Pan troglodytes (chimpanzee): 468086 Help Entry 468086            CDS       T01005                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr04072   Phospholipase D signaling pathway ptr04115   p53 signaling pathway ptr04140   Autophagy - animal ptr04150   mTOR signaling pathway ptr04151   PI3K-Akt signaling pathway ptr04152   AMPK signaling pathway ptr04211   Longevity regulating pathway ptr04218   Cellular senescence ptr04714   Thermogenesis ptr04910   Insulin signaling pathway ptr04919   Thyroid hormone signaling pathway ptr05163   Human cytomegalovirus infection ptr05165   Human papillomavirus infection ptr05168   Herpes simplex virus 1 infection ptr05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ptr00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     468086 (TSC2)    04151 PI3K-Akt signaling pathway     468086 (TSC2)    04152 AMPK signaling pathway     468086 (TSC2)    04150 mTOR signaling pathway     468086 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     468086 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     468086 (TSC2)    04218 Cellular senescence     468086 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     468086 (TSC2)    04919 Thyroid hormone signaling pathway     468086 (TSC2)   09149 Aging    04211 Longevity regulating pathway     468086 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     468086 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     468086 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     468086 (TSC2)    05163 Human cytomegalovirus infection     468086 (TSC2)    05165 Human papillomavirus infection     468086 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:ptr01009]     468086 (TSC2) Protein phosphatases and associated proteins [BR:ptr01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      468086 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  468086 NCBI-ProteinID:  XP_024205801 Ensembl:  ENSPTRG00000031311 VGNC:  48997 LinkDB All DBs Position 18:complement(4373249..4412950) Genome browser AA seq 1807 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDI LLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS GPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG ALDVPASQFLGSATSPGPRTAPAVKPEKASAGTRVPMQEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST AKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGIPGEVPVPVAPPGLEDV EAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERAVSSEGGRPSVDLSFQPSQ PLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQ PEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFV FLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELA ILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFH IATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYEC NLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKW IARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHTKAPAQTPAEPTPGYEVGQRKRLISSV EDFTEFV NT seq 5424 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccaacaagcaaagattcaggcttgaaggagaagtttaagattctgttggga ctgggaacaccgaggccaaatcccaggtctgcagagggtaaacagacggagtttatcatc accgcggaaatactgagagaactgagcatggaatgtggcctcaacaatcgcatccggatg atagggcagatttgtgaagtcgcaaaaaccaagaaatttgaagagcacgcagtggaagca ctctggaaggcggtcgcggatctgttgcagccggagcggccgctggaggcccggcacgcg gtgctggctctgctgaaggccatcgtgcaggggcagggcgagcgtttgggggtcctcaga gccctcttctttaaggtcatcaaggattacccttccaacgaagaccttcacgaaaggctg gaggttttcaaggccctcacagacaatgggagacacatcacctacttggaggaagagctg gctgactttgtcctgcagtggatggatgttggcttgtcctcggaattccttctggtgctg gtgaacttggtcaaattcaatagctgttacctggacgagtacatcgcaaggatggttcag atgatctgtctgctgtgcgtccggactgcgtcctctgtggacatagaggtctccctgcag gtgctggacgccgtggtctgctacaactgcctgccggctgagagcctcccgctgttcatc gttaccctctgtcgcaccatcaacgtcaaggagctctgcgagccttgctggaagctgatg cggaacctccttggcacccacctgggccacagcgccatctacaacatgtgccacctcatg gaggacagagcctacatggaggacgcgcccctgctgagaggagctgtgttttttgtgggc atggctctctggggagcccaccggctctattctctcaggaactcgccgacatctgtgttg ccatcattttaccaggccatggcatgtccgaacgaggtggtgtcctatgagatcgtcctg tccatcaccaggctcatcaagaagtataggaaggagctccaggtggtggcgtgggacatt ctgctgaacatcatcgaacggctccttcagcagctccagaccttggacagcccggagctc aggaccatcgtccatgacctgttgaccacggtggaggagctgtgtgaccagaacgagttc cacgggtctcaggagagatactttgaactggtggagagatgtgcggaccagaggcctgag tcctcccttctgaacctgatctcctatagagcgcagtccatccacccggccaaggacggc tggattcagaacctgcaggcgctgatggagagattcttcaggagcgagtcccgaggcgcc gtgcgcatcaaggtgctggacgtgctgtcctttgtgctgctcatcaacaggcagttctat gaggaggagctgattaactcagtggtcatctcgcagctctcccacatccccgaggataaa gaccaccaggtccgaaagctggccacccagttgctggtggacctggcagagggctgccac acacaccacttcaacagcctgctggacatcatcgagaaggtgatggcccgctccctctcc ccacccccggagctggaagaaagggatgtggccgcatactcggcctccttggaggatgtg aagacagccgtcctggggcttctggtcatccttcagaccaagctgtacaccctgcctgca agccacgccacgcgtgtgtatgagatgctggtcagccacattcagctccactacaagcac agctacaccctgccaatcgcgagcagcatccggctgcaggcctttgacttcctgttgctg ctgcgggccgactcactgcaccgcctgggcctgcccaacaaggatggagtcgtgcggttc agcccctactgcgtctgcgactacatggagccagagagaggctctgagaagaagaccagc ggccccctttctcctcccacagggcctcctggcccggcgcctgcaggccccgccgtgcgg ctggggtccgtgccctactccctgctcttccgcgtcctgctgcagtgcttgaagcaggag tctgactggaaggtgctgaagctggttctgggcaggctgcctgagtccctgcgctataaa gtgctcatctttacttccccttgcagtgtggaccagctgtgctctgctctctgctccatg ctttcaggcccaaagacactggagcggctccgaggcgccccagaaggcttctccagaact gacttgcacctggccgtggttccagtgctgacagcattaatctcttaccataactacctg gacaaaaccaaacagcgcgagatggtctactgcctggagcagggcctcatccaccgctgt gccagccagtgcgtcgtggccttgtccatctgcagcgtggagatgcctgacatcatcatc aaggcgctgcctgttctggtggtgaagctcacgcacatctcggccacagccagcatggcc gtcccactgctggagttcctgtccactctggccaggctgccgcacctctacaggaacttt gccgcggagcagtatgccagtgtgttcgccatctccctgccgtacaccaacccctccaag tttaatcagtacatcgtgtgtctggcccatcacgtcatagccatgtggttcatcaggtgc cgcctgcccttccggaaggatttcgtccctttcatcactaagggcctgcggtccaatgtc ctcttgtcttttgatgacacccccgagaaggacagcttcagggcccggagtactagtctc aacgagagacccaagagtctgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaggagagctctgcagccgaggccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatacagacgtccctcaccagtgccagcttg gggtctgcagatgagaactcggtggcccaggctgacgatagcctgaaaaacctccacctg gagctgacggaaacctgtctggacatgatggctcgatacgtcttctccaacttcacggct gtgccgaagaggtctcctgtgggcgagttcctcctagcgggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcactgtgacgacaagcgtgggaaccgggacccggtcgtta ctaggcctggactcgggggagctgcagtccggcccggagtcgagctccagccccggtgtg catgtgagacagaccaaggaggcgccggccaagctggagtcccaggctgggcagcaggtg tcccgtggggcccgggaccgcgtccgttccatgtcggggggccatggtcttcgagttggc gccctggacgtgccggcttcccagttcctgggcagtgccacttctccaggaccacggact gcaccagccgtgaaacctgagaaggcctcagctggcacccgggttcctatgcaggagaag acgaacctggcggcctatgtgcccctgctgacccagggctgggcggagatcctggtccgg aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccctttctcc tcggacatcaacaacatgcccctgcaggagctgtccaacgccctcatggcggctgagcgc ttcaaggagcaccgggacacagccctgtacaagtcactgtcggtgccggcagccagcacg gccaaaccccctcctctgcctcgctccaacacagtggcctctttctcctccctgtaccag tccagctgccaaggacagctgcacaggagcgtttcctgggcagactccgccgtggtcatg gaggagggaattccgggcgaggttcctgtgccggtggcgcccccagggttggaggacgtc gaggcagcgctaggcatggacaggcgcacagacgcctacagcaggtcgtcctcagtctcc agccaggaggagaagtcgctccacgcggaggagctggttggcaggggcatccccatcgag cgagccgtctcctcagagggtggccggccctctgtggacctctccttccagccctcgcag cccctgagcaagtccagctcctctcccgagctgcagactctgcaggacatccttggggac cctggggacaaggccgacgtgggccggctgagccctgaggttaaggcccggtcacagtca gggaccctggacggggaaagtgctgcctggtcggcctcgggcgaagacagtcggggccag cccgagggtcccttgccttccagctccccccgctcgcccagtggcctccggccccgaggt tacaccatctccgactcggccccatcacgcaggggcaagagagtagagagggatgcctta aagagcagagccacagcctccaatgcagagaaagtgccgggcatcaaccccagtttcgtg ttcctgcagctctaccattcccccttctttggcgacgagtcaaacaagccaatcctgctg cccaatgagtcacagtcctttgagcggtcggtgcagctcctcgaccagatcccatcatac gacacccacaagatcgccgtcctctatgttggagaaggccagagcaacagcgagctcgcc atcctgtccaacgagcatggctcctacaggtacacggagttcctgacgggcctgggccgg ctcatcgagctgaaggactgccagccggacaaggtgtacctgggaggcctggacgtgtgt ggtgaggacggccagttcacctactgctggcacgatgacatcatgcaagccgtcttccac atcgccaccctgatgcccaccaaggacgtggacaagcaccgctgcgacaagaagcgccac ctgggcaacgactttgtgtccattgtctacaatgactctggtgaggacttcaagctcggc accatcaagggccagttcaactttgtccacgtgatcgtcaccccgctggactacgagtgc aacctggtgtccctgcagtgcaggaaagacatggagggccttgtggacaccagcgtggcc aagatcgtgtctgaccgcaacctgcccttcgtggcccgccagatggccctgcacgcaaat atggcctcacaggtgcatcatagccgctccaaccccaccgacatctacccctccaagtgg attgcccggctccgccacatcaagaggctccgccagcggatctgcgaggaagccgcctac tccaaccccagcctgcctctggtgcaccctccgtcccataccaaagcccctgcacagact ccagccgagcccacacctggctatgaggtgggccagcggaagcgcctcatctcctcggtg gaggacttcaccgagtttgtgtga

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