Pan troglodytes (chimpanzee): 464815
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Entry
464815 CDS
T01005
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
464815 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
ptr03021
]
464815 (SETX)
Enzymes [BR:
ptr01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
464815 (SETX)
5.6.2.5 RNA 5'-3' helicase
464815 (SETX)
Transcription machinery [BR:
ptr03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
464815 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
SLFN-g3_helicase
Helicase_RecD
AAA_16
nSTAND3
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
464815
NCBI-ProteinID:
XP_016817414
Ensembl:
ENSPTRG00000021495
VGNC:
4861
LinkDB
All DBs
Position
11:6103321..6199267
Genome browser
AA seq
2697 aa
AA seq
DB search
MSTCCWCTPGGASTIDFLKRYASNTLSGEFQTANEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDDLYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRL
GSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIR
SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAP
PCNTFVDLTSACKISPASYNKEESEQMGKTSRKDTHCLEASSPTFSKEPMKVQDSVLIKA
DNTIEGDNNEQNYMKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISS
YTPKDCTSRNGPERGCDRGIIVSTCLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT
KVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHN
LSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELDIFSSHENNCKIQEFHVEDKELIPFT
EMTNTSEKKSSPFKDLMTVPESRDEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRD
LHKLSLLAQASVIMFPSDSPQNSSQLQRKVKEDKRCFTANQSNVGDTSRGQVIIISDSDD
DDDERILSLEKLTKQDKICLERERPEQHVSTVNSKEEKNLVKEEKTETLFQFEESDSQCF
EFESLSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEEH
TRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRGLVGNDFKSI
DRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYLS
CRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVVD
TRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRQRLSDCGSTDVKRAGSHTA
QNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLNQ
CDSVVLNGTIPTNEVIVSTSEDPLGGGDPTARHVEMAALKEGEPDSSSDAEEDNLFLTQN
DTEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKNQ
GEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSALS
PSLKNKSKGIQSILKVPQPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESKYSPSSSPVN
ILFSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHSYGDYFNIFFP
LMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELAKQLYPKEND
LVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKAECYLSIQTQENFPA
NLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPVDFCTKDLLTTTSERIIA
YLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGH
SDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPE
KSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDCQLDELSRQRALCRGGREIQK
QELDENISKVSKERQQLASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRG
QGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSM
MARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCS
SDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKKKDVSFRNIGIITHYK
AQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSMQGSIGFLASLQRLN
VTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWALKENQHWNQLIQD
AQKRGAIIKTCEKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFA
KTSVAASPYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQP
SSPQHPGATPPTGEPGFPVVHQDLSHVQQPAAVVAALSSHKPPLRGEPPAASPEASTCQS
KCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL
NT seq
8094 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggtgcttccaccattgacttcctaaagcgc
tatgcttccaacactctgtccggtgaatttcaaacagccaacgaagacctctgctactgc
ttggagtgtgtggctgagtaccacaaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaatcactttgaaaaatccatgaaggcagaa
attggagatgatgatgatttatatatagtagacaacaatggagagatgccactgtttgac
atcactgggcaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttacttgcttctacatgaacgtgttaacgagttatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgtttgacaaacatccagggatctatttgttttta
gtccatcccaatgaaatggttcggcgttgggctatcttgactgcaagaaacttggggaaa
gtggacagagatgattattatgacttacaggaagttttactttgcctttttaaagtcatt
gagttggggcttttagagagtccagacatttatacttcttctgtcctagagaagggtaaa
ctgattcttctgccctcacacatgtatgatactaccaactacaaaagctattggttaggt
atttgcatgttgctgaccattcttgaggaacaagccatggattccctgttgttgggctca
gacaaacaaaatgattttatgcaatcgatacttcacactatggagagggaagcagatgat
gatagcgtggatcctttctggccagcgttacactgttttatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttatggatcctattgtggcatttcaaaccattatcaac
aacgcaagctacaatagagagatccgacatatacggaacagctctgtaaggaccaagtta
gaaccggagtcctatttggatgatatggtgacttgcagccagatcgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagaacagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagtgtacttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttctatggttcatcccttttgtccagtccctcatggat
cttaaggatttgggtgtggcttacatagcacaggttgttaatcatctgtactctgaagtc
aaagaagtcctcaaccaaacagatgctgtgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcatagaaataaaaaatgtttgcatttgctgtgggta
agttcccagcaatgggtggaagccgtcgtcaaatgtgccaagcttcctaccactgcgttt
acacggagttctgagaaatcatctggaaattgctccaaaggaacagcaatgatatcttca
ctgtcgttgcattccatgccatctaactctgtacaacttgcttatgtgcagctgattaga
agtctccttaaagaaggttatcagcttgggcagcagtctctttgcaagcgattctgggat
aagctcaacttattccttagaggaaatttatctctaggttggcagttgactagtcaggaa
acccatgagctacaaagttgcttaaagcaaattattagaaacataaaattcaaagcacct
ccatgtaacacttttgtggatctgacttctgcatgtaaaatctctcctgcatcttataat
aaagaagaaagtgaacaaatggggaagacgtctagaaaagatacgcattgtttggaagct
tccagcccaacattttctaaagaaccaatgaaagtgcaagacagtgtattgatcaaagca
gataacactatagaaggtgacaataatgagcaaaattatatgaaggatgtgaaactagaa
gaccatctcttagctgggtcatgcttaaagcagagtagtaaaaacatttttactgaaaga
gctgaagatcaaattaaaataagtacaaggaagcagaagtctgtaaaagagatctcttca
tatacaccaaaggattgtacttcaagaaatggtccagaaaggggatgtgacagaggaata
atagtatcaacatgtttgttgactgattctagcactgatgctttggagaaagtgtccaca
tcaaatgaagatttctctttaaaggatgatgctcttgctaaaacctcaaaacgaaaaact
aaggtacagaaagatgaaatctgtgcaaagttatcacatgtaataaagaagcaacacagg
aagagtactttggtcgataatactatcaatttagatgaaaatttgactgtatctaacatt
gagagtttctattcaaggaaagatacaggagttcagaaaggagatggtttcatacacaat
ctttctttagaccctagtggtgttctggatgataagaatggagaacaaaaatctcaaaac
aatgtattgccaaaagagaaacaattaaagaatgaagaattagatattttctcttcccat
gaaaacaattgtaaaatacaggaatttcatgttgaagataaagaattgatcccttttaca
gaaatgaccaatacttctgagaagaaatcatctccctttaaagatcttatgactgtacct
gaatcaagagatgagatgagtaatagtaccagtgtgatttattccaacttgacaagagaa
caggcccctgacatcagtcctaaatcggacaccttaacggattctcagatagacagagac
cttcacaaattatctttactagctcaagccagtgttattatgttcccatccgattcacct
cagaactcatcgcagctgcaaaggaaagtaaaagaagataaaagatgtttcacagctaac
caaagtaatgttggagatacctcccgtggacaggttattattatttcagattctgatgat
gatgatgatgaaagaatcctgagtcttgagaaactcactaaacaggacaaaatatgcctt
gagagggaacgtccagagcagcacgtttcaacagttaatagtaaggaggaaaagaatcta
gtaaaggaagaaaagacagagactctttttcagtttgaggaatctgattctcagtgtttt
gagtttgaaagtttatctgaagtgttttcagtttggcaagatcatccagacgataataat
tcagttcaagatggtgagaaaaaatgtttggctcctatagccaataccacaaatggtcag
ggttgtacagattatgtatctgaagttgttaaaaaaggagcagagggcattgaagaacac
acaagaccacggagtatttctgttgaagaattttgtgaaattgaagttaaaaagcctaag
agaaaacgatctgaaaaaccaatggctgaagatcctgtgaggccttcatcttctgtcaga
aatgagggccagtctgatactaataagagaggtcttgtgggaaatgattttaaaagtata
gatagaaggacttcaactcccaattcacgtattcagagagccactacggtttcacaaaag
aagtcttcaaagctttgtacttgtacagaacccatcaggaaagttccagtttctaagacc
cctaagaaaactcattcagatgccaaaaaaggacagaatagaagttcaaattacctaagt
tgtagaacaactcctgctatagtgccgccaaagaaatttcgtcagtgtcctgagccaact
tcaacagctgagaaacttggcctgaaaaagggtcctcgtaaggcatatgagttgtcccag
cggtctttggattatgtagctcaattacgtgatcatggcaaaactgttggagtagttgat
acccgaaaaaagactaaattaatttctcctcagaacctgtctgtcagaaataataagaaa
cttctgactagtcaagaacttcagatgcaaaggcagatcagacccaaatcacaaaaaaat
agacaaagactttctgattgtggaagtacagatgttaaaagagcagggtcacatacagca
cagaattctgacatatttgtaccagaatctgataggtcagattataattgtacaggagga
actgaggtactcgccaacagtaacagaaaacagttaataaaatgcatgccttctgaacca
gaaaccataaaagcaaaacatgggtctccagcaactgatgatgcttgccctttgaaccag
tgtgattctgtagtgttaaatggaacaataccaacaaatgaagtaattgtctctacttca
gaggaccctctgggtggaggtgatccaacagcacgtcatgtagagatggcagctttgaaa
gagggagagcctgactccagcagtgatgcagaggaagataacttatttttaacccaaaat
gatactgaagatatggatttatgttcacaaatggagaatgacaattataaactcattgaa
ctaattcatggaaaagatacagttgaggttgaagaagattctgtaagtcggcctcagttg
gaatctttgagtggcacaaagtgtaagtacaaagattgtcttgaaaccacaaaaaaccag
ggtgaatactgcccaaaacactctgaagtgaaagcagcagatgaagatgtatttcgtaaa
cctggcttgcctcctcctgcatctaaacctttgagacctaccactaagatttttagctca
aagagtacttcacgaattgctggtctttctaaatctttggaaacttcttcagcactttca
ccgtctctaaaaaataagtcaaaggggatacagtcgattttgaaagtaccacagccagtt
ggtgaaatgaagaattcgtgcaatgttcttcatcctcagtctccgaataattccaacagg
caaggttgcaaagttccatttggtgaaagcaaatattctccatcttcctctccagtaaac
attcttttttcatcacagtctgtctctgacaccttcgttaaagaggtcttaaaatggaaa
tatgaaatgtttttgaactttggtcagtgtgggccccctgcaagtctttgtcagtccatc
tcaagacctgtgcctgtcagatttcacagttatggagattattttaatatttttttccct
ttgatggtattgaatacttttgaaacagtggcacaggaatggctcaactctccaaataga
gagaatttctatcagttgcaagtacgaaaatttcctgccgattatataaaatactgggag
tttgcagtttatctggaagaatgtgaactggctaaacagctttatccaaaggaaaacgat
ttggtgtttttagctcctgagagaataaatgaagagaagaaagatacagagagaaatgac
atacaagatctccatgaatatcattctggttatgttcataaatttcgccgcacttcagtc
atgcgtaatgggaaagctgagtgttacctttccatccagactcaagagaactttccggcc
aatttaaacgaacttgtgaattgtattgtaatcagttctctggtaactacacaaaggaag
ttgaaagccatgtctctgttgggtagtcggaaccaactggctagagctgttctgaatcca
aaccctgtggacttctgtacaaaagatttactgactacaacatctgagagaattattgcg
tacttaagagatttcaatgaagaccaaaagaaagcaatagaaactgcatatgctatggtg
aaacactcaccatcagttgccaaaatctgcttgattcatggaccacctggaacaggaaaa
tcaaaaactattgttggcctcctctatcgtctactgacagagaaccagaggaaggggcat
tcagacgaaaactccaatgccaaaatcaaacaaaaccgtgtcctcgtgtgtgcaccttcc
aatgcagctgttgatgaactcatgaaaaaaattatccttgaattcaaagaaaaatgtaaa
gacaagaagaatcctttaggaaactgtggagatataaatttagtacgactgggtccagaa
aagtctattaatagtgaggttctaaagttcagtttggacagccaagtaaaccacagaatg
aaaaaagagttaccttctcatgttcaggcgatgcataaaagaaaggaatttctagattgt
cagctggatgagctttcccggcagcgagctctatgccgaggtggacgggaaatacagaag
caagaattagatgaaaacatttccaaagtttctaaggaaaggcagcaacttgcttctaaa
attaaagaggttcaaggacgcccacagaaaacacagagtatcatcatcttagagtcccat
atcatctgctgcacgttgagcacaagtggtggtttactacttgagtctgctttccgtggg
caagggggtgtccccttcagctgtgtcattgttgatgaggctggacagtcttgtgaaatt
gagactcttactccactcatccatcgctgcaataagctcatcctagtaggagatcctaag
cagctccctcccacagtcatctctatgaaagcacaggagtatggctacgaccagtcaatg
atggctcgcttctgcagactgctggaagagaatgtagaacacaacatgatcagcaggctg
cccattctacagctcactgttcagtacaggatgcatccagacatatgcctcttcccttct
aattatgtttataacagaaacttaaaaacaaatagacagacagaagccattcgatgttca
tcagactggccatttcagccataccttgtgtttgatgttggagatggttcagaaagacgg
gataatgactcatatataaatgttcaagaaataaaactggtgatggaaataattaagctt
attaaagacaaaaaaaaggatgttagttttcgaaacattggcataataactcattacaag
gcccagaagacgatgattcagaaggatttggacaaagagttcgatagaaaaggaccagca
gaagtagacactgtggatgcattccagggtcggcagaaggattgtgttattgttacgtgt
gtcagagcaaatagcatgcaaggttcaattggattcctggcaagtttgcagagattgaat
gtcaccatcacacgagccaagtacagcctcttcatcctcggacatttgaggaccctgatg
caacttcttcctaggagcttttgtgtacacgtgaaccattcgccttttttcagcccagaa
cccaagtatctacactgggctctcaaggaaaaccagcattggaatcagctgattcaggat
gctcagaagcgtggtgccattattaagacctgtgagaaaaactatagacatgatgcagtg
aagattctgaaactcaagcctgtgctgcagagaagtctcactcaccctcctaccatagcc
ccagaggggtccagaccccagggtggtttgcccagcagcaagctagacagtggatttgcc
aagacatctgttgctgcttctccataccacacaccctctgactccaaggaaattactctt
actgttacttcaaaggaccctgaaagacctcctgttcatgaccaacttcaggacccacga
ctgctgaagaggatgggcattgaggtcaaaggaggaatattcctttgggatccacaaccc
tcgagcccccagcatcctggagcaacacctcctacgggcgagccgggcttccctgtcgtt
caccaggacctgagccatgtacagcagcccgctgctgtagtggctgctctgagcagccac
aaacctcccttgcggggcgaacctccagctgccagtcccgaggcttccacgtgtcagagc
aaatgtgatgacccggaagaggagctctgtcacaggagagaggccagggctttcagtgag
ggggagcaggaaaagtgtggctccgagacccatcacaccaggaggaactctaggtgggac
aagaggacactggagcaggaggacagcagttccaagaaaagaaagcttttatag
DBGET
integrated database retrieval system
