KEGG   Pan troglodytes (chimpanzee): 458607
Entry
458607            CDS       T01005                                 
Symbol
ITGB2
Name
(RefSeq) integrin beta-2 isoform X2
  KO
K06464  integrin beta 2
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04015  Rap1 signaling pathway
ptr04145  Phagosome
ptr04390  Hippo signaling pathway
ptr04514  Cell adhesion molecule (CAM) interaction
ptr04517  IgSF CAM signaling
ptr04518  Integrin signaling
ptr04610  Complement and coagulation cascades
ptr04613  Neutrophil extracellular trap formation
ptr04650  Natural killer cell mediated cytotoxicity
ptr04670  Leukocyte transendothelial migration
ptr04810  Regulation of actin cytoskeleton
ptr05133  Pertussis
ptr05134  Legionellosis
ptr05140  Leishmaniasis
ptr05144  Malaria
ptr05146  Amoebiasis
ptr05150  Staphylococcus aureus infection
ptr05152  Tuberculosis
ptr05166  Human T-cell leukemia virus 1 infection
ptr05323  Rheumatoid arthritis
ptr05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    458607 (ITGB2)
   04390 Hippo signaling pathway
    458607 (ITGB2)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    458607 (ITGB2)
   04517 IgSF CAM signaling
    458607 (ITGB2)
   04518 Integrin signaling
    458607 (ITGB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    458607 (ITGB2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    458607 (ITGB2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    458607 (ITGB2)
   04613 Neutrophil extracellular trap formation
    458607 (ITGB2)
   04650 Natural killer cell mediated cytotoxicity
    458607 (ITGB2)
   04670 Leukocyte transendothelial migration
    458607 (ITGB2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    458607 (ITGB2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    458607 (ITGB2)
   05134 Legionellosis
    458607 (ITGB2)
   05150 Staphylococcus aureus infection
    458607 (ITGB2)
   05152 Tuberculosis
    458607 (ITGB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    458607 (ITGB2)
   05144 Malaria
    458607 (ITGB2)
   05140 Leishmaniasis
    458607 (ITGB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    458607 (ITGB2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    458607 (ITGB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ptr04131]
    458607 (ITGB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ptr04147]
    458607 (ITGB2)
   04515 Cell adhesion molecules [BR:ptr04515]
    458607 (ITGB2)
   04090 CD molecules [BR:ptr04090]
    458607 (ITGB2)
Membrane trafficking [BR:ptr04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    458607 (ITGB2)
Exosome [BR:ptr04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   458607 (ITGB2)
Cell adhesion molecules [BR:ptr04515]
 Integrins
  Integrin beta subunits
   458607 (ITGB2)
CD molecules [BR:ptr04090]
 Proteins
  458607 (ITGB2)
SSDB
Motif
Pfam: Integrin_beta Integrin_B_tail EGF_integrin Integrin_b_cyt I-EGF_1 EGF_2 vWA_SIBA-E
Other DBs
NCBI-GeneID: 458607
NCBI-ProteinID: XP_016793883
Ensembl: ENSPTRG00000013993
VGNC: 3734
LinkDB
Position
22:complement(45531915..45578033)
AA seq 700 aa
MRGCAADDIMDPKSLAETQEDHNGGQKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDL
YYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNTHPDKLRN
PCPNKEKECQPPFAFRHVLKLTNNSSQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEE
IGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAH
KLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFL
DHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQEQSFVIR
ALGFTDIVTVRVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGYIGKNCECQTQGRS
SQELEGSCRKDNNSIICSGLGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVC
GGPGRGLCFCGKCRCHPGFEGSACQCERTTEGCLNPRRVECSGRGRCRCNVCECHSGYQL
PLCQECPGCPSPCGKYISCAECLKFEKGPFGKNCSAACPGLQLSNNPVKGRTCKERDSEG
CWVAYTLEQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHL
SDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
NT seq 2103 nt   +upstreamnt  +downstreamnt
atgaggggctgtgcggctgacgacatcatggaccccaagagcctcgctgaaacccaggaa
gaccacaatgggggccagaagcagctgtccccacaaaaagtgacgctttacctgcgacca
ggccaggcagcagcgttcaacgtgaccttccggcgggccaagggctaccccatcgacctg
tactacctgatggacctctcctactccatgcttgatgacctcaggaatgtcaagaagctg
gggggcgacctgctacgggccctcaacgagatcaccgagtccggccgcattggcttcggg
tccttcgtggacaagaccgtgctgccgttcgtgaacacgcaccctgataagctgcgaaac
ccatgccccaacaaggagaaggagtgccagcccccgtttgccttcaggcacgtgctgaag
ctgaccaacaactccagccagtttcagaccgaggtcgggaagcagctgatttccggaaac
ctggacgcacccgagggtgggctggatgccatgatgcaggtcgccgcctgcccggaggaa
atcggctggcgcaacgtcacgcggctgctggtgtttgccaccgatgacggcttccatttc
gcgggcgacgggaagctgggcgccatcctgacccccaacgacggccgctgtcacctggag
gacaacttgtacaagaggagcaacgaattcgactacccatcggtgggccagctggcgcac
aagctggctgaaaacaacatccagcccatcttcgcggtgaccagtaggatggtgaagacc
tacgagaaactcaccgagatcatccccaagtcagccgtgggggagctgtctgaggactcc
agcaatgtggtccatctcattaagaatgcttacaataaactctcctccagggtcttcctg
gatcacaacgccctccccgacaccctgaaagtcacctatgactccttctgcagcaatgga
gtgacgcacaggaaccagcccagaggtgactgtgatggcgtgcagatcaatgtcccgatc
accttccaggtgaaggtcacggccacagagtgtatccaggagcagtcatttgtcatccgg
gcgctgggcttcacggacatagtgaccgtgcgggtccttccccagtgcgagtgccggtgc
cgggaccagagcagagaccgcagcctctgccatggcaagggcttcttggagtgcggcatc
tgcaggtgtgacactggctacattgggaaaaactgtgagtgccagacacagggccggagc
agccaggagctggaaggaagctgccggaaggacaacaactccatcatctgctcagggctg
ggggactgtgtctgcgggcagtgcctgtgccacaccagcgacgtccccggcaagctgata
tacgggcagtactgcgagtgtgacaccatcaactgtgagcgctacaacggccaggtctgc
ggtggcccggggagggggctctgcttctgcgggaagtgccgctgccacccgggctttgag
ggctcagcgtgccagtgcgagaggaccaccgagggctgcctgaacccgcggcgtgttgag
tgcagtggccgtggccggtgccgctgcaacgtatgtgagtgccattcaggctaccagctg
cctctgtgccaggagtgccccggctgcccctcaccctgtggcaagtacatctcctgtgcc
gagtgcctgaagttcgaaaagggcccctttgggaagaactgcagcgcggcgtgtccgggc
ctgcagctgtcgaacaaccccgtgaagggcaggacctgcaaggagagggactcagagggc
tgctgggtggcctacacgctggagcagcaggacgggatggaccgctacctcatctatgtg
gatgagagccgagagtgcgtggcaggccccaacatcgctgccattgtcgggggcaccgtg
gcaggcatcgtgctgatcggcatcctcctgctggtcatctggaaggctctgatccacctg
agcgacctccgggagtacaggcgctttgagaaggagaagctcaagtcccagtggaacaat
gataatccccttttcaagagcgccaccacgacggtcatgaaccctaagtttgctgagagt
tag

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