KEGG   Pan troglodytes (chimpanzee): 464630
Entry
464630            CDS       T01005                                 
Symbol
ABCA1
Name
(RefSeq) phospholipid-transporting ATPase ABCA1 isoform X2
  KO
K05641  ATP-binding cassette, subfamily A (ABC1), member 1
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr02010  ABC transporters
ptr04148  Efferocytosis
ptr04975  Fat digestion and absorption
ptr04979  Cholesterol metabolism
ptr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    464630 (ABCA1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    464630 (ABCA1)
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    464630 (ABCA1)
   04979 Cholesterol metabolism
    464630 (ABCA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    464630 (ABCA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptr02000]
    464630 (ABCA1)
Transporters [BR:ptr02000]
 ABC transporters, eukaryotic type
  ABCA (ABC1) subfamily
   ABCA1, 2, 3, 4, 7, 12, 13 subgroups
    464630 (ABCA1)
SSDB
Motif
Pfam: ABC_tran ABC2_membrane_3 R1_ABCA1 AAA_21 DUF4162 AAA_23
Other DBs
NCBI-GeneID: 464630
NCBI-ProteinID: XP_001138040
Ensembl: ENSPTRG00000021219
VGNC: 4595
UniProt: H2R6H1 A0A6D2X5A8
LinkDB
Position
11:33507496..33654799
AA seq 2261 aa
MACWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYEQHECHFPNKA
MPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIVSRLFSDARRLLLYSQKDT
SMKDMRKVLRTLQQIKKSSSNLKLQDFLVDNETFSGFLYHNLSLPKSTVDKMLRADVILH
KVFLQGYQLHLTSLCNGSKSEEMIHLGDQEVSELCGLPREKLAAAERVLRSNMDVLKPIL
RTLNSTSPLPSKELAEATKTLLHSLGTLAQELFSMRSWSDMRQEVMFLTNVNSSSSSTQI
YQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALFGGNGTEEDAETFYDNSTTPYCNDLMK
NLESSPLSRIIWKALKPLLVGKILYTPDTPATRQVMAEVNKTFQELAVFHDLEGMWEELS
PKIWTFMENSQEMDLVRMLLDSRDNDHFWEQQLDGLDWTAQDIVAFLAKHPEDVQSSNGS
VYTWREAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTG
ITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVV
EQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIV
YEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFV
FLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFAS
LLSPVAFGFGCEYFALFEEQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTW
YIEAVFPGQYGIPRPWYFPCTKSYWFGEESDEKSHPGSSQKRMSEICMEEEPTHLKLGVS
IQNLVKVYRDGMKVAVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYIL
GKDIRSEMSTIRQNLGVCPQHNVLFDVLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVG
LPSSKLKSKTSQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQ
GRTIILSTHHMDEADILGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLS
SCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDI
GHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEESGVDAE
TSDGTLPARRNRRAFGDKQSCLRPFTEDDAADPNDSDVDPESRETDLLSGMDGKGSYQVK
GWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQ
PWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEWTTAP
VPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLPPPQRKQNTADILQDL
TGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNTQALPPSQEVNDAIKQMKK
HLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVINNAILRANLQK
GENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQER
VSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLAL
LLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELFTDNKLNNIN
DILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAVEG
VVFFLITVLIQYRFFIRPRPVNAKLPPLNDEDEDVRRERQRILDGGGQNDILEIKELTKI
YRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKMLTGDTTVTRGDAFLNKNSILSN
IHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGVPEKEVGKVGEWAIRKLGLVKYGEK
YAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTGMDPKARRFLWNCALSVVKEGRSVVLT
SHSMEECEALCTRMAIMVNGRFRCLGSVQHLKNRFGDGYTIVVRIAGSNPDLKPVQDFFG
LAFPGSVLKEKHRNMLQYQLPSSLSSLARIFSILSQSKKRLHIEDYSVSQTTLDQVFVNF
AKDQSDDDHLKDLSLHKNQTVVDVAVLTSFLQDEKVKESYV
NT seq 6786 nt   +upstreamnt  +downstreamnt
atggcttgttggcctcagctgaggttgctgctgtggaagaacctcactttcagaagaaga
caaacatgtcagctgctgctggaagtggcctggcctctatttatcttcctgatcctgatc
tctgttcggctgagctacccaccctatgaacaacatgaatgccattttccaaataaagcc
atgccctctgcaggaacacttccttgggttcaggggattatctgtaatgccaacaacccc
tgtttccgttacccgactcctggggaggctcccggagttgttggaaactttaacaaatcc
attgtgtctcgcctgttctcagatgctcggaggcttcttttatacagccagaaagacacc
agcatgaaggacatgcgcaaagttctgagaacattacagcagatcaagaagtccagctca
aacttgaagcttcaagatttcctagtggacaatgaaaccttctctgggttcctgtatcac
aacctctctctcccaaagtctactgtggacaagatgctgagggctgatgtcattctccac
aaggtatttttgcaaggctaccagttacatttgacaagtctgtgcaatggatcaaaatca
gaagagatgattcaccttggtgaccaagaagtttctgagctttgtggcctaccaagggag
aaactggctgcagcagagcgagtacttcgttccaacatggacgtcctgaagccaatcctg
agaacactaaactctacatctcccctcccgagcaaggagctggctgaagccacaaaaaca
ttgctgcatagtcttgggactctggcccaggagctgttcagcatgagaagctggagtgac
atgcgacaggaggtgatgtttctgaccaatgtgaacagctccagctcctccacccaaatc
taccaggctgtgtctcgtattgtctgcgggcatcccgagggaggggggctgaagatcaag
tctctcaactggtatgaggacaacaactacaaagccctctttggaggcaatggcactgag
gaagatgctgaaaccttctatgacaactctacaactccttactgtaatgatttgatgaag
aatttggagtctagtcctctttcccgcattatctggaaagctctgaagccgctgctcgtt
gggaagatcctgtatacacctgacactccagccacaaggcaggtcatggctgaggtgaac
aagaccttccaggaactggctgtgttccatgatctggaaggcatgtgggaggaactcagc
cccaagatctggaccttcatggagaacagccaagaaatggaccttgtccggatgctgttg
gacagcagggacaatgaccacttttgggaacagcagttggatggcttagattggacagcc
caagacatcgtggcgtttttggccaagcacccagaggatgtccagtccagtaatggttct
gtgtacacctggagagaagctttcaacgagactaaccaggcaatccggaccatatctcgc
ttcatggagtgtgtcaacctgaacaagctagaacccatagcaacagaagtctggctcatc
aacaagtccatggagctgctggatgagaggaagttctgggctggtattgtgttcactgga
attactccaggcagcattgagctgccccatcatgtcaagtacaagatccgaatggacatt
gacaatgtggagaggacaaataaaatcaaggatgggtactgggaccctggtcctcgagct
gacccctttgaggacatgcggtacgtctgggggggcttcgcctacttgcaggatgtggtg
gagcaggcaatcatcagggtgctgacgggcaccgagaagaaaactggtgtctatatgcaa
cagatgccctatccctgttacgttgatgacatctttctgcgggtgatgagccggtcaatg
cccctcttcatgacgctggcctggatttactcagtggctgtgatcatcaagggcatcgtg
tatgagaaggaggcacggctgaaagagaccatgcggatcatgggcctggacaacagcatc
ctctggtttagctggttcattagtagcctcattcctcttcttgtgagcgctggcctgctg
gtggtcatcctgaagttaggaaacctgctgccctacagtgatcccagcgtggtgtttgtc
ttcctgtccgtgtttgctgtggtgacaatcctgcagtgcttcctgattagcacactcttc
tccagagccaacctggcagcagcctgtgggggcatcatctacttcacgctgtacctaccc
tacgtcctgtgtgtggcatggcaggactacgtgggcttcacactcaagatcttcgctagc
ctgctgtctcctgtggcttttgggtttggctgtgagtactttgccctttttgaggagcag
ggcattggagtgcagtgggacaacctgtttgagagtcctgtggaggaagatggcttcaat
ctcaccacttcggtctccatgatgctgtttgacaccttcctctatggggtgatgacctgg
tacattgaggctgtctttccaggccagtacggaattcccaggccctggtattttccttgc
accaagtcctactggtttggtgaggaaagtgatgagaagagccaccctggttccagccaa
aagagaatgtcagaaatctgcatggaggaggaacccacccacctgaagctgggcgtgtcc
attcagaacctggtaaaagtctaccgagatgggatgaaggtggctgtcgatggcctggca
ctgaatttttatgagggccagatcacctccttcctgggccacaatggagcggggaagacg
accaccatgtcaatcctgaccgggttgttccccccgacctcgggcaccgcctacatcctg
ggaaaagacattcgctctgagatgagcaccatccggcagaacctgggggtctgtccccag
cataacgtgctgtttgacgtgctgactgtcgaagaacacatctggttctatgcccgcttg
aaagggctctctgagaagcacgtgaaggcggagatggagcagatggccctggatgttggt
ttgccatcaagcaagctgaaaagcaaaacaagccagctgtcaggtggaatgcagagaaag
ctatctgtggccttggcctttgtcgggggatctaaggttgtcattctggatgaacccaca
gctggtgtggacccttactcccgcaggggaatatgggagctgctgctgaaataccgacaa
ggccgcaccattattctctctacacaccacatggatgaagcggacatcctgggggacagg
attgccatcatctcccatgggaagctgtgctgtgtgggctcctccctgtttctgaagaac
cagctgggaacaggctactacctgaccctggtcaagaaagatgtggaatcctccctcagt
tcctgcagaaacagtagtagcactgtgtcatacctgaaaaaggaggacagtgtttctcag
agcagttctgatgctggcctgggcagcgaccatgagagtgacacgctgaccatcgatgtc
tctgctatctccaacctcatcaggaagcatgtgtctgaagcccggctggtggaagacata
gggcatgagctgacctatgtgctgccatatgaagctgctaaggagggggcctttgtggaa
ctctttcatgagattgatgaccggctctcagacctgggcatttctagttatggcatctca
gagacgaccctggaagaaatattcctcaaggtggccgaagagagtggggtggatgctgag
acctcagatggtaccttgccagcaagacgaaacaggcgggccttcggggacaagcagagc
tgtcttcgcccgttcactgaagatgatgctgctgatccaaatgattctgacgtagaccca
gaatccagagagacagacttgctcagtgggatggatggcaaagggtcctaccaggtgaaa
ggctggaaacttacacagcaacagtttgtggcccttttgtggaagagactgctaattgcc
agacggagtcggaaaggattttttgctcagattgtcttgccagctgtgtttgtctgcatt
gcccttgtgttcagcctgatcgtgccaccctttggcaagtaccccagcctggaacttcag
ccctggatgtacaacgaacagtacacatttgtcagcaatgatgctcctgaggacacagga
accctggaactcttaaacgccctcacgaaagaccctggcttcgggacccgctgtatggaa
ggaaacccaatcccagacacgccctgccaggcaggggaggaagagtggaccactgcccca
gttccccagaccatcatggacctcttccagaatgggaactggacaatgcagaacccttca
cctgcatgccagtgtagcagcgacaaaatcaagaagatgctgcctgtgtgtcccccaggg
gcaggggggctgcctcctccacaaagaaaacaaaacactgcagatatccttcaggacctg
acgggaagaaacatttcggattatctggtgaagacatatgtgcagatcatagccaaaagc
ttaaagaacaagatctgggtgaatgagtttaggtatggcggcttttccctgggtgtcagt
aatactcaagcacttcctccgagtcaagaagttaatgatgccatcaaacaaatgaagaaa
cacctaaagctggccaaggacagttctgcagatcgatttctcaacagcttgggaagattt
atgacaggactggacaccaaaaataatgtcaaggtgtggttcaataacaagggctggcat
gcaatcagctctttcctgaatgtcatcaacaatgccattctccgggctaacctgcaaaag
ggagagaaccctagccattatggaattactgctttcaatcatcccctgaatctcaccaag
cagcagctctcagaggtggctctgatgaccacatcagtggatgtccttgtgtccatctgt
gtcatctttgcaatgtccttcgtcccagccagctttgtcgtattcctgatccaggagcgg
gtcagcaaagcaaaacacctgcagttcatcagtggagtgaagcctgtcatctactggctc
tctaattttgtctgggatatgtgcaattacgttgtccctgccacactggtcattatcatc
ttcatctgcttccagcagaagtcctatgtgtcctccaccaatctgcctgtgctagccctt
ctacttttgctgtatgggtggtcaatcacacctctcatgtacccagcctcctttgtgttc
aagatccccagcacagcctatgtcgtgctcaccagcgtgaacctcttcattggcattaat
ggcagcgtggccacctttgtgctggagctgttcaccgacaataagctgaataatatcaat
gatatcctgaagtctgtgttcttgatcttcccacatttttgcctgggacgagggctcatc
gacatggtgaaaaaccaggcaatggctgatgctctggaaaggtttggggagaatcgcttt
gtgtcaccattatcttgggacttggtgggacgaaacctcttcgccatggccgtggaaggg
gtggtgttcttcctcattactgttctgatccagtacagattcttcatcaggcccagacct
gtaaatgcaaagctacctcctctgaatgatgaagatgaagatgtgaggcgggaaagacag
agaattcttgatggtggaggccagaatgatatcttagaaatcaaggagttgacgaagata
tatagaaggaagcggaagcctgctgttgacaggatttgcgtgggcattcctcctggtgag
tgctttgggctcctgggagttaatggggctggaaaatcatcaactttcaagatgttaaca
ggagataccactgttaccagaggagatgctttccttaacaaaaatagtatcttatcaaac
atccatgaagtacatcagaacatgggctactgccctcagtttgatgccatcacagagctg
ttgactgggagagaacacgtggagttctttgcccttttgagaggagtcccagagaaagaa
gttggcaaggttggtgagtgggcgattcggaaactgggcctcgtgaagtatggagaaaaa
tatgctggtaactatagtggaggcaacaaacgcaagctctctacagccatggctttgatc
ggcgggcctcctgtggtgtttctggatgaacccaccacaggcatggatcccaaagcccgg
cggttcttgtggaattgtgccctaagtgttgtcaaggaggggagatcagtagtgcttaca
tctcatagtatggaagaatgtgaagctctttgcactaggatggcaatcatggtcaatgga
aggttcaggtgccttggcagtgtccagcatctaaaaaataggtttggagatggttataca
atagttgtacgaatagcagggtccaacccggacctgaagcctgtccaggatttctttgga
cttgcatttcctggaagtgttctaaaagagaaacaccggaacatgctacaataccagctt
ccatcttcattatcttctctggccaggatattcagcatcctctcccagagcaaaaagcga
ctccacatagaagactactctgtttctcagacaacacttgaccaagtatttgtgaacttt
gccaaggaccaaagtgatgatgaccacttaaaggacctctcattacacaaaaaccagaca
gtagtggacgttgcagttctcacatcttttctacaggatgagaaagtgaaagaaagctat
gtatga

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