KEGG   Pan troglodytes (chimpanzee): 470996
Entry
470996            CDS       T01005                                 
Symbol
PLD1
Name
(RefSeq) phospholipase D1 isoform X1
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00564  Glycerophospholipid metabolism
ptr00565  Ether lipid metabolism
ptr01100  Metabolic pathways
ptr04014  Ras signaling pathway
ptr04024  cAMP signaling pathway
ptr04071  Sphingolipid signaling pathway
ptr04072  Phospholipase D signaling pathway
ptr04144  Endocytosis
ptr04666  Fc gamma R-mediated phagocytosis
ptr04724  Glutamatergic synapse
ptr04912  GnRH signaling pathway
ptr04928  Parathyroid hormone synthesis, secretion and action
ptr05200  Pathways in cancer
ptr05208  Chemical carcinogenesis - reactive oxygen species
ptr05212  Pancreatic cancer
ptr05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    470996 (PLD1)
   00565 Ether lipid metabolism
    470996 (PLD1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    470996 (PLD1)
   04072 Phospholipase D signaling pathway
    470996 (PLD1)
   04071 Sphingolipid signaling pathway
    470996 (PLD1)
   04024 cAMP signaling pathway
    470996 (PLD1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    470996 (PLD1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    470996 (PLD1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    470996 (PLD1)
   04928 Parathyroid hormone synthesis, secretion and action
    470996 (PLD1)
  09156 Nervous system
   04724 Glutamatergic synapse
    470996 (PLD1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    470996 (PLD1)
   05208 Chemical carcinogenesis - reactive oxygen species
    470996 (PLD1)
   05231 Choline metabolism in cancer
    470996 (PLD1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    470996 (PLD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ptr04131]
    470996 (PLD1)
Enzymes [BR:ptr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     470996 (PLD1)
Membrane trafficking [BR:ptr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    470996 (PLD1)
 Endosome - Golgi transport
  Others
   Others
    470996 (PLD1)
SSDB
Motif
Pfam: PLDc PX PLDc_2 PH DUF3785
Other DBs
NCBI-GeneID: 470996
NCBI-ProteinID: XP_003310147
Ensembl: ENSPTRG00000015626
VGNC: 7084
UniProt: H2R1L6 A0A6D2W645
LinkDB
Position
2:complement(174746561..174956490)
AA seq 1074 aa
MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF
KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR
KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC
CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID
NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG
YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY
KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI
DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPDQNLPIQKS
IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHNADSISSIDSTSSYFNHYRSHHNLIHGL
KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL
DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL
PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE
NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVLPLLPGFEGDISTGGGNALQ
AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL
IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF
RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI
NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
NT seq 3225 nt   +upstreamnt  +downstreamnt
atgtcattgaaaaacgagccacgggtaaatacctctgcactgcagaaaattgctgctgac
atgagtaatatcatagaaaatctggacacgcgggaactccactttgagggagaggaggta
gactacgacgtgtctcccagcgatcccaagatacaagaagtgtatatccctttctctgct
atttataacactcaaggatttaaggagcctaatatacagacgtatctctccggctgtcca
ataaaagcacaagttctggaagtggaacgcttcacatctacaacaagggtaccaagtatt
aatctttacactattgaattaacacatggggaatttaaatggcaagttaagaggaaattc
aagcattttcaagaatttcacagagagctgctcaagtacaaagcctttatccgaatcccc
attcccactagaagacacacgtttaggaggcaaaacgtcagagaggagcctcgagagatg
cccagtttgccccgttcatctgaaaacatgataagagaagaacaattccttggtagaaga
aaacaactggaagattacttgacaaagatactaaaaatgcccatgtatagaaactatcat
gccacaacagagtttcttgatataagccagctgtctttcatccatgatttgggaccaaag
ggcatagaaggtatgataatgaaaagatctggaggacacagaataccgggcttgaattgc
tgtggtcagggaagagcctgctacagatggtcaaaaagatggttaatagtgaaagattcc
tttttattgtatatgaaaccagacagcggtgccattgccttcgtcctgctggtagacaaa
gaattcaaaattaaggtggggaagaaggagacagaaacgaaatatggaatccgaattgat
aatctttcaaggacacttattttaaaatgcaacagctatcgacatgctcggtggtgggga
ggggctatagaagaattcatccagaaacatggcaccaactttctcaaagatcatcgattt
gggtcatatgctgctatccaagagaatgctttagctaaatggtatgttaatgccaaagga
tattttgaagatgtggcaaatgcaatggaagaggcaaatgaagagatttttatcacagac
tggtggctgagtccagaaatcttcctgaaacgcccagtggttgagggaaatcgttggagg
ttggactgcattcttaaacgaaaagcacaacaaggagtgaggatcttcataatgctctac
aaagaggtggaactcgctcttggcatcaatagtgaatacaccaagaggactttgatgcgt
ctacatcccaacataaaggtgatgagacacccggatcatgtgtcatccaccgtctatttg
tgggctcaccatgagaagcttgtcatcattgaccaatcggtggcctttgtgggagggatt
gacctggcctatggaaggtgggacgacaatgagcacagactcacagacgtgggcagtgtg
aagcgggtcacttcaggaccatctctgggttccctcccacctgctgcaatggagtctatg
gaatccttaagactcaaagataaaaatgagcctgatcaaaacctacccatccagaagagt
attgatgatgtggattcaaaactgaaaggaataggaaagccaagaaagttctccaaattt
agtctctacaagcagctccacaggcaccacctgcacaacgcagatagcatcagcagcatt
gacagcacctccagttattttaatcactatagaagtcatcacaatttaatccatggttta
aaaccccacttcaaactctttcacccatccagtgagtctgagcaaggactcactagacct
catgctgataccgggtccatccgcagtttacagacaggtgtgggagagctgcatggggaa
accagattctggcatggaaaggactactgcaatttcgtcttcaaagactgggttcaactt
gataaaccttttgctgatttcattgacaggtactccacgccccggatgccctggcatgac
attgcctctgcagtccacgggaaggcggctcgtgatgtggcacgtcacttcatccagcgc
tggaacttcacgaaaattatgaaatcaaaatatcggtccctttcttatccttttctgctt
ccaaagtctcaaacaacagcccatgagttgagatatcaagtgcctgggtctgtccatgct
aacgtacagttgctccgctctgctgctgattggtctgctggtataaagtaccatgaagag
tccatccacgccgcttatgtccatgtgatagagaacagcaggcactatatctatatcgaa
aaccagtttttcataagctgtgctgatgacaaagttgtgttcaacaagataggtgatgcc
attgcccagaggatcctgaaagctcacagggaaaaccagaaataccgggtatatgtcgtg
ttaccacttctgccagggttcgaaggagacatttcaaccggtggaggaaatgctctacag
gcaatcatgcacttcaactacagaaccatgtgcagaggagaaaattccatccttggacag
ttaaaagcagagcttggtaatcagtggataaattacatatcattctgtggtcttagaaca
cacgcagagctcgaaggaaacctagtcactgagcttatctatgtccacagcaagttgtta
attgctgatgataacactgttattattggctctgccaacataaatgaccgcagcatgctg
ggaaagcgtgacagtgaaatggctgtcattgtgcaagatacagagactgttccttcagta
atggatggaaaagagtaccaagctggccggtttgcccgaggacttcggctacagtgcttt
agggttgtccttggctatcttgatgacccaagtgaggacattcaggatccagtgagtgac
aaattcttcaaggaggtgtgggtttcgacagcagctcgaaatgctacaatttatgacaag
gttttccggtgccttcccaatgatgaagtacacaatttaattcagctgagagactttata
aacaagcccgtattagctaaggaagatcccattcgagctgaggaggaactgaagaagatc
cgtggatttttggtgcaattccccttttatttcttgtctgaagaaagcctactgccttct
gttggaaccaaagaggccatagtgcccatggaggtttggacttaa

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