Pan troglodytes (chimpanzee): 461206
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Entry
461206 CDS
T01005
Symbol
HPSE
Name
(RefSeq) heparanase
KO
K07964
heparanase [EC:
3.2.1.166
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00531
Glycosaminoglycan degradation
ptr01100
Metabolic pathways
ptr05205
Proteoglycans in cancer
Module
ptr_M00078
Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
461206 (HPSE)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
461206 (HPSE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
ptr00536
]
461206 (HPSE)
Enzymes [BR:
ptr01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.166 heparanase
461206 (HPSE)
Glycosaminoglycan binding proteins [BR:
ptr00536
]
Heparan sulfate / Heparin
Enzymes
461206 (HPSE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_79n
Motif
Other DBs
NCBI-GeneID:
461206
NCBI-ProteinID:
XP_517183
Ensembl:
ENSPTRG00000016229
VGNC:
614
UniProt:
A0A8I3B320
K7BLU7
H2QPT5
LinkDB
All DBs
Position
3:46806841..46846400
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AA seq
592 aa
AA seq
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MEGAVGGVRRRNGAEERRKGRWGSAGGSARALDSPLRGSWRGEQPGEPKMLLRSKPALPP
PLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRF
LIFLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQSQVNQDICKYGS
IPPDVEEKLRLEWPYQEQLLLREHYQKKFKNGTYSRSSVDVLYTFANCSGLDLIFGLNAL
LRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGSQLGEDFIQLHK
LLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYLNGRTATKEDFL
NPDVLDIFISSVQKVFQVVESTRPGQKVWLGETSSAYGGGAPLLSDTFAAGFMWLDKLGL
SARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLMASVKGSKRRKL
RVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFFNKQVDKYLLRPLGPHGLLSK
SVQLNGQTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVAACI
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgcagtgggaggggtgaggaggcgtaacggggcggaggaaaggagaaaaggg
cgctggggctcggcgggaggaagtgctcgagctctcgactctccgctgcgcggcagctgg
cggggagagcagccaggtgagcccaagatgctgctgcgctcgaagcctgcgctgccgccg
ccgctgatgctgctgctcctggggccgctgggtcccctctcccctggcgccctgccccga
cctgcgcaagcacaggacgtcgtggacctggacttcttcacccaggagccgctgcacctg
gtgagcccctcgttcctgtccgtcaccattgacgccaacctggccacggacccgcggttc
ctcatcttcctgggttctccaaagcttcgtaccttggccagaggcttgtctcctgcgtac
ctgaggtttggtggcaccaagacagacttcctaattttcgatcccaagaaggaatcaacc
tttgaagagagaagttactggcaatctcaagtcaaccaggatatttgcaaatatggatcc
atccctcctgatgtggaggagaagttacggttggaatggccctaccaggagcaattgcta
ctccgagaacactaccagaaaaagttcaagaatggcacctactcaagaagctctgtagat
gtgctatacacttttgcaaactgctcaggactggacttgatctttggcctaaatgcgtta
ttaagaacagcagatttgcagtggaacagttctaatgctcagttgctcctggactactgc
tcttccaaggggtataacatttcttgggaactaggcaatgaacctaacagtttccttaag
aaggctgatattttcatcaatgggtcgcagttaggagaagattttattcaattgcataaa
cttctgagaaagtccaccttcaaaaatgcaaaactctatggtcctgatgttggtcagcct
cgaagaaagacggctaagatgctgaagagcttcctgaaggctggtggagaagtgattgat
tcagttacatggcatcactactatttgaatggacggactgctaccaaggaagattttcta
aaccccgacgtattggacatttttatttcatctgtgcaaaaagttttccaggtggttgag
agcaccaggcctggccagaaggtctggttaggagaaacaagctctgcatatggaggcgga
gcgcccttgctatccgacacctttgcagctggctttatgtggctggataaattgggcctg
tcagcccgaatgggaatagaagtggtgatgaggcaagtattctttggagcaggaaactac
catttagtggatgaaaacttcgatcctttacccgattattggctatctcttctgttcaag
aaattggtgggcaccaaggtgttaatggcaagcgtgaaaggttcaaagagaaggaagctt
cgagtataccttcattgcacaaacactgacaatccaaggtataaagaaggagatttaact
ctgtatgccataaacctccataatgtcaccaagtacttgcggttaccctatccttttttt
aacaagcaagtggataaataccttctaagacctttgggacctcatggattactttccaaa
tctgtccaactcaatggtcaaactctaaagatggtggatgatcaaaccttgccaccttta
atggaaaaacctctccggccaggaagttcactgggcttgccagctttctcatatagtttt
tttgtgataagaaatgccaaagttgctgcttgcatctga
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