KEGG   Pan troglodytes (chimpanzee): 461403
Entry
461403            CDS       T01005                                 
Symbol
PPP3CA
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04010  MAPK signaling pathway
ptr04020  Calcium signaling pathway
ptr04022  cGMP-PKG signaling pathway
ptr04114  Oocyte meiosis
ptr04218  Cellular senescence
ptr04310  Wnt signaling pathway
ptr04360  Axon guidance
ptr04370  VEGF signaling pathway
ptr04380  Osteoclast differentiation
ptr04625  C-type lectin receptor signaling pathway
ptr04650  Natural killer cell mediated cytotoxicity
ptr04658  Th1 and Th2 cell differentiation
ptr04659  Th17 cell differentiation
ptr04660  T cell receptor signaling pathway
ptr04662  B cell receptor signaling pathway
ptr04720  Long-term potentiation
ptr04724  Glutamatergic synapse
ptr04728  Dopaminergic synapse
ptr04921  Oxytocin signaling pathway
ptr04922  Glucagon signaling pathway
ptr04924  Renin secretion
ptr05010  Alzheimer disease
ptr05014  Amyotrophic lateral sclerosis
ptr05020  Prion disease
ptr05022  Pathways of neurodegeneration - multiple diseases
ptr05031  Amphetamine addiction
ptr05152  Tuberculosis
ptr05163  Human cytomegalovirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05167  Kaposi sarcoma-associated herpesvirus infection
ptr05170  Human immunodeficiency virus 1 infection
ptr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    461403 (PPP3CA)
   04310 Wnt signaling pathway
    461403 (PPP3CA)
   04370 VEGF signaling pathway
    461403 (PPP3CA)
   04020 Calcium signaling pathway
    461403 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    461403 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    461403 (PPP3CA)
   04218 Cellular senescence
    461403 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    461403 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    461403 (PPP3CA)
   04660 T cell receptor signaling pathway
    461403 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    461403 (PPP3CA)
   04659 Th17 cell differentiation
    461403 (PPP3CA)
   04662 B cell receptor signaling pathway
    461403 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    461403 (PPP3CA)
   04921 Oxytocin signaling pathway
    461403 (PPP3CA)
   04924 Renin secretion
    461403 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    461403 (PPP3CA)
   04728 Dopaminergic synapse
    461403 (PPP3CA)
   04720 Long-term potentiation
    461403 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    461403 (PPP3CA)
   04380 Osteoclast differentiation
    461403 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    461403 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    461403 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    461403 (PPP3CA)
   05163 Human cytomegalovirus infection
    461403 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    461403 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    461403 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    461403 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    461403 (PPP3CA)
   05020 Prion disease
    461403 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    461403 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    461403 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    461403 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ptr01009]
    461403 (PPP3CA)
Enzymes [BR:ptr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     461403 (PPP3CA)
Protein phosphatases and associated proteins [BR:ptr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     461403 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 461403
NCBI-ProteinID: XP_016807409
Ensembl: ENSPTRG00000016315
VGNC: 7727
UniProt: A0A2I3RSP9 A0A6D2X3S7
LinkDB
Position
3:complement(102486403..102809418)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcgcatcttatgaaggagggaaggctggaagagagtgtt
gcattgagaataataacagagggtgcatcaattcttcgacaggaaaaaaatttgctggat
attgatgcgccagtcactgtttgtggggacattcatggacaattctttgatttgatgaag
ctctttgaagtcgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtattgaatgtgtgctgtatttgtgggccttgaaaattctctac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgtatggat
gcctttgactgccttcccctggctgccctgatgaaccaacagttcctgtgtgtacatggt
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcatatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
cacgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtcccttccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaagaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccaactggcatgctccccagcggagtactttctggaggg
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

DBGET integrated database retrieval system