| Entry |
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| Symbol |
PKLR
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| Name |
(RefSeq) pyruvate kinase PKLR isoform X1
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| KO |
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| Organism |
ptr Pan troglodytes (chimpanzee)
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| Pathway |
| ptr04932 | Non-alcoholic fatty liver disease |
| ptr04950 | Maturity onset diabetes of the young |
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| Module |
| ptr_M00001 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate |
| ptr_M00002 | Glycolysis, core module involving three-carbon compounds |
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| Brite |
KEGG Orthology (KO) [BR:ptr00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
469513 (PKLR)
00620 Pyruvate metabolism
469513 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
469513 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
469513 (PKLR)
04950 Maturity onset diabetes of the young
469513 (PKLR)
04932 Non-alcoholic fatty liver disease
469513 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:ptr04147]
469513 (PKLR)
Enzymes [BR:ptr01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
469513 (PKLR)
Exosome [BR:ptr04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
469513 (PKLR)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:93887318..93905711
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| AA seq |
585 aa
MVPQPQAHTESMSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQ
ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIK
AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQG
GPESDVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ
KIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVR
KANDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKV
FLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETA
KGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAA
AIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDV
DRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS |
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| NT seq |
1758 nt +upstreamnt +downstreamnt
atggtcccgcagccccaggcccacactgaaagcatgtcgatccaggagaacatatcatcc
ctgcagcttcggtcatgggtctctaagtcccaaagagacttagcaaagtccatcctgatt
ggggctccaggagggccagcggggtatctgcggcgggccagtgtggcccaactgacccag
gagctgggcactgccttcttccagcagcagcagctgccagctgctatggcagacaccttc
ctggaacacctctgcctactggacattgactctgagcccgtggctgctcgcagtaccagc
atcattgccaccatcgggccagcatctcgctccgtggagcgcctcaaggagatgatcaag
gccgggatgaacattgcgcgactcaacttctcccacggctcccacgagtaccatgctgag
tccatcgccaacgtccgggaggcggtggagagctttgcaggttccccactcagctaccgg
cccgtggccatcgccctggacaccaagggaccggagatccgcactgggatcctgcagggg
ggtccagagtcggacgtggagctggtgaagggctcccaggtgctggtgactgtggacccc
gcgttccggacgcgggggaacgcgaacaccgtgtgggtggactaccccaatattgtccgg
gtcgtgccggtggggggccgcatctacattgacgacgggctcatctccctagtggtccag
aaaatcggcccagagggactggtgacccaagtggagaacggcggcgtcctgggcagccgg
aaaggcgtgaacttgccaggggcccaggtggacttgcccgggctgtccgagcaggacgtc
cgagacctgcgcttcggggtggagcatggggtggacatcgtctttgcctcctttgtgcgg
aaagccaacgacgtggctgccgtcagggctgctctgggtccggaaggacacggcatcaag
atcatcagcaaaattgagaaccacgaaggcgtgaagaggtttgatgaaatcctggaggtg
agcgacggcatcatggtggcacggggggacctaggcatcgagatcccagcagagaaggtt
ttcctggctcagaagatgatgattgggcgctgcaacttggcgggcaagcctgttgtctgt
gccacacagatgctggagagcatgattaccaagccccggccaacgagggcagagacaagc
gatgtcgccaatgctgtgctggatggggctgactgcatcatgctgtcaggggagactgcc
aagggcaacttccctgtggaagcggtgaagatgcagcatgcgattgcccgggaggcagag
gccgcagtgtaccaccggcagctgtttgaggagctacgtcgggcagcgccactaagccgt
gatcccactgaggtcaccgccattggtgctgtggaggctgccttcaagtgctgtgctgct
gccatcattgtgctgaccacaactggccgctcagcccagcttctgtctcggtaccgacct
cgggcagcagtcattgctgtcacccgctctgcccaggctgcccgccaggtccacttatgc
cgaggagtcttccccttgctttaccgtgaacctccagaagccatctgggcagatgatgta
gatcgccgggtgcaatttggcattgaaagtggaaagctccgtggcttcctccgtgttgga
gacctggtgattgtggtgacaggctggcgacctggctccggctacaccaacatcatgcgg
gtgctaagcatatcctga |
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