Pan troglodytes (chimpanzee): 465094
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Entry
465094 CDS
T01005
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00520
Amino sugar and nucleotide sugar metabolism
ptr00541
Biosynthesis of various nucleotide sugars
ptr01100
Metabolic pathways
ptr01250
Biosynthesis of nucleotide sugars
Module
ptr_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
465094 (GNE)
00541 Biosynthesis of various nucleotide sugars
465094 (GNE)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
465094 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
465094 (GNE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
Peptidase_M9
Glucokinase
Motif
Other DBs
NCBI-GeneID:
465094
NCBI-ProteinID:
XP_003312121
Ensembl:
ENSPTRG00000020931
VGNC:
8890
UniProt:
A0A6D2WVL4
A0A2I3S7G3
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All DBs
Position
11:79709988..79772212
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AA seq
753 aa
AA seq
DB search
METYGYPQRESCFQGPHELYFKNLSKRNKQIMEKNGNNRKLRVCVATCNRADYSKLAPIM
FGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG
LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA
ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDV
KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG
IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE
NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF
PPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI
LQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH
LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH
LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQ
AAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALS
SVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atggaaacctatggttatccgcagagggagtcatgctttcaaggacctcatgaactctat
tttaagaacctctcaaaacgaaacaagcaaatcatggagaagaatggaaataaccgaaag
ctgcgggtttgtgttgctacttgtaaccgtgcagattattctaaacttgccccgatcatg
tttggcattaaaaccgaacctgagttctttgaacttgatgttgtggtacttggctctcac
ctgatagatgactatggaaatacatatcgaatgattgaacaagatgactttgacattaac
accaggctacacacaattgtgaggggagaagatgaggcagccatggtggagtcagtaggc
ctggccctagtgaagctgccagatgtccttaatcgcctgaagcctgatatcatgattgtt
catggagacaggtttgatgccctggctctggccacatctgctgccttgatgaacatccga
atccttcacattgaaggtggggaagtcagtgggaccattgatgactctatcagacatgcc
ataacaaaactggctcattatcatgtgtgctgcacccgcagtgcagagcagcacctgata
tccatgtgtgaggaccatgatcgcatccttttggcaggctgcccttcctatgacaaactt
ctctcagccaagaacaaagactacatgagcatcattcgcatgtggctaggtgatgatgta
aaatctaaagattacattgttgcactacagcaccctgtgaccactgacattaagcattcc
ataaaaatgtttgaattaacattggatgcacttatctcatttaacaagcggaccctagtc
ctgtttccaaatattgatgcagggagcaaagagatggttcgagtgatgcggaagaagggc
attgagcatcatcccaactttcgtgcagttaaacacgtcccatttgaccagtttatacag
ttggttgcccatgctggctgtatgattgggaacagcagctgtggggttcgagaagttgga
gcttttggaacacctgtgatcaacctgggaacacgtcagattggaagagaaacaggggag
aatgttcttcatgtccgggatgctgacacccaggacaaaatattgcaagcactgcacctt
cagtttggtaaacagtacccttgttcaaagatatatggggatggaaatgctgttccaagg
attttgaagtttctcaaatctatcgatcttcaagagccactgcaaaagaaattctgcttt
cctcctgtgaaggagaatatctctcaagatattgaccatattcttgaaactctaagtgcc
ttggccgttgatctcggcgggacgaacctccgagttgcaatagtcagcatgaagggtgaa
atagttaagaagtatactcagttcaatcctaaaacctatgaagagaggattaatttaatc
ctacagatgtgtgtggaagctgcagcagaagctgtaaaactgaactgcagaattttggga
gtaggcatttccacaggtggccgtgtaaatcctcgggaaggaattgtgctgcattcaacc
aaactgatccaagagtggaactctgtggaccttaggacccccctttctgacactttgcat
ctccctgtgtgggtagacaatgatggcaactgtgctgccctggcggaaaggaaatttggc
caaggaaagggactggaaaactttgttacacttatcacaggcacaggaatcggtggtgga
attatccatcagcatgaattgatccacggaagctccttctgtgctgcagaactgggccac
cttgttgtgtctctggatgggcctgattgttcctgtggaagccatgggtgcattgaagca
tacgcctctggaatggccttgcagagggaggcaaaaaagctccatgatgaggacctgctc
ttggtggaagggatgtcagtgccaaaagatgaggccgtgggtgcgctccatctcatccaa
gctgcgaaacttggcaatgcgaaggcccagagcatcctaagaacagctggaacagctttg
ggtcttggggttgtgaacatcctccataccatgaatccctcccttgtgatcctctccgga
gtcctggccagtcactatatccacattgtcaaagacgtcattcgccagcaggccttgtcc
tccgtgcaggacgtggatgtggtggtttcggatttggttgaccccgccctgctgggtgct
gccagcatggttctggactacacaacacgcaggatctactag
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