Pan troglodytes (chimpanzee): 473114
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Entry
473114 CDS
T01005
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04015
Rap1 signaling pathway
ptr04024
cAMP signaling pathway
ptr04062
Chemokine signaling pathway
ptr04510
Focal adhesion
ptr04650
Natural killer cell mediated cytotoxicity
ptr04660
T cell receptor signaling pathway
ptr04662
B cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04666
Fc gamma R-mediated phagocytosis
ptr04670
Leukocyte transendothelial migration
ptr04810
Regulation of actin cytoskeleton
ptr05135
Yersinia infection
ptr05205
Proteoglycans in cancer
ptr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
473114 (VAV2)
04024 cAMP signaling pathway
473114 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
473114 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
473114 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
473114 (VAV2)
04660 T cell receptor signaling pathway
473114 (VAV2)
04662 B cell receptor signaling pathway
473114 (VAV2)
04664 Fc epsilon RI signaling pathway
473114 (VAV2)
04666 Fc gamma R-mediated phagocytosis
473114 (VAV2)
04670 Leukocyte transendothelial migration
473114 (VAV2)
04062 Chemokine signaling pathway
473114 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
473114 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
473114 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
473114 (VAV2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
CAMSAP_CH
SH3_2
CH
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
C1_1
PH
DUF7145
RHG20_PH
C1_2
PLU-1
CDC24
SH2_2
PH_10
zf-RING-like
zf-RING_16
Motif
Other DBs
NCBI-GeneID:
473114
NCBI-ProteinID:
XP_016817514
Ensembl:
ENSPTRG00000021525
VGNC:
4899
LinkDB
All DBs
Position
11:4410020..4645418
Genome browser
AA seq
891 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSI
AQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDGGDDIYEDIIKVEV
QQPMKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLE
DLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASRE
DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEA
MQDLAMYINEVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR
YLFLFDKVVIVCKRKGYSYELKEIIELLFHKMTDDPMNNKDVKKQAGFPLPSHPAVLGGG
LWSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQ
MYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGP
GPKMVAVQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSV
KPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERF
AISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPY
KSRERSASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNF
AARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtggtgtggccctcggccgtggtcttcgacctggcgcaggcgctgcgcgacggg
gtccttctgtgccagctgctgcacaacctctcccccggctccatcgacctcaaggacatc
aacttccggccgcagatgtcccagtttctgtgtttgaagaacatacgcaccttcctgaaa
gtctgccacgataaattcggattaaggaacagcgagctgtttgacccctttgacctcttc
gatgtgcgagacttcggaaaggtcatctccgcggtgtcgaggctctccctgcacagcatc
gcgcagaacaaaggcatcaggccttttccctcagaggagaccacagagaatgacgatgac
gtctaccgcagcctggaggagctggccgatgagcatgacctgggggaggacatctacgac
tgcgtcccgtgtgaagatggaggggatgacatctatgaggacatcatcaaggtggaggtg
cagcagcccatgaaaatgggcatgactgaggatgacaagaggaactgctgcctgctggag
atccaggagaccgaggccaagtactaccgcaccctggaggacattgagaagaactacatg
agccccctgcggctggtgctgagcccggcggacatggcagctgtcttcattaacctggag
gacctgatcaaggtgcatcacagcttcctgagggccatcgacgtgtccgtgatggttggg
ggcagcacgctggccaaggtcttcctcgatttcaaggaaaggctcctgatctacggggag
tactgcagccacatggagcacgcccagaacacactgaaccagctcctggccagccgggag
gacttcaggcagaaagtcgaggagtgcacgctgaaggtccaggatggaaaatttaagctg
caagacctgctggtggtccccatgcagagggtgctcaaataccacctgctcttgaaggag
cttctgagccattctgcggaacggcctgagaggcagcagctcaaagaagcactggaagcc
atgcaggacttggcgatgtacatcaatgaagttaaacgggacaaggagaccttgaggaaa
atcagcgaatttcagagttctatagaaaatttgcaagtgaaactggaggaatttggaaga
ccaaagattgacggggaactgaaagtccggtccatagtcaaccacaccaagcaggacagg
tacttgttcctgtttgacaaggtggtcatcgtctgcaagcggaagggctacagctacgag
ctcaaggagatcatcgagctgctgttccacaagatgaccgacgaccccatgaacaacaag
gacgtcaagaagcaagcaggctttcctctcccgtcccaccctgcggtgcttggaggaggg
ctgtggtctcacgggaaaatgtggtcctacggcttctacctaattcaccttcaaggaaag
cagggcttccagtttttctgcaaaacagaagatatgaagaggaagtggatggagcagttt
gagatggccatgtcaaacatcaagccagacaaagccaatgccaaccaccacagtttccag
atgtacacgtttgacaagaccaccaactgcaaagcctgcaaaatgttcctcaggggcacc
ttctaccagggatacatgtgtaccaagtgtggcgtcggggcacacaaggagtgcctggaa
gtgatacctccctgcaagttcacttctcctgcagatctggacgcctccggagcgggacca
ggtcccaagatggtggccgtgcagaattaccatggcaacccagcccctcccgggaagcct
gtgctgaccttccagacgggcgacgtgcttgagctgctgaggggcgaccctgagtctccg
tggtgggagggtcgtctggtgcaaaccaggaagtcagggtatttccccagctcatctgtg
aagccctgccctgtggatggaaggccgcccatcagccggccgccatcccgggagattgac
tacactgcatacccctggtttgcaggtaacatggagaggcagcagacggacaacctgctc
aagtcccacgccagtgggacctacctgatcagggagcggcctgccgaggctgagcgcttt
gcaataagcatcaagttcaatgacgaggtgaagcacatcaaggtggtggagaaggacaac
tggatccacatcacagaggccaagaaattcgacagcctcctggagttggtggagtactac
cagtgccactcactgaaggagagcttcaagcagctggacaccacactcaagtacccctac
aagtcccgggaacgttcggcctccagggcctccagccggtccccagcttcctgtgcttcc
tacaacttttcttttctcagtcctcagggcctcagctttgcttctcagggcccctccgct
cccttctggtcagtgttcacgccccgcgtcatcggcacggctgtggccagatacaacttt
gccgcccgagacatgagggagctttcgctgcgggagggtgacgtggtgaggatctacagc
cgcatcggcggagaccagggctggtggaagggcgagaccaatggacggattggctggttt
ccttcaacgtacgtagaagaggagggtatccagtga
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