Pan troglodytes (chimpanzee): 454454 Help Entry 454454            CDS       T01005                                  Symbol PLD2 Name (RefSeq) phospholipase D2 isoform X2   KO K01115   phospholipase D1/2 [EC:3.1.4.4] Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr00564   Glycerophospholipid metabolism ptr00565   Ether lipid metabolism ptr01100   Metabolic pathways ptr04014   Ras signaling pathway ptr04024   cAMP signaling pathway ptr04071   Sphingolipid signaling pathway ptr04072   Phospholipase D signaling pathway ptr04144   Endocytosis ptr04666   Fc gamma R-mediated phagocytosis ptr04724   Glutamatergic synapse ptr04912   GnRH signaling pathway ptr04928   Parathyroid hormone synthesis, secretion and action ptr05200   Pathways in cancer ptr05208   Chemical carcinogenesis - reactive oxygen species ptr05212   Pancreatic cancer ptr05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ptr00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     454454 (PLD2)    00565 Ether lipid metabolism     454454 (PLD2)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     454454 (PLD2)    04072 Phospholipase D signaling pathway     454454 (PLD2)    04071 Sphingolipid signaling pathway     454454 (PLD2)    04024 cAMP signaling pathway     454454 (PLD2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     454454 (PLD2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     454454 (PLD2)   09152 Endocrine system    04912 GnRH signaling pathway     454454 (PLD2)    04928 Parathyroid hormone synthesis, secretion and action     454454 (PLD2)   09156 Nervous system    04724 Glutamatergic synapse     454454 (PLD2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     454454 (PLD2)    05208 Chemical carcinogenesis - reactive oxygen species     454454 (PLD2)    05231 Choline metabolism in cancer     454454 (PLD2)   09162 Cancer: specific types    05212 Pancreatic cancer     454454 (PLD2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ptr04131]     454454 (PLD2) Enzymes [BR:ptr01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.4  phospholipase D      454454 (PLD2) Membrane trafficking [BR:ptr04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     454454 (PLD2)  Endosome - Golgi transport   Others    Others     454454 (PLD2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLDc PX PLDc_2 PH PH_2 Motif Other DBs NCBI-GeneID:  454454 NCBI-ProteinID:  XP_016786773 Ensembl:  ENSPTRG00000008610 VGNC:  9528 UniProt:  K7BNT4 A0A6D2WCR5 LinkDB All DBs Position 19:15322142..15338463 Genome browser AA seq 933 aa AA seqDB search MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFA PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVL MSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYR NYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV KDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQAR WWAQEITELAQGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIF ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSE SAASQPPTLCPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQ CTTVQVLRSVDRWSAGTLENSILNAYLHTIRESRHFLYIENQFFISCSDGRTVLNKVGDE IVDRILKAHKQGQCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR LKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLL GKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFSVILGANTRPDLDLRDPICD DFFQLWQDTAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQ GHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT NT seq 2802 nt NT seq  +upstreamnt  +downstreamnt atgacggcgacccctgagagcctcttccccactggggacgaactggactccagccagctc cagatggagtccgatgaggtggacaccctgaaggagggagaggacccagccgaccggatg cacccgtttctggccatctatgagcttcagtctctgaaagtgcaccccttggtgttcgca cctggggtccctgtcacagcccaggtggtgggcaccgaaagatataccagcggatccaag gtgggaacctgcactctgtattctgtccgcttgactcacggcgacttttcctggacaacc aagaagaaataccgtcattttcaggagctgcatcgggacctcctgagacacaaagtcttg atgagtctgctccctctggctcgatttgccgttgcctattctccagcccgagatgcaggc aacagagagatgccctctctaccccgggcaggtcctgagggctccaccagacatgcagcc agcaaacagaaatacctggagaattacctcaaccgtctcttgaccatgtctttctatcgc aactaccatgccatgacagagttcctggaagtcagtcagctgtcctttatcccagacttg ggccgcaaaggactggaggggatgatccggaagcgctcaggtggccaccgtgttcctggc ctcacctgctgtggccgagaccaagtttgttatcgctggtccaagaggtggctggtggtg aaggactccttcctgctgtacatgtgcctcgagacgggtgccatctcatttgttcagctc tttgaccctggctttgaggtgcaagtcgggaaaaggagcacggaggcacggcacggcgtg cggatcgatacctcccacaggtccttgattctcaagtgcagcagctatcggcaggcacgg tggtgggcccaagagatcactgagctggcacagggcccaggcagagacttcctacagctg caccagcatgacagctacgccccaccccggcctgggaccttggcccggtggtttgtgaat ggggcaggttactttgctgctgtggcagatgccatccttcgagctcaagaggagattttc atcacagactggtggttgagtcctgaggtttacctgaagcgtccggcccattcagatgac tggagactggacattatgctcaagaggaaggcggaggagggtgtccgcgtgtctattctc ctgtttaaagaagtggaattggccttgggcatcaacagtggctatagcaagagggcgctg atgctgctgcaccccaacataaaggtgatgcgtcacccagaccaagtgacgttgtgggcc catcatgagaagctcctggtggtggaccaagtggtagcattcctggggggactggacctt gcctatggccgctgggatgacctgcactaccgactgactgaccttggagactcctctgaa tcagctgcctcccagcctcccaccctgtgcccagactcgccagccaccccagacctctct cacaaccaattcttctggctgggcaaggactacagcaatcttatcaccaaggactgggtg cagctggaccggcctttcgaagatttcattgacagggagacgacccctcggatgccatgg cgggacgttggggtggtcgtccatggcctaccagcccgggacctcgcccggcacttcatc cagcgctggaatttcaccaagaccaccaaggccaagtacaagactcccacatacccctac ctgcttcccaagtctaccagcacggccaatcagctccccttcacacttccaggagggcaa tgcaccaccgtacaggtcttgcgatcagtggaccgctggtcagcagggactctggagaac tccatcctcaatgcctacctgcacaccatcagggagagccggcacttcctctacattgag aatcagttcttcattagctgctcagatgggcggacggttctgaacaaggtgggcgatgag attgtggacagaatcctgaaggcccacaaacaggggcagtgttaccgagtctacgtgctt ttgcccttactccctggcttcgagggtgacatctccacgggcggtggcaactccatccag gccattctgcactttacttacaggaccctgtgtcgtggggagtattcaatcctgcatcgc cttaaagcagccatggggacagcatggcgggactatatttccatctgcgggcttcgtaca cacggagagctgggcgggcaccccgtctcggagctcatctacatccacagcaaggtgctc atcgcagatgaccggacagtcatcattggttctgcaaacatcaatgaccggagcttgctg gggaagcgggacagtgagctggccgtgctgatcgaggacacagagacggaaccatccctc atgaatggggcagagtatcaggcgggcaggtttgccttgagtctgcggaagcactgcttc agtgtgattcttggagcaaatacccggccagacttggatctccgagaccccatctgtgat gacttcttccagttgtggcaagacacggctgagagcaacgccaatatctatgagcagatc ttccgctgcctgccatccaatgccacgcgttccctgcggactctccgggagtacgtggcc gtggagcccttggccacggtcagtccccccttggctcggtctgagctcacccaggtccag ggccacctggtccacttccccctcaagttcctagaggatgagtctttgctgcccccgctg ggtagcaaggagggcatgatccccctagaagtgtggacatag

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