Pan troglodytes (chimpanzee): 454490
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Entry
454490 CDS
T01005
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00260
Glycine, serine and threonine metabolism
ptr00630
Glyoxylate and dicarboxylate metabolism
ptr00670
One carbon pool by folate
ptr01100
Metabolic pathways
ptr01200
Carbon metabolism
ptr01230
Biosynthesis of amino acids
ptr01240
Biosynthesis of cofactors
ptr01523
Antifolate resistance
ptr04981
Folate transport and metabolism
Module
ptr_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
454490 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
454490 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
454490 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
454490 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
454490 (SHMT1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
454490 (SHMT1)
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Gene cluster
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
454490
NCBI-ProteinID:
XP_054525752
Ensembl:
ENSPTRG00000008851
VGNC:
9609
UniProt:
A0A2I3SI33
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Position
19:48973290..49008042
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AA seq
483 aa
AA seq
DB search
MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAVVQALREEVESFASLFPLPGL
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NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atgacgatgccagtcaacggggcccacaaggatgctgacctgtggtcctcacatgacaag
atgctggcacaacccctcaaagacagtgatgttgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggattggagctgattgcctcggagaatttcgccagccgagca
gttttggaggccctaggctcttgcttaaataacaaatactctgaggggtacccgggccag
agatactatggcgggactgagtttattgatgaactggagaccctctgtcagaagcgagcc
ctgcaggcctataagctggacccacagtgctggggggtcaacgtccagccctactcaggc
tcccctgcaaacttcgctgtgtacactgccctggtggaaccccatgggcgcatcatgggc
ctggaccttccggatgggggccacctgacccatgggttcatgacagacaagaagaaaatc
tctgccacgtccatcttctttgaatctatgccctacaaggtgaacccagatactggctac
atcaactatgaccagctggaggagaacgcacgcctcttccacccgaagctgatcatcgca
ggaaccagctgctactcccgaaacctggaatatgcccggctacggaagattgcagatgag
aacggggcgtatctcatggcggacatggctcacatcagcgggctggtggcggctggcgtg
gtgccctccccatttgaacactgccatgtggtgaccaccaccactcacaagaccctgcga
ggctgccgagctggcatgatcttctacaggaaaggagtgaaaagtgtggatcccaagact
ggcaaagagattctgtacaacctggagtctcttatcaattctgctgtgttccctggcctg
cagggaggtccccacaaccacgccattgctggggttgctgtggcactgaagcaagctatg
actctggaatttaaagtttatcaacaccaggtggtggccaactgcagggctctgtctgag
gccctgacggagctgggctacaaaatagtcacaggtggttctgacaaccatttgatcctt
gtggatctccgttccaaaggcacagatggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgtccaggtgacagaagcgctctgcggcccagtgga
ctgcggctggggaccccagcactgacgtcccgtggacttttggaaaaagacttccaaaaa
gtagcccactttattcacagagggatagagctgaccctgcagatccagagcgacactggt
gtcagagccaccctgaaggagttcaaggagagactggcaggggataagtaccaggcggtt
gtgcaggctctccgggaggaggttgagagctttgcctctctcttccctctgcctggcctt
cctgacttctaa
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