Pan troglodytes (chimpanzee): 463123
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Entry
463123 CDS
T01005
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00230
Purine metabolism
ptr01100
Metabolic pathways
ptr04024
cAMP signaling pathway
ptr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
463123 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
463123 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
463123 (PDE10A)
Enzymes [BR:
ptr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
463123 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
463123 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
463123
NCBI-ProteinID:
XP_016812091
Ensembl:
ENSPTRG00000018787
VGNC:
7902
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Position
5:complement(177415262..177753679)
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AA seq
1076 aa
AA seq
DB search
MASLEEPLAPRPQGPLPAAGDEPGCGPGKLRPEPRLSAAGGGSAAGPGPAPEWPGRGRAE
RAAPPRPPPSSAGRPSPAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSFFYFWP
PPPPPPPSFLPSSSAFHLPVRLPGREGAAAAAAAAGGGGDAGGGGGGGQEAAPLSVPTSS
SHRGGGGSGGGRRRLFLSPALQGLLLPARAGPRPPPPPRLPLGQAARRAGSPGFPGAGPG
GGGQTPRRPQGASFALAAAAALLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKAYL
SLHPQVLDEFVSESVSAETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIE
QRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAG
PITQGTTVSAYVAKSRKTLLVEDILGDERFPGGTGLESGTRIQSVLCLPIVTAIGDLIGI
LELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDN
IVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIR
FSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQ
MVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTS
EEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIM
SVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLENWEYLRALTLTLLRPQTTPLR
KGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFST
LSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTAC
DLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAV
AIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
NT seq
3231 nt
NT seq
+upstream
nt +downstream
nt
atggccagcctcgaggagcctcttgctccccgcccccagggtcccctgccagcggccggg
gacgagccgggctgcggccccggcaaactccgcccggaaccccggctcagcgcggccggc
ggggggagcgcggcgggcccgggcccggcccccgagtggcctggccgtggccgggcggag
cgcgccgcgcccccgcgcccgcccccctcctccgcaggccgccccagccccgctgggggc
cccggcgccctctctgcgcgcggcggcggctgcggctgggtcgcggcccgcgctcccttg
gcgctcgccttctcctcccgggtcccctcctcctctccatctttcttttacttctggccg
ccgccccccccgccccctccctcttttctcccctcctcatctgcctttcacctccccgtg
cgtctcccaggaagggagggcgcagcggcggcggcggcggcggcgggaggaggcggcgat
gctggcggaggaggaggaggaggacaagaggcagctcccttgagcgtccccaccagcagt
agtcaccgcggcggcggtggcagcggcggcgggcggcggcggctcttcctctcgcctgcg
ctccagggcttgctgcttccagcccgtgccggtccccggccgccgccgccgccccggctc
ccccttggccaggccgcccgccgcgcgggctcccccggcttccccggcgccggcccaggc
ggcggcggccaaactccgcggcgtccccagggcgccagcttcgccctcgccgccgcggcc
gcgctgctcttcggctccgacatggaagatggaccttctaataatgcgagctgcttccga
aggctgaccgagtgcttcctgagccccagtttgacagatgaaaaagtgaaggcatatctt
tctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagagacagta
gagaaatggctgaagaggaagaacaacaaatcagaagatgaatcggctcctaaggaagtc
agcaggtaccaagatacgaatatgcagggagttgtatatgaactaaacagctatatagaa
caacggttggacacaggaggagacaaccagctactcctctatgaactgagcagcatcatt
aaaatagccacaaaagccgatggatttgcactgtatttccttggagagtgcaataatagc
ctgtgcatattcacaccacctgggataaaggaaggaaaaccccgcctcatccctgctggg
cccatcactcagggcaccaccgtctctgcttatgtggccaagtccaggaaaacactgcta
gtagaagacatccttggagatgaacgatttccaggaggtactggactggaatcagggact
cgtatccagtctgttctttgcttaccaattgtcactgcaattggtgacttgattggtatt
ctcgagctgtatcggcactggggcaaagaagccttctgtcttagtcaccaggaggttgca
acagcaaatcttgcctgggcttcagtagcaatacatcaggtgcaggtatgcagaggcctt
gccaaacagacagaattgaatgacttcctactcgacgtatcaaaaacatattttgataac
atagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctggtgaat
gccgatcgttgtgcacttttccaggtagaccataagaacaaggagttatattcagacctt
tttgatattggagaggaaaaggaaggaaaacctgtcttcaagaagaccaaagagataaga
ttttcaattgagaaaggaattgctggccaagtagcaagaacaggggaagtcctgaacatt
ccagatgcctatgcagacccacgctttaacagagaagtagacttgtacacaggctacacc
acgcggaacatcctgtgcatgcccatcgtcagccgaggcagcgtgataggtgtggtgcag
atggtcaacaaaatcagtggcagtgccttctctaaaacagatgaaaacaacttcaaaatg
tttgccgtcttttgtgctttagccttacactgtgctaatatgtatcatagaattcgccac
tcagagtgcatttaccgggtaacgatggaaaagctgtcctaccatagcatttgtacttcg
gaagagtggcaaggcctcatgcaattcacccttcccgtgcgtctctgcaaagaaattgag
ttattccactttgacattggtccttttgaaaacatgtggcctggaatttttgtctacatg
gttcatcggtcctgtgggacatcctgctttgagcttgaaaagttgtgtcgttttattatg
tctgtgaagaagaactatcggcgggttccttatcacaactggaagcatgcggtcactgta
gcacactgcatgtatgccatacttcagaacaatcacacgcttttcacagaccttgagaat
tgggagtacttgagagctttgaccttgaccctcctccgacctcaaactacacccttgcgc
aaaggactgctgattgcgtgtctgtgtcatgacctggaccacaggggcttcagtaacagc
tacctgcagaagttcgaccaccctctggccgctctctactccacttccaccatggagcag
caccacttctcccagaccgtgtccatcctccagttggaagggcacaatatcttctctact
ctgagctccagtgaatatgagcaggtgcttgagatcatccgcaaagccatcattgccaca
gaccttgctttatactttggaaacaggaagcagttggaagagatgtaccagaccggatca
ctaaaccttaataatcaatcacatagagaccgtgtaattggtttgatgatgactgcctgt
gacctttgttctgtgacaaaactgtggcccgttacaaaattgacggcaaatgatatatat
gcagaattctgggctgagggtgatgaaatgaagaaattgggaatacagcctattcctatg
atggacagagacaagaaggatgaagtcccccaaggccagcttgggttctacaatgccgtg
gccattccctgctatacaacccttacccagatcctccctcccacggagcctcttctgaaa
gcatgcagggataatctcagtcagtgggagaaggtgattcgaggggaggagactgcaacc
tggatttcatccccatccgtggctcagaaggcagctgcatctgaagattga
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