Pan troglodytes (chimpanzee): 457076
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Entry
457076 CDS
T01005
Symbol
VAV3
Name
(RefSeq) guanine nucleotide exchange factor VAV3 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04015
Rap1 signaling pathway
ptr04024
cAMP signaling pathway
ptr04062
Chemokine signaling pathway
ptr04510
Focal adhesion
ptr04650
Natural killer cell mediated cytotoxicity
ptr04660
T cell receptor signaling pathway
ptr04662
B cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04666
Fc gamma R-mediated phagocytosis
ptr04670
Leukocyte transendothelial migration
ptr04810
Regulation of actin cytoskeleton
ptr05135
Yersinia infection
ptr05205
Proteoglycans in cancer
ptr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
457076 (VAV3)
04024 cAMP signaling pathway
457076 (VAV3)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
457076 (VAV3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
457076 (VAV3)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
457076 (VAV3)
04660 T cell receptor signaling pathway
457076 (VAV3)
04662 B cell receptor signaling pathway
457076 (VAV3)
04664 Fc epsilon RI signaling pathway
457076 (VAV3)
04666 Fc gamma R-mediated phagocytosis
457076 (VAV3)
04670 Leukocyte transendothelial migration
457076 (VAV3)
04062 Chemokine signaling pathway
457076 (VAV3)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
457076 (VAV3)
09171 Infectious disease: bacterial
05135 Yersinia infection
457076 (VAV3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
457076 (VAV3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH2
SH3_9
SH3_1
SOS1_NGEF_PH
C1_1
PH
RHG20_PH
CDC24
Filamin
LZ3wCH
PH_10
SH2_1
zf-RING-like
Prok-RING_1
C1_2
zf-RING_16
Motif
Other DBs
NCBI-GeneID:
457076
NCBI-ProteinID:
XP_016779088
Ensembl:
ENSPTRG00000001024
VGNC:
1722
UniProt:
A0A2I3REC5
LinkDB
All DBs
Position
1:123365351..123767016
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AA seq
875 aa
AA seq
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MEPWKQCAQWLIHCKVLPANHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEI
NLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRTPI
ALATGIRPFPTEESINDEDIYKGLPDLIDETLVEDEEDLYDCVYGEDEGGEVYEDLMKAE
EAHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPE
LVKLHRNLMQEIHDSIVNKNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKE
DVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDSTEKANLKLALDA
MKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQER
HIFLFDLAVIVCKRKGDNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGL
EFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHDFKMHTFTRVTSCKVCQMLLRGTFYQ
GYLCFKCGARAHKECLGRVDNCGRVNSGEQGTLKLPEKRTNGLRRTPKQVDPGLPKMQVI
RNYSGTPPPALHEGPPLHLQAGDTVELLKGDAHSLFWQGRNLASGEVGFFPSDAVKPCPC
VPKPVDYSCQPWYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIK
ILTRDGFFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEHSAGQRGNRA
GNSSPSLFCGFSFVTPPDYSFVPPSSTPFWSVLSPKVLGIAIARYDFCARDMRELSLLKG
DVVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE
NT seq
2628 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtggaagcagtgcgcgcagtggctcatccattgcaaggtgctgcccgccaac
caccgggtgacctgggactcggctcaggtgttcgacctggcgcagaccctccgcgatgga
gtcctgctctgccagctgcttaacaacctccgggcgcactccatcaacctgaaggagatc
aacctgaggccgcagatgtcccagtttctctgtttgaagaacataaggacatttctcacg
gcctgttgtgagacgtttggaatgaggaaaagtgaacttttcgaggcatttgacctgttt
gatgttcgtgactttggaaaggttatagaaacattatcacgactttctcgaacacctata
gcattggccacaggaatcaggcccttcccaacagaagaaagcattaatgatgaagacatc
tacaaaggccttcctgatttaatagatgaaacccttgtggaagatgaagaagatctctat
gactgtgtttatggggaagatgaaggtggagaagtctatgaggacttaatgaaggcagag
gaagcacatcagcccaaatgtccagaaaatgatatacgaagttgttgtctagcagaaatt
aagcagacagaagaaaaatatacagaaactttggagtcaatagaaaaatatttcatggca
ccactaaaaagatttctgacagcagcagaatttgattcagtattcatcaacattcctgaa
cttgtaaaacttcatcggaacctaatgcaagagattcatgattccattgtaaataaaaat
gaccagaacttgtaccaagtttttattaactacaaggaaagattggttatttacgggcag
tactgcagtggagtggagtcagccatctctagtttagactacatttctaagacaaaagaa
gatgtcaaactgaaattagaggaatgttccaaaagagcaaataatgggaaatttacactt
cgagacttgcttgtggttcctatgcaacgtgttttaaagtaccaccttctcctccaggaa
ctggtcaaacataccactgattcgactgagaaggcaaatctgaaactggctcttgatgcc
atgaaggacttggcacaatatgtgaatgaagtgaaaagagataatgagacccttcgtgaa
attaaacagtttcagctatctatagagaatttgaaccaaccagttttgctttttggacga
cctcagggagatggtgaaattcgaataaccactctagacaagcataccaaacaagaaagg
catatcttcttatttgatttggcagtgatcgtatgtaagagaaaaggtgataactatgaa
atgaaggaaataatagatcttcagcagtacaagatagccaataatcctacaaccgataaa
gaaaataaaaagtggtcttatggcttctacctcatccatacccaaggacaaaatgggtta
gaattttattgcaaaacaaaagatttaaagaagaaatggctagaacagtttgaaatggct
ttgtctaacataaggccagactatgcagactccaatttccacgacttcaagatgcatacc
ttcactcgagtcacatcctgcaaagtctgccagatgctcctgaggggaacattttatcaa
ggctatttatgttttaagtgtggagcgagagcacacaaagaatgtttgggaagagtagac
aattgtggcagagttaattctggtgaacaagggacactcaaactaccagagaaacggacc
aatggactgcgaagaactcctaaacaggtggatccaggtttaccaaagatgcaggtcatt
aggaactattctggaacaccacccccagctctgcatgaaggaccccctttacacctccag
gccggggataccgttgaacttctgaaaggagatgcacacagtctgttttggcagggcaga
aatttggcatctggagaggttggattttttccaagtgatgcagtcaagccttgcccatgt
gtgcccaaaccagtagattattcttgccaaccctggtatgctggagcaatggaaagattg
caagcagagactgaacttattaacagggtaaatagtacttaccttgtgaggcacaggacc
aaagagtcaggagaatatgcaattagcattaagtacaataatgaagcaaagcacatcaag
attttaacaagagatggtttttttcacattgcagaaaatagaaaatttaaaagtttaatg
gaacttgtggagtactacaagcatcattctctcaaggaagggttcagaaccttagataca
actctgcagtttccatacaaggagccagaacattcagctggacagaggggtaatagagca
ggcaacagctccccctctttgttctgtggcttttcttttgtaactcctccagactacagc
tttgttcccccttcttccactcctttctggtcagtgttaagtccaaaagtgctgggcatt
gccatcgctcggtatgacttctgtgcaagagatatgagagagttgtccttgttgaaagga
gatgtggtgaagatttacacaaagatgagtgcaaatggctggtggagaggagaagtaaat
ggcagggtgggctggtttccatccacatatgtggaagaggatgaataa
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