggacagtgcagggaagcaactgcag
agacagctcagcagctcctcctcctatagcggggacatcagcaggcaccacaacagcacc
gcagaactgcagaaagctgaggccaagaaggaggagacctggaagctgatggaggctgac
aaggcgcagacagggcaggtcaagctttccgtgtactgggactacatgaaggccatcgga
ctcttcatctcctttctcagcatcttccttttcatgtgtaaccatgtgtccgcgctggct
tccaactattggctcagcctctggactgatgaccccatcgtcaacgggactcaggagcac
acgaaagtccggctgagcgtctatggagccctgggcatttcacaagggatcgccgtgttt
ggctactccatggccgtgtccatcggggggatcttggcttcccgctgtctgcacgtggac
ctgctgcacagcatcctgcggtcacccatgagcttctttgagcggacccccagtgggaac
ctggtgaaccgcttctccaaggagctggacacagtggactccatgatcccggaggtcatc
aagatgttcatgggctccctgttcaacgtcattggtgcctgcatcgttatcctgctggcc
acgcccatcgccgccatcatcatcccgcccctcggcctcatctacttcttcgtccagagg
ttctacgtggcttcctcccggcagctgaagcgcctcgagtcggtcagccgctccccggtc
tattcccatttcaacgagaccttgctgggggtcagcgtcattcgagccttcgaggagcag
gagcgcttcatccaccagagtgacctgaaggtggacgagaaccagaaggcctattacccc
agcatcgtggccaacaggtggctggccgtgcggctggagtgtgtgggcaactgcatcgtt
ctgtttgctgccctgtttgcggtgatctccaggcacagcctcagcgctggcttggtgggc
ctctcagtgtcttactcattgcaggtcaccacgtacttgaactggctggttcggatgtca
tctgaaatggaaaccaacatcgtggccgtggagaggctcaaggagtactcagagactgag
aaggaggcgccctggcaaatccaggagacagctccgcccagcagctggccccaggtgggc
cgagtggaattccggaactactgcctgcgctaccgagaggacctggacttcgttctcagg
cacatcaatgtcacgatcaatgggggagaaaaggtcggcatcgtggggcggacgggagct
gggaagtcgtccctgaccctgggcttatttcggatcaacgagtctgccgaaggagagatc
atcatcgatggcatcaacatcgccaagatcggcctgcacgacctccgcttcaagatcacc
atcatcccccaggaccctgttttgttttcgggttccctccgaatgaacctggacccattc
agccagtactcggatgaagaagtctggacgtccctggagctggcccacctgaaggacttc
gtgtcagcccttcctgacaagctggaccacgagtgtgcggaaggcggggagaacctcagt
gttgggcagcgccagcttgtgtgcctagcccgggccctgctgaggaagacgaagatcctt
gtgttggatgaggccacggcagccgtggacctggaaacggacgacctcatccagtccacc
atccggacacagttcgaggactgcaccgtcctcaccattgcccaccggctcaacaccatc
atggactacacaagggtgatcgtcttggacaaaggagaaatccaggagtacggcgcccca
tcggacctcctgcagcagagaggtcttttctacagcatggccaaagacgccggcttggtg
tga |
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