Pan troglodytes (chimpanzee): 456624
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Entry
456624 CDS
T01005
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00280
Valine, leucine and isoleucine degradation
ptr00650
Butanoate metabolism
ptr01100
Metabolic pathways
ptr04146
Peroxisome
Module
ptr_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
456624 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
456624 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
456624 (HMGCL)
Enzymes [BR:
ptr01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
456624 (HMGCL)
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GFIT
Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
456624
NCBI-ProteinID:
XP_001166273
Ensembl:
ENSPTRG00000000339
VGNC:
1261
UniProt:
H2PYB3
A0A6D2WYU0
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Position
1:207180952..207219772
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AA seq
325 aa
AA seq
DB search
MAAMRKALPRRLVGLASLRAVSTSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLV
DMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAG
AKEVVIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKI
SPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQ
ALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLL
EAGNFICQALNRKTSSKVAQATCKL
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcagcaatgaggaaggcgcttccgcggcgactggtgggcttggcgtccctccgggct
gtcagcacctcatctatgggcactttaccaaagcgggtgaaaattgtggaagttggtccc
cgagatggactacaaaatgaaaagaatatcgtatctactccagtgaaaatcaagctggta
gacatgctttctgaagcaggactctctgttatagaaaccaccagctttgtgtctcctaag
tgggttccccagatgggtgaccacactgaagtcttgaagggcattcagaagtttcctggc
atcaactacccagtcctgaccccaaatttgaaaggcttcgaggcagcggttgctgctgga
gccaaggaagtagtcatctttggagctgcctcagagctcttcaccaagaagaacatcaat
tgttccatagaggagagttttcagaggtttgacgcaatcctgaaggcagcacagtcagcc
aatatttctgtgcgggggtacgtctcctgtgctcttggctgcccttatgaagggaagatc
tccccagctaaagtagctgaggtcaccaagaagttctactcaatgggctgctacgagatc
tccctgggggacaccattggtgtgggcaccccagggatcatgaaagacatgctgtctgct
gtcatgcaggaagtgcctctggctgccctggctgtccactgccatgacacctatggccaa
gccctggccaacaccttgatggccctgcagatgggagtgagtgtcgtggactcttctgtg
gcaggacttggaggctgtccctacgcacagggggcatcaggaaacttggccacggaagac
ctggtctacatgctagagggcttgggcattcacacgggtgtgaatctccagaagcttctg
gaagctggaaactttatctgtcaagccctgaacagaaaaactagctccaaagtggctcag
gctacctgtaaactctga
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