Pan troglodytes (chimpanzee): 454769
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Entry
454769 CDS
T01005
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04140
Autophagy - animal
ptr04141
Protein processing in endoplasmic reticulum
ptr04210
Apoptosis
ptr04932
Non-alcoholic fatty liver disease
ptr05010
Alzheimer disease
ptr05012
Parkinson disease
ptr05014
Amyotrophic lateral sclerosis
ptr05016
Huntington disease
ptr05017
Spinocerebellar ataxia
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
454769 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
454769 (ERN1)
09143 Cell growth and death
04210 Apoptosis
454769 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
454769 (ERN1)
05012 Parkinson disease
454769 (ERN1)
05014 Amyotrophic lateral sclerosis
454769 (ERN1)
05016 Huntington disease
454769 (ERN1)
05017 Spinocerebellar ataxia
454769 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
454769 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
454769 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
454769 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
454769 (ERN1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
454769 (ERN1)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: Other
IRE family
454769 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
PQQ_3
Kdo
APH
CytochromB561_N
Motif
Other DBs
NCBI-GeneID:
454769
NCBI-ProteinID:
XP_016788238
Ensembl:
ENSPTRG00000009535
VGNC:
14501
LinkDB
All DBs
Position
19:complement(77170707..77261522)
Genome browser
AA seq
1014 aa
AA seq
DB search
MQQGVRTLTQELASATCPAGFLVLGGCRLPSVHRDFLEQVELWELHSWKIPHGFEIFGST
STVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLY
TLGSKNNEGLMKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAF
ADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGD
GLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRI
TKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDG
VTIGDKGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNL
PKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKD
MATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHPPGD
TAQDSELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSV
VIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHP
NVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLN
IVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEML
SEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDV
IARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLE
RGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLG
SLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFHEPPEPQPPVTPDAL
NT seq
3045 nt
NT seq
+upstream
nt +downstream
nt
atgcaacagggagtaaggactctcacccaagagctggcttctgccacttgccctgccggt
ttcttggtactgggaggctgcaggcttccttctgtgcaccgagacttccttgagcaagtg
gagctgtgggaattgcactcttggaagatcccgcatgggttcgagatttttggaagtacc
agcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctggatggaagtttgcat
gctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagatccagtcctgcag
gtcccaacacatgtggaagagcctgcctttctcccagatcctaatgatggcagcctgtat
acgcttggaagcaagaacaatgaaggcctgatgaaacttccttttaccatcccagaattg
gtgcaggcatccccgtgccgaagttcagatggaatcctctacatgggtaaaaagcaggac
atctggtatgttattgacctcctgaccggggagaagcagcagactttgtcatcggccttt
gcagatagtctctgcccatcaacctctcttctgtatcttgggcgaacagaatacaccatc
accatgtacgacaccaaaactcgagagctccggtggaatgccacctactttgactatgcg
gcctcgctgcctgaggacgacgtggactacaagatgtcccactttgtgtccaatggtgat
gggctggtggtgactgtggacagtgaatctggggacgtcctgtggatccaaaactacgcc
tcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcacatc
aatgtcgctgtggagaccctgcgctatctgaccttcatgtctggggaggtggggcgcatc
acaaagtggaagtacccgttccccaaggagacagaggccaagagcaagctgacgcccact
ctgtatgttgggaaatactctaccagcctctatgcctctccctcaatggtacacgagggg
gttgctgtcgtgccccgcggcagcacacttcctttgctggaagggccccagactgatggc
gtcaccattggggacaagggggagtgtgtgatcacgcccagcacggacgtcaagtttgat
cccggactcaaaagcaagaacaagctcaactacttgaggaattactggcttctgatagga
caccatgaaaccccactgtctgcgtctaccaagatgctggagagatttcccaacaatcta
cccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagctttgaggaagtt
atcaacctggttgaccagacttcagaaaacgcacctaccaccgtgtctcgggatgtggag
gagaagcccgcccatgcccctgcccggcccgaggcccccgtggactccatgcttaaggac
atggctaccatcatcctgagcaccttcctgctgattggctgggtggccttcatcatcacc
tatcccctgagcatgcatcagcagcagcagctgcagcaccagcagttccagaaggaactg
gagaagatccagctcctgcagcagcagcagcagcagctgcccttccacccacctggagac
acggctcaggacagcgagctcctggacacgtctggcccatactcagagagctcgggcacc
agcagccccagcacgtcccccagggcctccaaccactcgctctgctctggcagctctgcc
tccaaggctggcagcagcccctccctggaacaagacgatggagatgaggaaaccagcgtg
gtgatagttgggaaaatttccttctgtcccaaggatgtcctgggccatggagctgagggc
acaattgtgtaccggggcatgtttgacaaccgcgacgtggccgtgaagaggatcctcccc
gagtgttttagcttcgcagaccgtgaggtccagttgttgcgagaatcggatgagcacccg
aacgtgatccgctacttctgcacggagaaggaccggcaattccagtacattgccatcgag
ctgtgtgcagccaccctgcaagagtatgtggagcagaaggactttgcgcatctcggcctg
gagcccatcaccttgctgcagcagaccacctcgggcctggcccacctccactccctcaac
atcgttcacagagacctaaagccacacaacattctcatatccatgcccaatgcacacggc
aagatcaaggccatgatctccgactttggcctctgcaagaagctggcagtgggcagacac
agtttcagccgccgatctggggtgcctggcacagaaggctggatcgctccagagatgctg
agcgaagactgtaaggagaaccctacctacacggtggacatcttttctgcaggctgcgtc
ttttactacgtaatctctgagggcagccacccttttggcaagtccctgcagcggcaggcc
aacatcctcctgggtgcctgcagccttgactgcttgcacccagagaagcacgaagacgtc
attgcacgtgaattgatagagaagatgattgcgatggatcctcagaaacgcccctcagcg
aagcacgtgctcaaacacccgttcttctggagcctagagaagcagctccagttcttccag
gacgtgagcgacagaatagaaaaggaatccctggatggcccgatcgtgaagcagttggag
agaggcgggagagccgtggtgaagatggactggcgggagaacatcactgtccccctccag
acagacctgcgtaaattcaggacctataaaggtggttctgtcagagatctcctccgagcc
atgagaaataagaagcaccactaccgggagctgcctgcagaggtgcgggagacgctgggg
tccctccccgacgacttcgtgtgctacttcacatctcgcttcccccacctcctcgcacac
acctaccgggccatggagctgtgcagccacgagagactcttccagccctactacttccac
gagcccccagagccccagcccccagtgactccagacgccctctga
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