KEGG   Pan troglodytes (chimpanzee): 454921
Entry
454921            CDS       T01005                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04120  Ubiquitin mediated proteolysis
ptr04380  Osteoclast differentiation
ptr04630  JAK-STAT signaling pathway
ptr04668  TNF signaling pathway
ptr04910  Insulin signaling pathway
ptr04917  Prolactin signaling pathway
ptr04920  Adipocytokine signaling pathway
ptr04930  Type II diabetes mellitus
ptr04931  Insulin resistance
ptr04932  Non-alcoholic fatty liver disease
ptr04935  Growth hormone synthesis, secretion and action
ptr05160  Hepatitis C
ptr05164  Influenza A
ptr05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    454921 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    454921 (SOCS3)
   04668 TNF signaling pathway
    454921 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    454921 (SOCS3)
   04920 Adipocytokine signaling pathway
    454921 (SOCS3)
   04917 Prolactin signaling pathway
    454921 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    454921 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    454921 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    454921 (SOCS3)
   05164 Influenza A
    454921 (SOCS3)
   05168 Herpes simplex virus 1 infection
    454921 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    454921 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    454921 (SOCS3)
   04931 Insulin resistance
    454921 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ptr04121]
    454921 (SOCS3)
Ubiquitin system [BR:ptr04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     454921 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 454921
NCBI-ProteinID: XP_001157032
Ensembl: ENSPTRG00000052259
VGNC: 9641
UniProt: H2QDZ6 A0A6D2WCK4
LinkDB
Position
19:complement(91370457..91374032)
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgcagtgaccggcggcgaggcgaacctgctgctc
agtgccgagcccgccggcacctttctgatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtctgggaccaagaacctgcgcatccagtgtgaggggggc
agcttctctctgcagagcgatccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcaccactacatgccgccccctggagccccctccttcccctcgccacct
actgaaccctcctccgaggtgcccgagcagccgtctgcccagccactccctgggagtccc
cccagaagagcctattacatctactccgggggcgagaagatccccctggtgttgagccgg
cccctctcctccaacgtggccactcttcagcatctctgtcggaagaccgtcaacggccac
ctggactcctatgagaaagtcacccagctgccggggcccattcgggagttcctggaccag
tacgatgccccgctttaa

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