KEGG   Pan troglodytes (chimpanzee): 457742
Entry
457742            CDS       T01005                                 
Symbol
TGFB2
Name
(RefSeq) transforming growth factor beta-2 proprotein isoform X1
  KO
K13376  transforming growth factor beta-2
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04010  MAPK signaling pathway
ptr04060  Cytokine-cytokine receptor interaction
ptr04068  FoxO signaling pathway
ptr04110  Cell cycle
ptr04218  Cellular senescence
ptr04350  TGF-beta signaling pathway
ptr04380  Osteoclast differentiation
ptr04390  Hippo signaling pathway
ptr04933  AGE-RAGE signaling pathway in diabetic complications
ptr05140  Leishmaniasis
ptr05142  Chagas disease
ptr05144  Malaria
ptr05145  Toxoplasmosis
ptr05146  Amoebiasis
ptr05152  Tuberculosis
ptr05161  Hepatitis B
ptr05166  Human T-cell leukemia virus 1 infection
ptr05200  Pathways in cancer
ptr05205  Proteoglycans in cancer
ptr05206  MicroRNAs in cancer
ptr05210  Colorectal cancer
ptr05211  Renal cell carcinoma
ptr05212  Pancreatic cancer
ptr05220  Chronic myeloid leukemia
ptr05225  Hepatocellular carcinoma
ptr05226  Gastric cancer
ptr05321  Inflammatory bowel disease
ptr05323  Rheumatoid arthritis
ptr05410  Hypertrophic cardiomyopathy
ptr05414  Dilated cardiomyopathy
ptr05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    457742 (TGFB2)
   04350 TGF-beta signaling pathway
    457742 (TGFB2)
   04390 Hippo signaling pathway
    457742 (TGFB2)
   04068 FoxO signaling pathway
    457742 (TGFB2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    457742 (TGFB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    457742 (TGFB2)
   04218 Cellular senescence
    457742 (TGFB2)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    457742 (TGFB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    457742 (TGFB2)
   05206 MicroRNAs in cancer
    457742 (TGFB2)
   05205 Proteoglycans in cancer
    457742 (TGFB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    457742 (TGFB2)
   05212 Pancreatic cancer
    457742 (TGFB2)
   05225 Hepatocellular carcinoma
    457742 (TGFB2)
   05226 Gastric cancer
    457742 (TGFB2)
   05220 Chronic myeloid leukemia
    457742 (TGFB2)
   05211 Renal cell carcinoma
    457742 (TGFB2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    457742 (TGFB2)
   05161 Hepatitis B
    457742 (TGFB2)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    457742 (TGFB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    457742 (TGFB2)
   05144 Malaria
    457742 (TGFB2)
   05145 Toxoplasmosis
    457742 (TGFB2)
   05140 Leishmaniasis
    457742 (TGFB2)
   05142 Chagas disease
    457742 (TGFB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    457742 (TGFB2)
   05321 Inflammatory bowel disease
    457742 (TGFB2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    457742 (TGFB2)
   05414 Dilated cardiomyopathy
    457742 (TGFB2)
   05415 Diabetic cardiomyopathy
    457742 (TGFB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    457742 (TGFB2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ptr04052]
    457742 (TGFB2)
   00536 Glycosaminoglycan binding proteins [BR:ptr00536]
    457742 (TGFB2)
Cytokines and neuropeptides [BR:ptr04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   457742 (TGFB2)
Glycosaminoglycan binding proteins [BR:ptr00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   457742 (TGFB2)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta CBM96 SPEG_u2
Other DBs
NCBI-GeneID: 457742
NCBI-ProteinID: XP_001172158
Ensembl: ENSPTRG00000001992
VGNC: 7006
UniProt: H2Q153
LinkDB
Position
1:complement(30673297..30771750)
AA seq 442 aa
MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP
EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETVCPV
VTTPSGSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVF
RLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLH
HKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRK
KNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW
KWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILY
YIGKTPKIEQLSNMIVKSCKCS
NT seq 1329 nt   +upstreamnt  +downstreamnt
atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtcgcgctcagc
ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc
cgcgggcagatcctgagcaagctgaagctcaccagtcccccagaagactatcctgagccc
gaggaagtccccccggaggtgatttccatctacaacagcaccagggacttgctccaggag
aaggcgagccggagggcggccgcctgcgagcgcgagaggagcgacgaagagtactacgcc
aaggaggtttacaaaatagacatgccgcccttcttcccctccgaaactgtctgcccagtt
gttacaacaccctctggctcagtgggcagcttgtgctccagacagtcccaggtgctctgt
gggtaccttgatgccatcccgcccactttctacagaccctacttcagaattgttcgattt
gacgtctcagcaatggagaagaatgcttccaatttggtgaaagcagagttcagagtcttt
cgtttgcagaacccaaaagccagagtgcctgaacaacggattgagctctatcagattctc
aagtccaaagatttaacatctccaacccagcgctacatcgacagcaaagttgtgaaaaca
agagcagaaggcgaatggctctccttcgatgtaactgatgctgttcatgaatggcttcac
cataaagacaggaacctgggatttaaaataagcttacactgtccctgctgcacttttgta
ccatctaataattacatcatcccaaataaaagtgaagaactagaagcaagatttgcaggt
attgatggcacctccacatataccagtggtgatcagaaaactataaagtccactaggaaa
aaaaacagtgggaagaccccacatctcctgctaatgttattgccctcctacagacttgag
tcacaacagaccaaccggcggaagaagcgtgctttggatgcagcctattgctttagaaat
gtgcaggataattgctgcctacgtccactttacattgatttcaagagggatctagggtgg
aaatggatacacgaacccaaagggtacaatgccaacttctgtgctggagcatgcccgtat
ttatggagttcagacactcagcacagcagggtcctgagcttatataataccataaatcca
gaagcatctgcttctccttgctgcgtgtcccaagatttagaacctctaaccattctctac
tacattggcaaaacacccaagattgaacagctttctaatatgattgtaaagtcttgcaaa
tgcagctaa

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