KEGG   Pan troglodytes (chimpanzee): 469367
Entry
469367            CDS       T01005                                 
Symbol
PRKACB
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X6
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01522  Endocrine resistance
ptr04010  MAPK signaling pathway
ptr04014  Ras signaling pathway
ptr04020  Calcium signaling pathway
ptr04024  cAMP signaling pathway
ptr04062  Chemokine signaling pathway
ptr04081  Hormone signaling
ptr04082  Neuroactive ligand signaling
ptr04114  Oocyte meiosis
ptr04140  Autophagy - animal
ptr04211  Longevity regulating pathway
ptr04213  Longevity regulating pathway - multiple species
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04270  Vascular smooth muscle contraction
ptr04310  Wnt signaling pathway
ptr04340  Hedgehog signaling pathway
ptr04371  Apelin signaling pathway
ptr04530  Tight junction
ptr04540  Gap junction
ptr04611  Platelet activation
ptr04713  Circadian entrainment
ptr04714  Thermogenesis
ptr04720  Long-term potentiation
ptr04723  Retrograde endocannabinoid signaling
ptr04724  Glutamatergic synapse
ptr04725  Cholinergic synapse
ptr04726  Serotonergic synapse
ptr04727  GABAergic synapse
ptr04728  Dopaminergic synapse
ptr04740  Olfactory transduction
ptr04742  Taste transduction
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04910  Insulin signaling pathway
ptr04911  Insulin secretion
ptr04912  GnRH signaling pathway
ptr04913  Ovarian steroidogenesis
ptr04914  Progesterone-mediated oocyte maturation
ptr04915  Estrogen signaling pathway
ptr04916  Melanogenesis
ptr04918  Thyroid hormone synthesis
ptr04919  Thyroid hormone signaling pathway
ptr04921  Oxytocin signaling pathway
ptr04922  Glucagon signaling pathway
ptr04923  Regulation of lipolysis in adipocytes
ptr04924  Renin secretion
ptr04925  Aldosterone synthesis and secretion
ptr04926  Relaxin signaling pathway
ptr04927  Cortisol synthesis and secretion
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr04934  Cushing syndrome
ptr04935  Growth hormone synthesis, secretion and action
ptr04961  Endocrine and other factor-regulated calcium reabsorption
ptr04962  Vasopressin-regulated water reabsorption
ptr04970  Salivary secretion
ptr04971  Gastric acid secretion
ptr04976  Bile secretion
ptr05012  Parkinson disease
ptr05020  Prion disease
ptr05030  Cocaine addiction
ptr05031  Amphetamine addiction
ptr05032  Morphine addiction
ptr05034  Alcoholism
ptr05146  Amoebiasis
ptr05163  Human cytomegalovirus infection
ptr05165  Human papillomavirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05200  Pathways in cancer
ptr05203  Viral carcinogenesis
ptr05205  Proteoglycans in cancer
ptr05207  Chemical carcinogenesis - receptor activation
ptr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    469367 (PRKACB)
   04310 Wnt signaling pathway
    469367 (PRKACB)
   04024 cAMP signaling pathway
    469367 (PRKACB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    469367 (PRKACB)
   04081 Hormone signaling
    469367 (PRKACB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    469367 (PRKACB)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    469367 (PRKACB)
   04062 Chemokine signaling pathway
    469367 (PRKACB)
  09152 Endocrine system
   04911 Insulin secretion
    469367 (PRKACB)
   04922 Glucagon signaling pathway
    469367 (PRKACB)
   04923 Regulation of lipolysis in adipocytes
    469367 (PRKACB)
   04913 Ovarian steroidogenesis
    469367 (PRKACB)
   04915 Estrogen signaling pathway
    469367 (PRKACB)
   04921 Oxytocin signaling pathway
    469367 (PRKACB)
   04926 Relaxin signaling pathway
    469367 (PRKACB)
   04935 Growth hormone synthesis, secretion and action
    469367 (PRKACB)
   04918 Thyroid hormone synthesis
    469367 (PRKACB)
   04919 Thyroid hormone signaling pathway
    469367 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    469367 (PRKACB)
   04924 Renin secretion
    469367 (PRKACB)
   04925 Aldosterone synthesis and secretion
    469367 (PRKACB)
   04927 Cortisol synthesis and secretion
    469367 (PRKACB)
  09154 Digestive system
   04970 Salivary secretion
    469367 (PRKACB)
   04971 Gastric acid secretion
    469367 (PRKACB)
   04976 Bile secretion
    469367 (PRKACB)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    469367 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    469367 (PRKACB)
  09156 Nervous system
   04724 Glutamatergic synapse
    469367 (PRKACB)
   04727 GABAergic synapse
    469367 (PRKACB)
   04725 Cholinergic synapse
    469367 (PRKACB)
   04728 Dopaminergic synapse
    469367 (PRKACB)
   04726 Serotonergic synapse
    469367 (PRKACB)
   04720 Long-term potentiation
    469367 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    469367 (PRKACB)
  09157 Sensory system
   04740 Olfactory transduction
    469367 (PRKACB)
   04742 Taste transduction
    469367 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    469367 (PRKACB)
  09149 Aging
   04211 Longevity regulating pathway
    469367 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    469367 (PRKACB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    469367 (PRKACB)
   04714 Thermogenesis
    469367 (PRKACB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    469367 (PRKACB)
   05205 Proteoglycans in cancer
    469367 (PRKACB)
   05207 Chemical carcinogenesis - receptor activation
    469367 (PRKACB)
   05203 Viral carcinogenesis
    469367 (PRKACB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    469367 (PRKACB)
   05163 Human cytomegalovirus infection
    469367 (PRKACB)
   05165 Human papillomavirus infection
    469367 (PRKACB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    469367 (PRKACB)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    469367 (PRKACB)
   05020 Prion disease
    469367 (PRKACB)
  09165 Substance dependence
   05030 Cocaine addiction
    469367 (PRKACB)
   05031 Amphetamine addiction
    469367 (PRKACB)
   05032 Morphine addiction
    469367 (PRKACB)
   05034 Alcoholism
    469367 (PRKACB)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    469367 (PRKACB)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    469367 (PRKACB)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    469367 (PRKACB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptr01001]
    469367 (PRKACB)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:ptr03019]
    469367 (PRKACB)
   03036 Chromosome and associated proteins [BR:ptr03036]
    469367 (PRKACB)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     469367 (PRKACB)
Protein kinases [BR:ptr01001]
 Serine/threonine kinases: AGC group
  PKA family
   469367 (PRKACB)
Messenger RNA biogenesis [BR:ptr03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     469367 (PRKACB)
Chromosome and associated proteins [BR:ptr03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    469367 (PRKACB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C OST_P1
Other DBs
NCBI-GeneID: 469367
NCBI-ProteinID: XP_001135693
Ensembl: ENSPTRG00000000899
VGNC: 11804
UniProt: A0A2I3RRJ6 A0A6D2YBJ3
LinkDB
Position
1:complement(146838572..147000259)
AA seq 339 aa
MGLLKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAM
KILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSH
LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV
KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV
SGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVE
APFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
NT seq 1020 nt   +upstreamnt  +downstreamnt
atgggattgttgaaagagtttctagccaaagccaaagaagactttttgaaaaaatgggag
aatccaactcagaataatgccggacttgaagattttgaaaggaaaaaaacccttggaaca
ggttcatttggaagagtcatgttggtaaaacacaaagccactgaacagtattatgccatg
aagatcttagataagcagaaggttgttaaactgaagcaaatagagcatactttgaatgag
aaaagaatattacaggcagtgaattttcctttccttgttcgactggagtatgcttttaag
gataattctaatttatacatggttatggaatatgtccctgggggtgaaatgttttcacat
ctaagaagaattggaaggttcagtgagccccatgcacggttctatgcagctcagatagtg
ctaacattcgagtacctccattcactagacctcatctacagagatctaaaacctgaaaat
ctcttaattgaccatcaaggctatatccaggtcacagactttgggtttgccaaaagagtt
aaaggcagaacttggacattatgtggaactccagagtatttggctccagaaataattctc
agcaagggctacaataaggcagtggattggtgggcattaggagtgctaatctatgaaatg
gcagctggctatcccccattctttgcagaccaaccaattcagatttatgaaaagattgtt
tctggaaaggtccgattcccatcccacttcagttcagatctcaaggaccttctacggaac
ctgctgcaggtggatttgaccaagagatttggaaatctaaagaatggtgtcagtgatata
aaaacccacaagtggtttgccacgacagattggattgctatttaccagaggaaggttgaa
gctccattcataccaaagtttagaggctctggagataccagcaactttgatgactatgaa
gaagaagatatccgtgtctctataacagaaaaatgtgcaaaagaatttggtgaattttaa

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