Pan troglodytes (chimpanzee): 472732
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Entry
472732 CDS
T01005
Symbol
WRN
Name
(RefSeq) bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN isoform X1
KO
K10900
werner syndrome ATP-dependent helicase [EC:
5.6.2.4
]
Organism
ptr
Pan troglodytes (chimpanzee)
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ptr03032
]
472732 (WRN)
03400 DNA repair and recombination proteins [BR:
ptr03400
]
472732 (WRN)
Enzymes [BR:
ptr01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.4 DNA 3'-5' helicase
472732 (WRN)
DNA replication proteins [BR:
ptr03032
]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
472732 (WRN)
DNA repair and recombination proteins [BR:
ptr03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
RecQ family DNA helicases
472732 (WRN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_pol_A_exo1
DEAD
Helicase_C
HTH_40
RQC
HRDC
RecQ_Zn_bind
ResIII
Laminin_II
SAM_GIDA_C
Motif
Other DBs
NCBI-GeneID:
472732
NCBI-ProteinID:
XP_063673071
Ensembl:
ENSPTRG00000020145
VGNC:
7604
LinkDB
All DBs
Position
7:39426720..39564643
Genome browser
AA seq
1405 aa
AA seq
DB search
MSEKKLETTAQQRKCPEWMNVQNKRCAVEERKACVWKSVFEDDLPFLEFTGSIVYSYDAS
DCSLLSEDISMSLSDGDVVGFDMEWPPLYNRGKLGKVALIQLCVSESKCYLFHISSMSVF
PQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELTDVANKKLKCTETWSLNSL
VKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNLEILDDTVQRFAIN
KEEEILLSDMNKQLTSISEEVMDLAKHLPHAFSKLENPRRVSILLKDISENLYSLRRMII
GSTNIETELRPSNNLNLLSFGDSTTGGVQQKQIREHEVLIHVADETWDPTLDHLAKHDGE
GVLGNKVERKEDGFEDGVEDNKLKENMERACLMSLDITEHELQILEQQAQEEYLSDTAYK
STEHLSPNNDENDTSYVIESDEDLEMEMLKSLENLNSGTVEPTHSKCLKMERNLGLLTKE
EEEDDENEANEGEEDDDKDFLLPAPSEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDN
VAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENV
LTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRNSFRKL
GSLKTALPMVPIIALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNIL
QDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFNTRKDIH
HRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVL
WAPADINLNRHLLTEIRNEKFRLYKLKMTAKMEKYLHSSRCRRQIILSHFEDKQVQKASL
GIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGEKFGIGLPILFLR
GSNSQRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEGFLEEVSRYNKFMKICILTKEG
RNWLHKANTESQSLILQANEELCPKKFLLPSSKTVSSGTKEHCYNQVPVELTTEKKSNLE
KLYSYKPCDKISSGSNISKKSIMVQSPEKAYSSSEPIISAQEQETQIVLYGKLVEARQKH
ANKMDVPPAILATNKILVDMAKMRPTTVENVKRIDGVSEGKAAMLAPLLEVIKHFCQTNS
VQTDLFSSTKPQEEQKTSLVAKNKICTLSQSMAITYSLFQEKKMPLKSIAESRILPLMTI
GMHLSQAVKAGCPLDLERAGLTPEVQKIIADVIRNPPVNSDMSKISLIRMLVPENIDTYL
IHMAIEILKHGPDSGLQPSCDVNKRRCFPSSEEICSSSKRSKEEVGINTETSSAERKRRL
PVWFAKGSDTSKKLMDKTKRGGLFS
NT seq
4218 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaaaaaaaattggaaacaactgcacagcagcggaaatgtcctgaatggatgaat
gtgcagaataaaagatgtgctgtagaagaaagaaaggcatgtgtttggaagagtgttttt
gaagatgacctccccttcttagaattcactggatccattgtgtatagttacgatgctagt
gattgctctttgctgtcagaagatattagcatgagtctatcagatggggatgtggtggga
tttgacatggagtggccaccattatacaatagagggaaacttggcaaagttgcactaatt
cagttgtgtgtttctgagagcaaatgttacttgttccacatttcttccatgtcagttttt
ccccagggattaaaaatgttgcttgaaaataaagcagttaaaaaggcaggtgtaggaatt
gaaggagatcagtggaaacttctacgtgactttgatatcaaattgaagaattttgtggag
ttgacagatgttgccaataaaaagctgaaatgtacagagacctggagcctcaacagtctg
gttaaacacctcttaggtaaacagctcctgaaagacaagtctatccgctgtagcaattgg
agtaaatttcctctcactgaggaccagaaactgtatgcagccactgatgcttatgctggt
tttattatttaccgaaatttagagattttggatgatactgtgcaaaggtttgctataaat
aaagaggaagaaatcctacttagcgacatgaacaaacagttgacttcaatctctgaggaa
gtgatggatctggctaagcatcttcctcatgctttcagtaaactggaaaacccacggagg
gtttctatcttactaaaggatatttcagaaaatctatattcactgaggaggatgataatt
gggtctactaacattgagactgaactgaggcccagcaataatttaaacttattatccttt
ggagattcaactactgggggagtacaacagaaacaaattagagaacatgaagttttaatt
cacgttgcagatgaaacatgggacccaacacttgatcatttagctaaacatgatggagaa
ggtgtacttggaaataaagtggaacgaaaagaagatggatttgaagatggagtagaagac
aacaaattgaaagagaatatggaaagagcttgtttgatgtcgttagatattacagaacat
gaactccaaattttggaacagcaggctcaggaagaatatcttagtgatactgcttataaa
tctactgagcatttatctcccaataatgatgaaaacgatacgtcctatgtaattgagagt
gatgaagatttagaaatggagatgcttaagtctttagaaaacctcaacagtggcacggta
gaaccaactcattctaaatgcttaaaaatggaaagaaatctgggtcttcttactaaagaa
gaagaagaagatgatgaaaatgaagctaatgaaggggaagaagatgatgataaggacttt
ttgttgccagcacccagtgaagagcaagttacttgcctcaagatgtactttggccattcc
agttttaaaccagttcagtggaaagtgattcattcagtattagaagaaagaagagataat
gttgctgtcatggcaactggatatggaaagagtttgtgcttccagtatccacctgtttat
gtaggcaagattggccttgttatctctccccttatttctctgatggaagaccaagtgcta
cagcttaaaatgtccaacatcccagcttgcttccttggatcagcacagtcagaaaatgtt
ctaacagatattaaattaggtaaataccggattgtatacgtaactccagaatactgttca
ggtaacatgggcctgctccagcaacttgaggctgatattggtatcacgctcattgctgtg
gatgaggctcactgtatttctgagtgggggcatgattttaggaattcattcaggaagttg
ggctccctgaagacagcactgccaatggttccaatcattgcacttactgctactgcaagt
tcctcaatccgggaagacattgtacgttgcttaaatctgagaaatcctcagatcacctgt
actggttttgatcgaccaaacctgtatttagaagttaggcgaaaaacagggaatatcctt
caggatctgcagccatttcttgtcaaaacaagttcccactgggaatttgaaggtccaaca
atcatctactgtccttctagaaaaatgacacaacaagttacaggtgaacttaggaaactg
aatctatcctgtggaacataccatgcgggcatgagttttaacacaaggaaagacattcat
cataggtttgtaagagatgaaattcagtgtgtcatagctaccatagcttttggaatgggc
attaataaagctgacattcgccaagtcattcattacggtgctcctaaggacatggaatca
tattatcaggagattggtagagctggtcgtgatggacttcaaagttcttgtcacgtcctc
tgggctcctgcagacattaacttaaataggcaccttcttactgagatacgtaatgagaag
tttcgattatacaaattaaagatgacggcaaagatggaaaaatatcttcattctagcaga
tgtaggagacaaatcatcttgtctcattttgaggacaaacaagtacaaaaagcctccttg
ggaattatgggaactgaaaaatgctgtgataattgcaggtccagattggatcattgctat
tccatggatgactcagaggatacatcctgggactttggtccacaagcatttaagcttttg
tctgctgtggacatcttaggcgaaaaatttggaattgggcttccaattttatttctccga
ggatctaattctcagcgtcttgccgatcaatatcgcaggcacagtttatttggcactggc
aaggatcaaacagagagttggtggaaggctttttcccgtcagctgatcactgagggattc
ttggaagaagtttctcggtataacaaatttatgaagatttgcatccttacgaaagagggt
agaaattggcttcataaagctaatacagaatctcagagcctcatccttcaagctaatgaa
gaattgtgtccaaagaagtttcttctgcctagttcaaaaactgtatcttcgggcaccaaa
gagcattgttataatcaagtaccagttgaattaactacagagaagaagtctaacttggag
aagttatattcttataaaccatgtgataagatttcttctgggagtaacatttctaaaaaa
agtatcatggtacagtcaccagaaaaagcttacagttcctcagagcctattatttcggca
caagagcaggagactcagattgtgttatatggcaaattggtagaagctaggcagaaacat
gccaataaaatggatgttcccccagctattctggcaaccaacaagatactggtggatatg
gccaaaatgagaccaactacggttgaaaacgtaaaaaggattgatggtgtttctgaaggc
aaagctgccatgttggcccctctgttggaagtcatcaaacatttctgccaaacaaatagt
gttcagacagacctcttttcaagtacaaaacctcaagaagaacagaagacgagtctggta
gcaaaaaataaaatatgcacactttcacagtctatggccatcacatactctttattccaa
gaaaagaagatgcctttgaagagcatagctgagagcaggattctgcctcttatgacaatt
ggcatgcacttatcccaagcggtgaaagctggctgcccccttgatttggagcgagcaggc
ctgactccagaggttcagaagattattgctgatgttatccgaaaccctcccgtcaactca
gatatgagtaaaattagcctaatcagaatgttagttcctgaaaacattgacacgtacctt
atccacatggcaattgagatccttaaacatggtcctgacagcggacttcaaccttcatgt
gatgtcaacaaaaggagatgttttcccagttctgaagagatctgttcaagttctaagaga
agcaaggaagaagtaggcatcaatactgagacttcatctgcagagagaaagagacgatta
cctgtgtggtttgccaaaggaagtgataccagcaagaaattaatggacaaaacgaaaagg
ggaggtctttttagttaa
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