KEGG   Pan troglodytes (chimpanzee): 461014
Entry
461014            CDS       T01005                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA isoform X1
  KO
K04513  Ras homolog gene family, member A
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04014  Ras signaling pathway
ptr04015  Rap1 signaling pathway
ptr04022  cGMP-PKG signaling pathway
ptr04024  cAMP signaling pathway
ptr04062  Chemokine signaling pathway
ptr04071  Sphingolipid signaling pathway
ptr04072  Phospholipase D signaling pathway
ptr04081  Hormone signaling
ptr04144  Endocytosis
ptr04150  mTOR signaling pathway
ptr04270  Vascular smooth muscle contraction
ptr04310  Wnt signaling pathway
ptr04350  TGF-beta signaling pathway
ptr04360  Axon guidance
ptr04510  Focal adhesion
ptr04520  Adherens junction
ptr04530  Tight junction
ptr04611  Platelet activation
ptr04621  NOD-like receptor signaling pathway
ptr04625  C-type lectin receptor signaling pathway
ptr04660  T cell receptor signaling pathway
ptr04670  Leukocyte transendothelial migration
ptr04722  Neurotrophin signaling pathway
ptr04810  Regulation of actin cytoskeleton
ptr04921  Oxytocin signaling pathway
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04972  Pancreatic secretion
ptr05100  Bacterial invasion of epithelial cells
ptr05132  Salmonella infection
ptr05133  Pertussis
ptr05135  Yersinia infection
ptr05152  Tuberculosis
ptr05163  Human cytomegalovirus infection
ptr05200  Pathways in cancer
ptr05203  Viral carcinogenesis
ptr05205  Proteoglycans in cancer
ptr05206  MicroRNAs in cancer
ptr05210  Colorectal cancer
ptr05417  Lipid and atherosclerosis
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    461014 (RHOA)
   04015 Rap1 signaling pathway
    461014 (RHOA)
   04310 Wnt signaling pathway
    461014 (RHOA)
   04350 TGF-beta signaling pathway
    461014 (RHOA)
   04072 Phospholipase D signaling pathway
    461014 (RHOA)
   04071 Sphingolipid signaling pathway
    461014 (RHOA)
   04024 cAMP signaling pathway
    461014 (RHOA)
   04022 cGMP-PKG signaling pathway
    461014 (RHOA)
   04150 mTOR signaling pathway
    461014 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    461014 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    461014 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    461014 (RHOA)
   04660 T cell receptor signaling pathway
    461014 (RHOA)
   04670 Leukocyte transendothelial migration
    461014 (RHOA)
   04062 Chemokine signaling pathway
    461014 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    461014 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    461014 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    461014 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    461014 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    461014 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    461014 (RHOA)
   05206 MicroRNAs in cancer
    461014 (RHOA)
   05205 Proteoglycans in cancer
    461014 (RHOA)
   05203 Viral carcinogenesis
    461014 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    461014 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    461014 (RHOA)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    461014 (RHOA)
   05133 Pertussis
    461014 (RHOA)
   05152 Tuberculosis
    461014 (RHOA)
   05100 Bacterial invasion of epithelial cells
    461014 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    461014 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    461014 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ptr04131]
    461014 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ptr04147]
    461014 (RHOA)
   04031 GTP-binding proteins [BR:ptr04031]
    461014 (RHOA)
Membrane trafficking [BR:ptr04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    461014 (RHOA)
Exosome [BR:ptr04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   461014 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   461014 (RHOA)
  Exosomal proteins of colorectal cancer cells
   461014 (RHOA)
  Exosomal proteins of bladder cancer cells
   461014 (RHOA)
GTP-binding proteins [BR:ptr04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    461014 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 461014
NCBI-ProteinID: XP_001163851
Ensembl: ENSPTRG00000014922
VGNC: 12171
UniProt: A0A6D2Y021 H2QML4
LinkDB
Position
2:complement(53390894..53446500)
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggtgatggagcctgtggaaagacatgc
ttgctcatagtcttcagcaaggaccagttcccagaggtgtatgtgcccacagtgtttgag
aactatgtggcagatatcgaggtggatggaaagcaggtagagttggctttgtgggacaca
gctgggcaggaagattatgatcgcctgaggcccctctcctacccagataccgatgttata
ctgatgtgtttttccatcgacagccctgatagtttagaaaacatcccagaaaagtggacc
ccagaagtcaagcatttctgtcccaacgtgcccatcatcctggttgggaataagaaggat
cttcggaatgatgagcacacaaggcgggagctagccaagatgaagcaggagccggtgaaa
cctgaagaaggcagagatatggcaaacaggattggcgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagagaggtttttgaaatggctacgagagctgctctgcaa
gctagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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