Pan troglodytes (chimpanzee): 454651
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Entry
454651 CDS
T01005
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
454651 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ptr03032
]
454651 (TOP2A)
03036 Chromosome and associated proteins [BR:
ptr03036
]
454651 (TOP2A)
Enzymes [BR:
ptr01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
454651 (TOP2A)
DNA replication proteins [BR:
ptr03032
]
Eukaryotic type
DNA Topoisomerases
454651 (TOP2A)
Chromosome and associated proteins [BR:
ptr03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
454651 (TOP2A)
Centrosome formation proteins
Centriole proteins
454651 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
454651
NCBI-ProteinID:
XP_016787334
Ensembl:
ENSPTRG00000009122
VGNC:
9732
UniProt:
K7BYJ3
A0A6D2X6M8
LinkDB
All DBs
Position
19:27687909..27717366
Genome browser
AA seq
1531 aa
AA seq
DB search
MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRA
ATKTKFTMDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLSNKELKPQKSVVSDLE
ANDAKDSVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKG
TKRDPALNSGVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGESDDFHM
DFDSAVAPRAKSVRAKKPIKYLEESDEDDLF
NT seq
4596 nt
NT seq
+upstream
nt +downstream
nt
atggaagtgtcaccattgcagcccgtaaatgaaaatatgcaagtcaacaaaataaagaaa
aatgaagatgctaagaaaagactgtctgttgaaagaatctatcaaaagaaaacacaattg
gaacatattttgctccgcccagacacctacattggttctgtggaattagtgacccagcaa
atgtgggtttacgatgaagatgttggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcggacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgatccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgaaaagatgtatgtcccagctctc
atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtgacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataatatgggaaga
gctggtgagatggaactcaagcccttcaatggagaagattatacatgtatcacctttcag
cctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgttgcactaatggtc
agaagagcatatgatattgctggatccaccaaagatgtcaaagtctttcttaatggaaat
aaactgccagtaaaaggatttcgtagttatgtggacatgtatttgaaggacaagttggat
gaaactggtaactccttgaaagtaatacatgaacaagtaaaccacaggtgggaagtgtgt
ttaactatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacatcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtaaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaacccaagagctttggatcaacctgccaattgagtgaaaaatttatcaaa
gctgccattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataatagaatcaagggaattcccaaa
ctcgatgatgccaatgatgcagggggccgaaactccactgagtgtacgcttatcctgact
gagggagattcagccaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tatggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataagcag
atcatggaaaatgctgagattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattttacagccttcctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcaca
tcaaaggaagctaaagaatactttgcagatatgaaaagacatcgtatccagttcaaatat
tctggtcctgaagatgatgctgctatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactaatttcatggaggatagaagacaacgaaagttacttgggctt
cctgaggattacttgtatggacaaactaccacatatctgacatataatgacttcatcaac
aaggaacttatcttgttctcaaattctgataacgagagatctatcccttctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacttgcttcaaacggaatgacaagcga
gaggtaaaggttgcccaattagctggatcagtggctgaaatgtcttcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctaaacctcttgcagcccattggtcagtttggtaccaggctacatggtggcaaggattct
gctagtccacgatacatctttacaatgctcagctctttggctcgattgttatttccacca
aaagatgatcacacgttgaagtttttatatgatgacaaccagcgtgttgagcctgaatgg
tacattcctattattcccatggtgctgataaatggtgctgaaggaatcggtactgggtgg
tcctgcaaaatccccaactttgatgtgcgtgaaattgtaaataacatcaggcgtttgatg
gatggagaagaaccattgccaatgcttccaagttacaagaacttcaagggtactattgaa
gaactggctccaaatcaatatgtgattagtggtgaagtagctattcttaattctacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaagttcta
gaacccatgttgaatggcaccgagaagacacctcctctcataacagactatagggaatac
catacagataccactgtgaaatttgttgtgaagatgactgaagaaaaactggcagaggca
gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatatgacacggtgttggatattctaaga
gacttttttgaactcagacttaaatattatggattaagaaaagaatggctcctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg
ggatatgattcggatcctgtgaaggcctggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaacgaaaaggaaactgaaaagagtgactccgtaacagat
tctggaccaaccttcaactatcttcttgatatgcccctttggtatttaaccaaggaaaag
aaagatgaactctgcaggctaagaaatgaaaaagaacaagagctggacacattaaaaaga
aagagtccatcagatttgtggaaagaagacttggctacatttattgaagaattggaggct
gttgaagccaaggaaaaacaagatgaacaagtcggacttcctgggaaaggggggaaggcc
aaggggaaaaaaacacaaatggctgaagttttgccttctccacgtggtcaaagagtcatt
ccacgaataaccatagaaatgaaagcagaggcagaaaagaaaaataaaaagaaaattaag
aatgaaaatactgaaggaagccctcaagaagatggtgtggaactagaaggcctaaaacaa
agattagaaaagaaacagaaaagagaaccaggtacaaagacaaagaaacaaactacattg
ccatttaagccaatcaaaaaaggaaagaagagaaatccctggtctgattcagaatcagat
aggagcagtgacgaaagtaattttgatgtccctccacgagaaacagagccacggagagca
gcaacaaaaaccaaattcacaatggatttggattcagatgaagatttctcagattttgat
gaaaaaactgatgatgaagattttgtcccatcagatgctagtccacctaagaccaaaact
tccccaaaacttagtaacaaagaactgaaaccacagaaaagtgtcgtgtcagaccttgaa
gctaatgatgctaaggacagtgtaccactgtcttcaagccctcctgctacacatttccca
gatgaaactgaaattacaaacccagttcctaaaaagaatgtgacagtgaagaagacagca
gcaaaaagtcagtcttccacctccactaccggtgccaaaaaaagggctgccccaaaagga
actaaaagggatccagctttgaattctggtgtctctcagaagcctgatcctgccaaaacc
aagaatcgccgcaaaaggaagccatccacttctgatgattctgactctaattttgagaaa
attgtttcgaaagcagtcacaagcaagaaatccaagggggagagtgatgacttccatatg
gactttgactcagctgtggctcctcgggcaaaatctgtacgggcaaagaaacctataaag
tacctggaagagtcagatgaagatgatctgttttaa
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integrated database retrieval system
