Pan troglodytes (chimpanzee): 455703
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Entry
455703 CDS
T01005
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04217
Necroptosis
ptr04380
Osteoclast differentiation
ptr04620
Toll-like receptor signaling pathway
ptr04621
NOD-like receptor signaling pathway
ptr04630
JAK-STAT signaling pathway
ptr04658
Th1 and Th2 cell differentiation
ptr04659
Th17 cell differentiation
ptr05145
Toxoplasmosis
ptr05160
Hepatitis C
ptr05161
Hepatitis B
ptr05162
Measles
ptr05164
Influenza A
ptr05165
Human papillomavirus infection
ptr05167
Kaposi sarcoma-associated herpesvirus infection
ptr05168
Herpes simplex virus 1 infection
ptr05169
Epstein-Barr virus infection
ptr05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
455703 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
455703 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
455703 (TYK2)
04621 NOD-like receptor signaling pathway
455703 (TYK2)
04658 Th1 and Th2 cell differentiation
455703 (TYK2)
04659 Th17 cell differentiation
455703 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
455703 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
455703 (TYK2)
05160 Hepatitis C
455703 (TYK2)
05171 Coronavirus disease - COVID-19
455703 (TYK2)
05164 Influenza A
455703 (TYK2)
05162 Measles
455703 (TYK2)
05168 Herpes simplex virus 1 infection
455703 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
455703 (TYK2)
05169 Epstein-Barr virus infection
455703 (TYK2)
05165 Human papillomavirus infection
455703 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
455703 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
455703 (TYK2)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
455703 (TYK2)
Protein kinases [BR:
ptr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
455703 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
455703
NCBI-ProteinID:
XP_024207000
Ensembl:
ENSPTRG00000010468
VGNC:
2210
UniProt:
K7B315
LinkDB
All DBs
Position
20:complement(13076537..13107151)
Genome browser
AA seq
1190 aa
AA seq
DB search
MPLRHWGMARGSKPFGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCHLALRHGIPLQEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR
FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP
TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK
AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP
YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSIRELGAALQGCLLRA
GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHMHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA
PECLPVGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPE
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADVLTVNPDSPASDPTVFHKRYL
KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE
HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQ
HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK
FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP
DKCPCEVYHLMKNCWETEASFRPNFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgcgccactgggggatggccaggggcagtaagccctttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcggg
gagccctgggtcactttcagtgagtcatcgctgacagctgaggaagtctgcatccacatt
gcacataaagttggtatcactcctccttgcttcaatctctttgccctcttcgatgctcag
gcccaagtctggttgcccccaaaccacatcctagagatccccagagacgcaagcctgatg
ctatatttccgcataaggttttatttccggaactggcatggcatgaatcctcgggaaccg
gctgtgtaccgttgtgggcccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaactcctggacccagcctcatttgagtacctctttgagcagggcaagcatgagttt
gtgaatgacgtggcatcactgtgggagctgtcgagcgaggaggagatccaccactttaag
aatgagagcctgggcatggcctttctgcacctctgtcacctcgctctccgccatggcatc
cccctgcaggaggtggccaagaagaccagcttcaaggactgcatcccgcgctccttccgt
cggcatatccggcagcacagcgccctgacccggctgcgccttcggaacgtcttccgcagg
ttcctgcgggacttccagccgggccgactctcccagcagatggtcatggtcaaataccta
gccacactcgagcggctggcaccccgcttcggcacagagcgtgtgcccgtgtgccacctg
aggctgctggcccaggccgagggggagccctgctacatccgggacagtggggtggcccct
acagaccctggccctgagtctgctgctgggcccccaacccacgaggtgctggtgacaggc
actggtggcatccagtggtggccagtagaggaggaggtgaacaaggaggagggttctagt
ggcagcagtggcaggaacccccaagccagcctgtttgggaagaaggccaaggctcacaag
gcagtcggccagccggcagacaggccgcgggagccactgtgggcctacttctgcgacttc
cgggacatcacccacgtggtgctgaaagagcactgtgtcagcatccaccggcaggacaac
aagtgcctggagctgagcttgccttcccgggctgcggcgctgtccttcgtgtcgctggtg
gacggctatttccgcctgacggccgactccagccactacctgtgccacgaggtggctccc
ccacggctggtgatgagcatccgggatgggatccacggacccctgctggagccatttgtg
caggccaagctgcggcccgaggacggcctgtacctcattcactggagcaccagccacccc
taccgcctgatcctcacagtggcccagcgtagccaggcaccagacggcatgcagagcttg
cggctccgaaagttccccattgagcagcaggacggggccttcgtgctggagggctggggc
cggtccttccccagcattcgggaacttggggctgccttgcagggctgcttgctgagggcc
ggggatgactgcttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaat
ctcatcatcatgcggggggctcgggccagccccaggacactcaacctcagccagctcagc
ttccaccgggttgaccagaaggagatcacccagctgtcccacttgggccagggcacaagg
accaacgtgtatgagggccgcctgcgagtggagggcagcggggaccctgaggagggcaag
atggatgacgaggaccccctcgtgcctggcagggaccgtgggcaggagctacgagtggtg
ctcaaagtgctggaccctagtcaccatgacatcgccctggccttctacgagacagccagc
ctcatgagccaggtctcccacatgcacctggccttcgtgcatggcgtctgtgtgcgcggc
cctgaaaatatcatggtgacagagtacgtggagcacggacccctggatgtgtggctgcgg
agggagcggggccatgtgcccatggcttggaagatggtggtggcccagcagctggccagc
gccctcagctacctggagaacaagaacctggttcatggtaatgtgtgtggccggaacatc
ctgctggcccggctggggttggcagagggcaccagccccttcatcaagctgagtgatcct
ggcgtgggcctgggcgccctctccagggaggagcgggtggagaggatcccctggctggcc
cccgaatgcctaccagttggggccaacagcctaagcaccgccatggacaagtgggggttt
ggcgccaccctcctggagatctgctttgacggagaggcccctctgcagagccgcagtccc
tccgagaaggagcatttctaccagaggcagcaccggctgcctgagccctcctgcccagag
ctggccacactcaccagccagtgtctgacctatgagccaacccagaggccatcattccgc
accatcctgcgtgacctcacccggctgcagccccacactcttccagatcttgctgacgtc
ttgactgtgaacccggactcaccggcgtcggaccctacggttttccacaagcgctacttg
aaaaagatccgagatctgggcgagggtcacttcggcaaggtcagcttgtactgctacgat
ccgaccaacgacggcactggcgagatggtggcggtgaaagccctcaaggcagactgcggc
ccccagcaccgctcgggctggaagcaggagattgacattctgcgcacgctctaccacgag
cacatcatcaagtacaagggctgctgcgaggaccaaggcgagaagtcgctgcagctggtc
atggagtacgtgcccctgggcagcctccgagactacctgccccggcacagcgtcgggctg
gcccagctgctgctcttcgcccagcagatctgcgagggcatggcctatctgcacgctcag
cactacatccaccgagacctagccgcgcgcaacgtgctgctggacaacgacaggctggtc
aagatcggggactttggcctagccaaggccgtgcccgaaggccacgagtactaccgcgtg
cgcgaggatggggacagccccgtgttctggtatgccccagagtgcctgaaggagtataag
ttctactatgcgtcagatgtctggtccttcggggtgaccctgtatgagctgctgacgcac
tgtgactccagccagagcccccccacgaaattccttgagctcataggcattgctcagggt
cagatgacagttctgagactcactgagttgctggaacgaggggagaggctgccacggccc
gacaaatgtccctgtgaggtctatcatctcatgaagaactgctgggagacagaggcgtcc
tttcgcccaaacttcgagaacctcatacccattctgaagacagtccatgagaagtaccaa
ggccaggccccttcagtgtttagcgtgtgctga
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integrated database retrieval system
