KEGG   Pan troglodytes (chimpanzee): 457093
Entry
457093            CDS       T01005                                 
Symbol
GNAI3
Name
(RefSeq) guanine nucleotide-binding protein G(I) subunit alpha-3
  KO
K04630  guanine nucleotide-binding protein G(i) subunit alpha
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04015  Rap1 signaling pathway
ptr04022  cGMP-PKG signaling pathway
ptr04024  cAMP signaling pathway
ptr04062  Chemokine signaling pathway
ptr04071  Sphingolipid signaling pathway
ptr04081  Hormone signaling
ptr04082  Neuroactive ligand signaling
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04360  Axon guidance
ptr04371  Apelin signaling pathway
ptr04540  Gap junction
ptr04611  Platelet activation
ptr04670  Leukocyte transendothelial migration
ptr04713  Circadian entrainment
ptr04723  Retrograde endocannabinoid signaling
ptr04724  Glutamatergic synapse
ptr04725  Cholinergic synapse
ptr04726  Serotonergic synapse
ptr04727  GABAergic synapse
ptr04728  Dopaminergic synapse
ptr04730  Long-term depression
ptr04914  Progesterone-mediated oocyte maturation
ptr04915  Estrogen signaling pathway
ptr04916  Melanogenesis
ptr04921  Oxytocin signaling pathway
ptr04923  Regulation of lipolysis in adipocytes
ptr04924  Renin secretion
ptr04926  Relaxin signaling pathway
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04934  Cushing syndrome
ptr04935  Growth hormone synthesis, secretion and action
ptr04971  Gastric acid secretion
ptr05012  Parkinson disease
ptr05030  Cocaine addiction
ptr05032  Morphine addiction
ptr05034  Alcoholism
ptr05133  Pertussis
ptr05142  Chagas disease
ptr05145  Toxoplasmosis
ptr05163  Human cytomegalovirus infection
ptr05170  Human immunodeficiency virus 1 infection
ptr05200  Pathways in cancer
ptr05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    457093 (GNAI3)
   04371 Apelin signaling pathway
    457093 (GNAI3)
   04071 Sphingolipid signaling pathway
    457093 (GNAI3)
   04024 cAMP signaling pathway
    457093 (GNAI3)
   04022 cGMP-PKG signaling pathway
    457093 (GNAI3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    457093 (GNAI3)
   04081 Hormone signaling
    457093 (GNAI3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    457093 (GNAI3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    457093 (GNAI3)
   04670 Leukocyte transendothelial migration
    457093 (GNAI3)
   04062 Chemokine signaling pathway
    457093 (GNAI3)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    457093 (GNAI3)
   04915 Estrogen signaling pathway
    457093 (GNAI3)
   04914 Progesterone-mediated oocyte maturation
    457093 (GNAI3)
   04921 Oxytocin signaling pathway
    457093 (GNAI3)
   04926 Relaxin signaling pathway
    457093 (GNAI3)
   04935 Growth hormone synthesis, secretion and action
    457093 (GNAI3)
   04928 Parathyroid hormone synthesis, secretion and action
    457093 (GNAI3)
   04916 Melanogenesis
    457093 (GNAI3)
   04924 Renin secretion
    457093 (GNAI3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    457093 (GNAI3)
  09154 Digestive system
   04971 Gastric acid secretion
    457093 (GNAI3)
  09156 Nervous system
   04724 Glutamatergic synapse
    457093 (GNAI3)
   04727 GABAergic synapse
    457093 (GNAI3)
   04725 Cholinergic synapse
    457093 (GNAI3)
   04728 Dopaminergic synapse
    457093 (GNAI3)
   04726 Serotonergic synapse
    457093 (GNAI3)
   04730 Long-term depression
    457093 (GNAI3)
   04723 Retrograde endocannabinoid signaling
    457093 (GNAI3)
  09158 Development and regeneration
   04360 Axon guidance
    457093 (GNAI3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    457093 (GNAI3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    457093 (GNAI3)
   05207 Chemical carcinogenesis - receptor activation
    457093 (GNAI3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    457093 (GNAI3)
   05163 Human cytomegalovirus infection
    457093 (GNAI3)
  09171 Infectious disease: bacterial
   05133 Pertussis
    457093 (GNAI3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    457093 (GNAI3)
   05142 Chagas disease
    457093 (GNAI3)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    457093 (GNAI3)
  09165 Substance dependence
   05030 Cocaine addiction
    457093 (GNAI3)
   05032 Morphine addiction
    457093 (GNAI3)
   05034 Alcoholism
    457093 (GNAI3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    457093 (GNAI3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ptr04147]
    457093 (GNAI3)
   04031 GTP-binding proteins [BR:ptr04031]
    457093 (GNAI3)
Exosome [BR:ptr04147]
 Exosomal proteins
  Proteins found in most exosomes
   457093 (GNAI3)
GTP-binding proteins [BR:ptr04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    457093 (GNAI3)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc TniB FtsK_SpoIIIE AAA_29
Other DBs
NCBI-GeneID: 457093
NCBI-ProteinID: XP_513624
Ensembl: ENSPTRG00000001055
VGNC: 8327
UniProt: H2PZK9 A0A6D2X1V2
LinkDB
Position
1:complement(121896905..121943876)
AA seq 354 aa
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT
PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK
TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA
AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgggctgcacgttgagcgccgaagacaaggcggcagtggagcgaagcaagatgatcgac
cgcaatttacgggaggacggggaaaaagcggccaaagaagtgaagctgctgctactcggt
gctggagaatctggtaaaagtaccattgtgaaacagatgaaaatcattcatgaggatggc
tattcagaggatgaatgtaaacaatataaagtagttgtctacagcaatactatacagtcc
atcattgcaatcataagagccatgggacggctaaagattgactttggggaagctgccagg
gcagatgatgcccggcaattatttgttttagctggcagtgctgaagaaggagtcatgact
ccagaactagcaggagtgattaaacggttatggcgagatggtggggtacaagcttgcttc
agcagatccagggaatatcagctcaatgattctgcttcatattatctaaatgatctggat
agaatatcccagtctaactacattccaactcagcaagatgttcttcggacgagagtgaag
accacaggcattgtagaaacacatttcaccttcaaagacctatacttcaagatgtttgat
gtaggtggccaaagatcagaacgaaaaaagtggattcactgttttgagggagtgacagca
attatcttctgtgtggccctcagtgattatgaccttgttctggctgaggacgaggagatg
aaccgaatgcatgaaagcatgaaactgtttgacagcatttgtaataacaaatggtttaca
gaaacttcaatcattctcttccttaacaagaaagacctttttgaggaaaaaataaagagg
agtccattaactatctgttatccagaatacacaggttccaatacatatgaagaggcagct
gcctatattcaatgccagtttgaagatctgaacagaagaaaagataccaaggagatctat
acccacttcacctgtgccacagacacgaagaatgtgcagtttgtttttgatgctgttaca
gatgtcatcattaaaaacaacttaaaggaatgtggactttattga

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