KEGG   Pan troglodytes (chimpanzee): 737449
Entry
737449            CDS       T01005                                 
Symbol
CTSL
Name
(RefSeq) procathepsin L
  KO
K01365  cathepsin L [EC:3.4.22.15]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04140  Autophagy - animal
ptr04142  Lysosome
ptr04145  Phagosome
ptr04210  Apoptosis
ptr04612  Antigen processing and presentation
ptr05205  Proteoglycans in cancer
ptr05323  Rheumatoid arthritis
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    737449 (CTSL)
   04142 Lysosome
    737449 (CTSL)
   04140 Autophagy - animal
    737449 (CTSL)
  09143 Cell growth and death
   04210 Apoptosis
    737449 (CTSL)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    737449 (CTSL)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    737449 (CTSL)
  09163 Immune disease
   05323 Rheumatoid arthritis
    737449 (CTSL)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    737449 (CTSL)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ptr01002]
    737449 (CTSL)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ptr03110]
    737449 (CTSL)
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ptr00537]
    737449 (CTSL)
Enzymes [BR:ptr01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.15  cathepsin L
     737449 (CTSL)
Peptidases and inhibitors [BR:ptr01002]
 Cysteine peptidases
  Family C1: papain family
   737449 (CTSL)
Chaperones and folding catalysts [BR:ptr03110]
 Intramolecular chaperones
  Papain family
   737449 (CTSL)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ptr00537]
 Others
  737449 (CTSL)
SSDB
Motif
Pfam: Peptidase_C1 Inhibitor_I29 Peptidase_C1_2 Styelin
Other DBs
NCBI-GeneID: 737449
NCBI-ProteinID: XP_003312197
Ensembl: ENSPTRG00000021080
VGNC: 4666
UniProt: H2QXF0 A0A6D2WE91
LinkDB
Position
11:complement(50693040..50698840)
AA seq 333 aa
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
NT seq 1002 nt   +upstreamnt  +downstreamnt
atgaatcctacactcatccttgctgccttttgcctgggaattgcctcagctactctaaca
tttgatcacagtttagaggcacagtggaccaagtggaaggcgatgcacaacagattatac
ggcatgaatgaagaaggatggaggagagcagtgtgggagaagaacatgaagatgattgaa
ctgcacaatcaggaatacagggaagggaaacacagcttcacaatggccatgaacgccttt
ggagacatgaccagtgaagaattcaggcaggtgatgaatggctttcaaaaccgtaagccc
aggaaggggaaagtgttccaggaacctctgttttatgaggcccccagatctgtggattgg
agagagaaaggctacgtgactcctgtgaagaatcagggtcagtgtggttcttgttgggct
tttagcgctactggtgctcttgaaggacagatgttccggaaaactgggaggcttatctca
ctgagtgagcagaatctggtagactgctctgggcctcaaggcaatgagggctgcaatggt
ggcctaatggattatgctttccagtatgttcaggataatggaggcctggactctgaggaa
tcctatccatatgaggcaacagaagaatcctgtaagtacaatcccaagtattctgttgct
aatgacaccggctttgtggacatccctaagcaggagaaggccctgatgaaggcagttgca
actgtggggcccatttctgttgctattgatgcaggtcatgagtccttcctgttctataaa
gaaggcatttattttgagccagactgtagcagtgaagacatggatcatggtgtgctggtg
gttggctacggatttgaaagcacagaatcggataacaataaatattggctggtgaagaac
agctggggtgaagaatggggcatgggtggctacgtaaagatggccaaagaccggagaaac
cattgtggaattgcctcagcagccagctaccccactgtgtga

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