Pan troglodytes (chimpanzee): 460113
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Entry
460113 CDS
T01005
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00020
Citrate cycle (TCA cycle)
ptr00480
Glutathione metabolism
ptr01100
Metabolic pathways
ptr01200
Carbon metabolism
ptr01210
2-Oxocarboxylic acid metabolism
ptr01230
Biosynthesis of amino acids
ptr04146
Peroxisome
ptr05230
Central carbon metabolism in cancer
Module
ptr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ptr_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
460113 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
460113 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
460113 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
460113 (IDH1)
Enzymes [BR:
ptr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
460113 (IDH1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
460113
NCBI-ProteinID:
XP_001141655
Ensembl:
ENSPTRG00000012865
VGNC:
1968
UniProt:
A0A6D2WM99
H2QJB5
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Position
13:complement(110471333..110490428)
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AA seq
414 aa
AA seq
DB search
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKRYKSQFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatcagtggtggttctgtggtagagatgcaaggagatgaaatgacacga
atcatttgggaattgattaaagagaaactcatttttccctacgtggaattggatctacat
agctatgatttaggcatagagaatcgtgacgccaccaacgaccaagtcaccaaggatgct
gcagaagctataaagaagtataatgttggcgtcaaatgtgccactatcactcctgatgag
aaaagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcaccatacga
aatattctgggtggcacggtcttcagagaagccattatctgcaaaaatatcccccggctt
gtgagtggatgggtaaaacctatcatcataggtcgtcatgcttatggggatcaatacaga
gcaactgattttgttgttcctgggcctggaaaagtagagataacctacacaccaagtgac
ggaacccaaaaggtgacatacctggtacataactttgaagagggtggtggtgttgccatg
gggatgtataatcaagataagtcaattgaagattttgcacacagttccttccaaatggct
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
gggcgttttaaagacatctttcaggagatatatgacaagcggtacaagtcccagtttgaa
gcccaaaagatctggtatgagcacaggctcatcgacgacatggtggcccaagctatgaaa
tcagagggaggcttcatctgggcctgtaaaaactatgatggtgacgtgcagtcggactct
gtggcccaagggtatggctctctcggcatgatgaccagtgtgctggtttgtccagatggc
aagacagtagaagcagaggctgcccacgggactgtaacccgtcactaccgcatgtaccag
aaaggacaggagacgtccaccaatcccattgcttccatttttgcctggaccagagggtta
gcccacagagcaaagcttgataacaataaagagcttgccttctttgcaaatgctttggaa
gaagtctctattgagacaattgaggctggcttcatgaccaaggacttggctgcttgcatt
aaaggtttacccaatgtgcaacgttctgactacttgaatacatttgagttcatggataaa
cttggagaaaacttgaagatcaaactagctcaggccaaactttaa
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