Pan troglodytes (chimpanzee): 460447
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Entry
460447 CDS
T01005
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X20
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04010
MAPK signaling pathway
ptr04020
Calcium signaling pathway
ptr04022
cGMP-PKG signaling pathway
ptr04024
cAMP signaling pathway
ptr04218
Cellular senescence
ptr04260
Cardiac muscle contraction
ptr04261
Adrenergic signaling in cardiomyocytes
ptr04270
Vascular smooth muscle contraction
ptr04530
Tight junction
ptr04713
Circadian entrainment
ptr04723
Retrograde endocannabinoid signaling
ptr04724
Glutamatergic synapse
ptr04725
Cholinergic synapse
ptr04726
Serotonergic synapse
ptr04727
GABAergic synapse
ptr04728
Dopaminergic synapse
ptr04911
Insulin secretion
ptr04912
GnRH signaling pathway
ptr04921
Oxytocin signaling pathway
ptr04924
Renin secretion
ptr04925
Aldosterone synthesis and secretion
ptr04927
Cortisol synthesis and secretion
ptr04929
GnRH secretion
ptr04930
Type II diabetes mellitus
ptr04934
Cushing syndrome
ptr04935
Growth hormone synthesis, secretion and action
ptr04973
Carbohydrate digestion and absorption
ptr05010
Alzheimer disease
ptr05020
Prion disease
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05031
Amphetamine addiction
ptr05207
Chemical carcinogenesis - receptor activation
ptr05410
Hypertrophic cardiomyopathy
ptr05412
Arrhythmogenic right ventricular cardiomyopathy
ptr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
460447 (CACNA1D)
04020 Calcium signaling pathway
460447 (CACNA1D)
04024 cAMP signaling pathway
460447 (CACNA1D)
04022 cGMP-PKG signaling pathway
460447 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
460447 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
460447 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
460447 (CACNA1D)
04929 GnRH secretion
460447 (CACNA1D)
04912 GnRH signaling pathway
460447 (CACNA1D)
04921 Oxytocin signaling pathway
460447 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
460447 (CACNA1D)
04924 Renin secretion
460447 (CACNA1D)
04925 Aldosterone synthesis and secretion
460447 (CACNA1D)
04927 Cortisol synthesis and secretion
460447 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
460447 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
460447 (CACNA1D)
04270 Vascular smooth muscle contraction
460447 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
460447 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
460447 (CACNA1D)
04727 GABAergic synapse
460447 (CACNA1D)
04725 Cholinergic synapse
460447 (CACNA1D)
04728 Dopaminergic synapse
460447 (CACNA1D)
04726 Serotonergic synapse
460447 (CACNA1D)
04723 Retrograde endocannabinoid signaling
460447 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
460447 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
460447 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
460447 (CACNA1D)
05020 Prion disease
460447 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
460447 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
460447 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
460447 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
460447 (CACNA1D)
05414 Dilated cardiomyopathy
460447 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
460447 (CACNA1D)
04934 Cushing syndrome
460447 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ptr04040
]
460447 (CACNA1D)
Ion channels [BR:
ptr04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
460447 (CACNA1D)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
NCAPD3_N
Motif
Other DBs
NCBI-GeneID:
460447
NCBI-ProteinID:
XP_016796775
Ensembl:
ENSPTRG00000015026
VGNC:
53362
LinkDB
All DBs
Position
2:57535998..57853823
Genome browser
AA seq
2246 aa
AA seq
DB search
MPGEPLPLWGSPPQLWPGHHVQLPRRPGLGRGRMEQLLASPPLWRPPVPPNPCRLEAFPE
ANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQR
KRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVAL
AIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFV
IVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNS
IIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNG
RQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPW
VYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWIT
QAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVSGEGENRGCCGSLWCWWRRRGAAK
AGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSE
HYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETI
LVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIII
FSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSS
SGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESL
ENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGP
RPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAAL
AAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVV
GVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTT
LLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFN
FDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFM
MNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVN
SSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKG
YFSDAWNTFDSLIVIGSIIDVALSEADHYFTDAWNTFDALIVVGSVVDIAITEVNPTESE
NVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVAL
LIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLAC
LPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWS
ILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMN
MPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPP
AGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIR
RAISCDLQDDEPEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQR
PSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIG
NLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYFR
DPHCLGEQEYFSSEECYEDDSSPTWSRQNYGYYSRYPGRNIDSERPQGYHHPQGFLEDDD
SPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQ
QQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGS
LPSLHRSSWYTDEPDISYRTFTPASLTIPSSFRNKNSDKQRSADSLVEAVLISEGLGRYA
RDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVHPRANGDVGPLSHRQDYELQDFGP
GYSDEEPDPGRDEEDLADEMICITTL
NT seq
6741 nt
NT seq
+upstream
nt +downstream
nt
atgcccggggagccgctgccgctgtggggctcccctccccagctctggcccgggcaccac
gtgcagcttccacgccggccggggctgggtcgagggaggatggagcagctcctggccagc
cctcccctttggagaccgccagtgccccccaacccctgtcggctggaagcctttccggag
gcaaactatgcaagaggcaccagacttcctctttctggtgaaggaccaacttctcagccg
aatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgctagacaggcc
aaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctctcccaaaga
aaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagccgacctgcc
cgcgcccttttctgtttatcactcaataaccccatccgaagagcctgcattagtatagtg
gaatggaaaccatttgacatatttatattattggctatttttgccaattgtgtggcctta
gctatttacatcccattccctgaagatgattctaattcaacaaatcataacttggaaaaa
gtagaatatgccttcctgattatttttacagtcgagacatttttgaagattatagcgtat
ggattattgctacatcctaatgcttatgttaggaatggatggaatttactggattttgtt
atagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaaacagaaggc
gggaaccactcaagcggcaaatctggaggctttgatgtcaaagccctccgtgcctttcga
gtgttgcgaccacttcgactagtgtcaggagtgcccagtttacaagttgtcctgaactcc
attataaaagccatggttcccctccttcacatagcccttttggtattatttgtaatcata
atctatgctattataggattggaactttttattggaaaaatgcacaaaacatgttttttt
gctgactcagatatcgtagctgaagaggacccagctccatgtgcgttctcagggaatgga
cgccagtgtactgccaatggcacggaatgtaggagtggctgggttggcccgaacggaggc
atcaccaactttgataactttgcctttgccatgcttactgtgtttcagtgcatcaccatg
gagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaatggccatgg
gtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctggttcttggt
gtccttagtggagaattctcaaaggaaagagagaaggcaaaagcacggggagatttccag
aagctccgggagaagcagcagctggaggaggatctaaagggctacttggattggatcacc
caagctgaggacatcgatccggagaatgaggaagaaggaggagaggaaggcaaacgaaat
actagcatgcccaccagcgagactgagtctgtgaacacagagaacgtcagcggtgaaggc
gagaaccgaggctgctgtggaagtctctggtgctggtggagacggagaggcgcggccaag
gcggggccctctgggtgtcggcggtggggtcaagccatctcaaaatccaaactcagccga
cgctggcgtcgctggaaccgattcaatcgcagaagatgtagggccgctgtgaagtctgtc
acgttttactggctggttatcgtcctggtgtttctgaacaccttaaccatttcctctgag
cactacaatcagccagattggttgacacagattcaagatattgccaacaaagtcctcttg
gctctgttcacctgcgagatgctggtaaaaatgtacagcttgggcctccaagcatatttc
gtctctcttttcaaccggtttgattgcttcgtggtgtgtggtggaatcactgagacgatc
ttggtggaactggaaatcatgtctcccctggggatctctgtgtttcggtgtgtgcgcctc
ttaagaatcttcaaagtgaccaggcactggacttccctgagcaacttagtggcatcctta
ttaaactccatgaagtccatcgcttcgctgttgcttctgctttttctcttcattatcatc
ttttccttgcttgggatgcagctgtttggcggcaagtttaattttgatgaaacgcaaacc
aagcggagcacctttgacaatttccctcaagcacttctcacagtgttccagatcctgaca
ggcgaagactggaatgctgtgatgtacgatggcatcatggcttacgggggcccgtcctct
tcaggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaactatattcta
ctgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagtctgaacact
gctcagaaggaagaagcggaagaaaaggagaggaaaaagattgccagaaaagagagccta
gaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgacaacaaggtt
acaattgatgactatagagaagaggatgaagacaaggacccctacccgccttgcgatgtg
ccagtaggggaagaggaagaggaagaggaggaggatgaacctgaggttcctgccggaccc
cgtcctcgaaggatctcggagttgaacatgaaggaaaaaattgcccccatccctgaaggg
agcgctttcttcattcttagcaagaccaacccgatccgcgtaggctgccacaagctcatc
aaccaccacatcttcaccaacctcatccttgtcttcatcatgctgagcagcgctgccctg
gccgcagaggaccccatccgcagccactccttccggaacacgatactgggttactttgac
tatgccttcacagccatctttactgttgagatcctgttgaagatgacaacttttggagct
ttcctccacaaaggggccttctgcaggaactacttcaatttgctggatatgctggtggtt
ggggtgtctctggtgtcatttgggattcaatccagtgccatctccgttgtgaagattctg
agggtcttaagggtcctgcgtcccctcagggccatcaacagagcaaaaggacttaagcac
gtggtccagtgcgtcttcgtggccatccggaccatcggcaacatcatgatcgtcaccacc
ctcctccagttcatgtttgcctgtatcggggtccagttgttcaaggggaagttctatcgc
tgtacggatgaagccaaaagtaaccctgaagaatgcaggggacttttcatcctctacaag
gatggggatgttgacagtcctgtggtccgtgagcggatctggcaaaacagtgatttcaac
ttcgacaacgtcctctctgctatgatggcactcttcacggtctccacgtttgagggctgg
cctgcgttgctgtataaagccatcgactcgaatggagagaacatcggcccaatctacaac
caccgtgtggagatctccatcttcttcatcatctacatcatcattgtagctttcttcatg
atgaacatctttgtgggctttgtcatcgttacatttcaggaacaaggagaaaaagagtat
aagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttgaaagcacgt
cccttgcggagatacatccccaaaaacccctaccagtacaagttctggtacgtggtgaac
tcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgcttggcc
atgcagcactacgagcagtccaagatgttcaatgatgccatggacattctgaacatggtc
ttcaccggggtgttcaccgtcgagatggttttgaaagtcatcgcatttaagcctaagggg
tattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagcattatagac
gtggccctcagcgaagcagaccactatttcactgatgcatggaacacttttgatgcctta
attgttgttggtagcgtcgttgatattgctataactgaagtgaatccaactgaaagtgaa
aatgtccctgtcccaactgctacacctgggaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggc
atccggacattgctgtggacttttattaagtcctttcaggcgctcccgtatgtggccctc
ctcatagccatgctgttcttcatctatgcggtcattggcatgcagatgtttgggaaagtt
gccatgagagataacaaccagatcaataggaacaataacttccagacgtttccccaggcg
gtgctgctgctcttcaggtgtgcaacaggtgaggcctggcaggagatcatgctggcctgt
ctcccagggaagctctgtgaccctgagtcagattacaaccccggggaggagtatacatgt
gggagcaactttgccattgtctatttcatcagtttttacatgctctgtgcatttctgatc
atcaatctgtttgtggctgtcatcatggataatttcgactatctgacccgggactggtct
attttggggcctcaccatttagatgaattcaaaagaatatggtcagaatatgaccctgag
gcaaagggaaggataaaacaccttgatgtggtcactctgcttcgacgcatccagcctccc
ctggggtttgggaagttatgtccacacagagtagcgtgcaagagattagttgccatgaac
atgcctctcaacagtgacgggacagtcatgtttaatgcaaccctgtttgctttggttcga
acggctcttaagatcaagaccgaagggaacctggagcaagctaatgaagaacttcgggct
gtgataaagaaaatttggaagaaaaccagcatgaaattacttgaccaagttgtccctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggactggtgggaaagtaccctgcgaagaac
accacaattgccctacaggcgggattaaggacactgcatgacattgggccagaaatccgg
cgtgctatatcgtgtgatttgcaagatgacgagcctgaggaaacaaaacgagaagaagaa
gatgatgtgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagattcccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcg
gtgtgtcataaccatcataaccataattccataggaaagcaagttcccacctcaacaaat
gccaatctcaataatgccaatatgtccaaagctgcccatggaaagcggcccagcattggg
aaccttgagcatgtgtctgaaaatgggcatcattcttcccacaagcatgaccgggagcct
cagagaaggtccagtgtgaaaagaacccgctattatgaaacttacattaggtccgactca
ggagatgaacagctcccaactatttgccgggaagacccagagatacatggctatttcagg
gacccccactgcttgggggagcaggagtatttcagtagtgaggaatgctacgaggacgac
agctcgcccacctggagcaggcaaaactatggctactacagcagatacccaggcagaaac
atcgactctgagaggccccaaggctaccatcacccccaaggattcttggaggacgatgac
tcgcccgtttgctatgattcacggagatctccaaggagacgcctactacctcccacccca
gcatcccaccggagatcctccttcaactttgagtgcctgcgccggcagagcagccaggaa
gaggtcccgtcgtctcccatcttcccccatcgcacggccctgcctctgcatctaatgcag
caacagatcatggcagttgccggcctagattcaagtaaagcccagaagtactcaccgagt
cactcgacccggtcgtgggccacccctccagcaacccctccctaccgggactggacaccg
tgctacacccccctgatccaagtggagcagtcagaggccctggaccaggtgaacggcagc
ctgccgtccctgcaccgcagctcctggtacacagacgagcccgacatctcctaccggact
ttcacaccagccagcctgaccatccccagcagcttccggaacaaaaacagcgacaagcag
aggagtgcggacagcttggtggaggcagtcctgatatccgaaggcttgggacgctatgca
agggacccaaaatttgtgtcagcaacaaaacacgaaatcgctgatgcctgtgacctcacc
atcgacgagatggagagcgcagccagcaccttgcttaatgggaacgtgcatccccgagcc
aacggggatgtgggccccctctcacaccggcaggactatgagctacaggactttggtcct
ggctacagcgacgaagagccagaccctgggagggatgaggaggacctggcggatgaaatg
atatgcatcaccaccttgtag
DBGET
integrated database retrieval system
